Searching across hundreds of databases

Our searching services are busy right now. Please try again later

  • Register
X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

X

Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.

No
Yes

Does Decorin Protect Neuronal Tissue via Its Antioxidant and Antiinflammatory Activity from Traumatic Brain Injury? An Experimental Study.

R Özay | E Türkoğlu | B Gürer | H Dolgun | O Evirgen | Bİ Ergüder | N Hayırlı | L Gürses | Z Şekerci | ER Yılmaz
World neurosurgery | 2017 Jan

The development of secondary brain injury via oxidative stress after traumatic brain injury (TBI) is well known. Decorin (DC) inactivates transforming growth factor β1, complement system, and tumor necrosis factor α, which are related to oxidative stress and apoptosis. Consequently, the aim of the present study was to evaluate the role of DC on TBI.

Pubmed ID: 27744073

TBI Model

  • Weight-drop model
  • Marmarou's Weight-drop model

    • Animal Information

  • Species: rat
  • Strain: Wistar Albino
  • Age (weeks): No age reported
  • Weight (grams): 250 - 300

    • Assessments

    Histology, Lowry method, Tissue Caspase-3, Tissue Glutathione Peroxidase, Tissue Malondialdehyde, Tissue Superoxide Dismutase

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

    Recent News Entries

    Contact Us

    Department of Neurosciences, School of Medicine

    University of California, San Diego





    About SciCrunch | Privacy Policy | Terms of Service

    SciCrunch