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Erythropoietin-Derived Peptide Protects Against Acute Lung Injury After Rat Traumatic Brain Injury.

Y Liu | J Lu | X Wang | L Chen | S Liu | Z Zhang | W Yao
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2017

Traumatic brain injury (TBI) can be complicated by TBI-triggered acute lung injury (ALI), in which inflammation plays a central role. It has been reported that an Erythropoietin-derived peptide (pHBSP) was able to ameliorate TBI; however, its function in TBI-caused ALI has not been reported yet.

Pubmed ID: 28419985

TBI Model

  • Weight-drop model
  • Weight-drop contusion model

    • Animal Information

  • Species: rat
  • Strain: Lewis
  • Age (weeks): 8 - 9
  • Weight (grams): 350 - 400

    • Assessments

    Lowry’s method, Lung Wet/Dry Ratios, Hematoxylin and Eosin, Immunofluorescence, qRT-PCR, semiquantitative scoring system

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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