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Inhibition of TRPA1 Attenuates Oxidative Stress-induced Damage After Traumatic Brain Injury via the ERK/AKT Signaling Pathway.

XJ Yang | S Ling | ML Zhou | HJ Deng | M Qi | XL Liu | C Zhen | YX Chen | XR Fan | ZY Wu | FC Ma | J Rong | GF Di | XC Jiang
Neuroscience | 2022 Jul 01

Pubmed ID: 35158017

TBI Model

  • Weight-drop model

    • Animal Information

  • Species: mouse
  • Strain: C57BL/6J
  • Age (weeks): No age reported
  • Weight (grams): 28 - 32

    • Assessments

    Dichlorofluorescein Diacetate Dye, Immunofluorescence, Neurological Severity Score )NSS), Nissl staining, TUNEL staining, Western Blot, Optical density, qRT-PCR

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Contact Us

    Department of Neurosciences, School of Medicine

    University of California, San Diego





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