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Systemic Elevation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Is Associated with Protection against Visual, Motor, and Emotional Deficits in Mice following Closed-Head Mild Traumatic Brain Injury.

K Mondal | H Takahashi | J Cole | NA Del Mar | C Li | DJ Stephenson | J Allegood | LA Cowart | CE Chalfant | A Reiner | N Mandal
Molecular neurobiology | 2021 Nov

Pubmed ID: 34365584

TBI Model

  • Blast model
  • Blast injury model

    • Animal Information

  • Species: mouse
  • Strain: C57BL/6J
  • Age (weeks): No age reported
  • Weight (grams): No weight reported

    • Assessments

    Polyunsaturated Fatty Acids analysis, Sphingolipids analysis, Immunohistochemistry (IHC), Pavlovian fear conditioning, RT-PCR, Sphingomyelinase Assay, electroretinogram recording, open-field behavior assessment, optokinetic reflex measurement, tail suspension test

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    modified paintball gun

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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