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The Effectiveness of Trigeminal Nerve Stimulation on Traumatic Brain Injury.

Q Yang | S Zhang | Z Xu | L Liu | S Fan | S Wu | C Ma
Neuromodulation : journal of the International Neuromodulation Society | 2022 Dec

Trigeminal nerve stimulation (TNS) is a promising strategy in treating diseases of the nervous system. In this study, the effects of TNS on traumatic brain injury (TBI) were investigated in a mouse model.

Pubmed ID: 35088758

TBI Model

  • Weight-drop model

    • Animal Information

  • Species: mouse
  • Strain: C57BL/6
  • Age (weeks): No age reported
  • Weight (grams): 25 - 35

    • Assessments

    Enzyme-linked immunosorbent assay (ELISA), Evans blue dye extravasation, Functional Magnetic resonance imaging (MRI), Immunofluorescence, Western blot, Brain water content, Neurological Severity Score (NSS), wire grip test, motion test

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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