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Left Ventricular Function in the Initial Period After Severe Traumatic Brain Injury in Swine.

A Adedipe | AS John | V Krishnamoorthy | X Wang | DT Steck | R Ferreira | N White | S Stern
Neurocritical care | 2022 Aug

Cardiac dysfunction is common in the days after severe traumatic brain injury (TBI) and may contribute to hypotension episodes, leading to worse outcomes. Little is known about cardiac function in the minutes and hours immediately following TBI. By using fluid percussion TBI in a swine model, we aimed to characterize the immediate post injury cardiac function.

Pubmed ID: 35314968

TBI Model

  • Fluid percussion injury model

    • Animal Information

  • Species: pig
  • Strain: Yorkshire
  • Age (weeks): No age reported
  • Weight (grams): 25000 - 30000

    • Assessments

    Cardiac output, Cerebral blood flow, renal blood flow, Doppler imaging, Pulsed wave Doppler measurements, Transesophageal echocardiography, blood gas, central venous pressure, intracranial pressure monitor

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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