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Differential expression of microRNAs in the brains of mice subjected to increasing grade of mild traumatic brain injury.

R Chandran | A Sharma | M Bhomia | NS Balakathiresan | BE Knollmann-Ritschel | RK Maheshwari
Brain injury | 2017

To investigate the effect of heterogeneity in mTBI on miRNA expression in mouse brain and to identify molecular pathways targeted by the modulated miRNAs.

Pubmed ID: 27819514

TBI Model

  • Weight-drop model

    • Animal Information

  • Species: mouse
  • Strain: C57BL/6
  • Age (weeks): 10 - 12
  • Weight (grams): 28 - 28

    • Assessments

    Bioanalyzer DIANA mirPath, Histology, RT-PCR, qRT-PCR, Hematoxylin and Eosin

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    custom-built weight-drop device

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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