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Efficacy of Deep Brain Stimulation on the Improvement of the Bladder Functions in Traumatic Brain Injured Rats.

C Praveen Rajneesh | JC Liou | TH Hsieh | HY Chin | CW Peng
Brain sciences | 2020 Nov 12

Traumatic brain injuries (TBIs) are a prime public health challenge with a high incidence of mortality, and also reflect severe economic impacts. One of their severe symptoms is bladder dysfunction. Conventional therapeutic methods are not effective in managing bladder dysfunction. Henceforth, a research endeavor was attempted to explore a new therapeutic approach for bladder dysfunction through deep brain stimulation (DBS) procedures in a TBI animal model.

Pubmed ID: 33198259

TBI Model

  • Weight-drop model
  • Marmarou’s impact acceleration model
  • Animal Information

  • Species: rat
  • Strain: Sprague-Dawley
  • Age (weeks): No age reported
  • Weight (grams): 250 - 280
  • Assessments

    Magnetic resonance imaging (MRI), Cystometric measurements, measure external urethral sphincter electromyography

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available
  • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available