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Labetalol Prevents Intestinal Dysfunction Induced by Traumatic Brain Injury.

Y Lang | F Fu | D Sun | C Xi | F Chen
PloS one | 2015

Beta-adrenergic blockade has been hypothesized to have a protective effect on intestinal dysfunction and increased intestinal permeability associated with the epinephrine surge after traumatic brain injury (TBI).

Pubmed ID: 26186619

TBI Model

  • Weight-drop model
  • Feeney’s Weight-drop model

    • Animal Information

  • Species: rat
  • Strain: Wister
  • Age (weeks): No age reported
  • Weight (grams): 200 - 250

    • Assessments

    Enzyme-linked immunosorbent assay (ELISA), Hematoxylin and Eosin, RT-PCR, Western blot, permeability assay

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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