RETRACTED: Dexmedetomidine exerts neuroprotective effect via the activation of the PI3K/Akt/mTOR signaling pathway in rats with traumatic brain injury.

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the reliability of the Western blot results in Figures 3A, 5C and 7A which appear to have a similar phenotype as many other publications, as detailed here: https://pubpeer.com/publications/7D9475A7397928053FFE9442F8E943; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Several additional suspected image duplication issues were also identified in Figures 3A, 5A, and 7A. The journal requested the corresponding authors comment on these concerns and provide the raw data. The authors were unable to provide a satisfactory explanation or the raw data. The Supervision Committee of the National Natural Science Foundation of China launched an investigation into several papers of Jiangsu Normal University, including this one, and found evidence of "Falsification of pictures or data, fabrication of research process, use of others' signatures without consent, and false information in project final reports", as detailed here: https://www.nsfc.gov.cn/publish/portal0/tab442/info85495.htm. The Academic Committee at Jiangsu Normal University requested retraction of the article. The Editor-in-Chief assessed the case and decided to retract the article.

Pubmed ID: 28903184