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Chronic Cortical Inflammation, Cognitive Impairment, and Immune Reactivity Associated with Diffuse Brain Injury Are Ameliorated by Forced Turnover of Microglia.

CE Bray | KG Witcher | D Adekunle-Adegbite | M Ouvina | M Witzel | E Hans | ZM Tapp | J Packer | E Goodman | F Zhao | T Chunchai | S O'Neil | SC Chattipakorn | J Sheridan | ON Kokiko-Cochran | C Askwith | JP Godbout
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2022 May 18

Pubmed ID: 35440489

TBI Model

  • Fluid percussion injury model
  • Midline Fluid percussion injury model

    • Animal Information

  • Species: mouse
  • Strain: C57BL/6
  • Age (weeks): 6 - 8
  • Weight (grams): No weight reported

    • Assessments

    Novel object location test, Novel object recognition test, qPCR, Compound action potential (CAP) recording, Immunohistochemistry (IHC)

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Contact Us

    Department of Neurosciences, School of Medicine

    University of California, San Diego





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