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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://www.taconic.com/transgenic-mouse-model/apoe
Source Database: Taconic Biosciences
Affected Genes: |apolipoprotein E
Genomic Alteration: |targeted mutation 1; University of North Carolina
Availability: live
Synonyms: Apoe (ApoE) CONSTITUTIVE KNOCK OUT - C57BL/6 Background. B6.129P2-Apoe<tm1Unc>/Tac
Notes: gene symbol note: |apolipoprotein E; mutant strain|congenic strain: |Apoe
Proper citation: RRID:IMSR_TAC:APOE Copy
Issue
https://www.taconic.com/transgenic-mouse-model/hla-b7
Source Database: Taconic Biosciences
Affected Genes: beta-2 microglobulin|
Genomic Alteration: targeted mutation 1; University of North Carolina|transgene insertion 55; Hidde Ploegh
Availability: live
Notes: gene symbol note: beta-2 microglobulin|; unclassified|mutant stock: B2m|
Proper citation: RRID:IMSR_TAC:9661 Copy
Issue
http://www.taconic.com/transgenic-mouse-model/abb-knockouttransgenic-hla-dr4
Source Database: Taconic Biosciences
Affected Genes: histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; Michael J Grusby
Availability: live
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: H2-Ab1
Proper citation: RRID:IMSR_TAC:4149 Copy
Issue
https://brc.riken.jp/mus/RBRC04495
Source Database: RIKEN BioResource Research Center
Affected Genes: |TEK receptor tyrosine kinase|transgene insertion 1; Masashi Yanagisawa
Genomic Alteration: |endothelial-specific receptor tyrosine kinase|transgene insertion 1; Masashi Yanagisawa
Availability: embryo
Notes: gene symbol note: |TEK receptor tyrosine kinase|transgene insertion 1; Masashi Yanagisawa; mutant stock: |Tek|Tg(Tek-cre)1Ywa
Proper citation: RRID:IMSR_RBRC04495 Copy
Issue Issue
https://brc.riken.jp/mus/RBRC05131
Source Database: RIKEN BioResource Research Center
Affected Genes: interleukin 6
Genomic Alteration: targeted mutation 1; Manfred Kopf
Availability: embryo
Notes: gene symbol note: interleukin 6; mutant stock: Il6
Proper citation: RRID:IMSR_RBRC05131 Copy
Issue
https://brc.riken.jp/mus/RBRC02442
Source Database: RIKEN BioResource Research Center
Affected Genes: transgene insertion|Fas cell surface death receptor|lck proto-oncogene; Src family tyrosine kinase
Genomic Alteration: transgene insertion 1; Shigekazu Nagata|Fas (TNF receptor superfamily member)|lymphoproliferation|lymphocyte protein tyrosine kinase
Availability: embryo
Notes: gene symbol note: transgene insertion|Fas cell surface death receptor|lck proto-oncogene; Src family tyrosine kinase; mutant strain|congenic strain: Tg(dLck-Fas)|Fas|Lck
Proper citation: RRID:IMSR_RBRC02442 Copy
Issue
https://cardmice.com/rbase/strain?strainid=578
Source Database: Center for Animal Resources and Development
Affected Genes: poly (ADP-ribose) polymerase family; member 1
Genomic Alteration: targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani
Availability: embryo
Synonyms: 129(Cg)-Parp1<tm1Hsmm>/Hsmm
Notes: gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1
Proper citation: RRID:IMSR_CARD:578 Copy
Issue
https://cardmice.com/rbase/strain?strainid=579
Source Database: Center for Animal Resources and Development
Affected Genes: poly (ADP-ribose) polymerase family; member 1
Genomic Alteration: targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani
Availability: embryo
Synonyms: STOCK Parp1<tm1Hsmm>/Hsmm
Notes: gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1
Proper citation: RRID:IMSR_CARD:579 Copy
Issue
https://cardmice.com/rbase/strain?strainid=580
Source Database: Center for Animal Resources and Development
Affected Genes: poly (ADP-ribose) polymerase family; member 1
Genomic Alteration: targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani
Availability: embryo
Synonyms: B6.129S4(Cg)-Parp1<tm1Hsmm>/Hsmm
Notes: gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1
Proper citation: RRID:IMSR_CARD:580 Copy
Issue
https://cardmice.com/rbase/strain?strainid=583
Source Database: Center for Animal Resources and Development
Affected Genes: poly (ADP-ribose) polymerase family; member 1
Genomic Alteration: targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani
Availability: embryo
Synonyms: STOCK Parp1<tm1Hsmm>/3Hsmm
Notes: gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1
Proper citation: RRID:IMSR_CARD:583 Copy
Issue
https://brc.riken.jp/mus/RBRC06319
Source Database: RIKEN BioResource Research Center
Affected Genes: phenylalanine hydroxylase
Genomic Alteration: phenylalanine hydroxylase enu 2
Availability: embryo
Notes: gene symbol note: phenylalanine hydroxylase; mutant strain: Pah
Proper citation: RRID:IMSR_RBRC06319 Copy
Issue
https://brc.riken.jp/mus/RBRC06464
Source Database: RIKEN BioResource Research Center
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
Notes: gene symbol note: Fas cell surface death receptor; mutant strain: Fas
Proper citation: RRID:IMSR_RBRC06464 Copy
Issue Issue
https://www.jax.org/strain/005309
Source Database: JAX Mice and Services
Affected Genes: immunoglobulin heavy chain variable region|transgene insertion 2; Mark J Shlomchik|immunoglobulin heavy constant mu
Genomic Alteration: transgene insertion 2; Mark J Shlomchik|targeted mutation 1; University of Cologne
Availability: embryo
Synonyms: NODCaj.Cg-Igh-6<tm1Cgn> Tg(Igh-VB1-8/Igh-6)2Mjsk/FswJ. NOD.Cg-Igh-6<tm1Cgn> Tg(Igh-6/Igh-V186.2)2Xxx/XxxJ. NOD.Cg-Igh-6<tm1Cgn> Tg(Igh-6/Igh-V186.2)2Mjsk/FswJ. NOD.s+mIgM
Notes: gene symbol note: immunoglobulin heavy chain variable region|transgene insertion 2; Mark J Shlomchik|immunoglobulin heavy constant mu; coisogenic strain|mutant strain|congenic strain: Igh-V|Tg(Igh-VB1-8/Igh-6)2Mjsk|Ighm
Proper citation: RRID:IMSR_JAX:005309 Copy
Issue
https://www.jax.org/strain/005522
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 1; John F Elliot|insulin II
Genomic Alteration: transgene insertion 1; John F Elliot
Availability: embryo
Notes: gene symbol note: transgene insertion 1; John F Elliot|insulin II; coisogenic strain|mutant strain: Tg(Ins2*Y16A)1Ell|Ins2
Proper citation: RRID:IMSR_JAX:005522 Copy
Issue
https://www.jax.org/strain/005523
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 3; John F Elliot|insulin II
Genomic Alteration: transgene insertion 3; John F Elliot
Availability: embryo
Notes: gene symbol note: transgene insertion 3; John F Elliot|insulin II; coisogenic strain|mutant strain: Tg(Ins2*Y16A)3Ell|Ins2
Proper citation: RRID:IMSR_JAX:005523 Copy
Issue
https://www.jax.org/strain/005525
Source Database: JAX Mice and Services
Affected Genes: beta-galactosidase|insulin II|transgene insertion 3; John F Elliot|insulin I
Genomic Alteration: targeted mutation 1; Jacques Jami|transgene insertion 3; John F Elliot
Availability: embryo
Notes: gene symbol note: beta-galactosidase|insulin II|transgene insertion 3; John F Elliot|insulin I; mutant strain|congenic strain: lacZ|Ins2|Tg(Ins2*Y16A)3Ell|Ins1
Proper citation: RRID:IMSR_JAX:005525 Copy
Issue
https://www.jax.org/strain/005673
Source Database: JAX Mice and Services
Affected Genes: |MX dynamin-like GTPase 1|transgene insertion 1; University of Cologne
Genomic Alteration: transgene insertion 1; University of Cologne
Availability: sperm
Synonyms: Mx1-Cre(BALB/c)
Notes: gene symbol note: |MX dynamin-like GTPase 1|transgene insertion 1; University of Cologne; mutant strain|congenic strain: |Mx1|Tg(Mx1-cre)1Cgn
Proper citation: RRID:IMSR_JAX:005673 Copy
Issue
https://www.jax.org/strain/005983
Source Database: JAX Mice and Services
Affected Genes: intercellular adhesion molecule 1
Genomic Alteration: targeted mutation 1; Jose Carlos Gutierrez Ramos
Availability: sperm
Synonyms: NOD.Icam1. NOD.129S7(B6)-Icam1<tm1Bay>/MxJ. NOD.129S4(B6)-Icam1<tm1Jcgr>/MxJ
Notes: gene symbol note: intercellular adhesion molecule 1; mutant strain|congenic strain: Icam1
Proper citation: RRID:IMSR_JAX:005983 Copy
Issue
https://www.jax.org/strain/006021
Source Database: JAX Mice and Services
Affected Genes: CD2 molecule|major histocompatibility complex; class II; DQ alpha 1|major histocompatibility complex; class II; DQ beta 1|transgene insertion 1; John F Elliott|histocompatibility 2; class II antigen A; beta 1|CD4 molecule
Genomic Alteration: transgene insertion 1; John F Elliott|targeted mutation 1; Michael J Grusby
Availability: sperm
Synonyms: NOD.DQ8/Ab<0>. NOD.Cg-H2-Ab1<tm1Gru> Tg(CD2-CD4.HLA-DQA1.HLA-DQB1)1Ell/EllJ. NOD.AQ8/IAb. NOD.Cg-H2-Ab1<tm1Gru> Tg(CD2-CD4.HLA-DQA1*0301.HLA-DQB1*0302)1Ell/EllJ
Notes: gene symbol note: CD2 molecule|major histocompatibility complex; class II; DQ alpha 1|major histocompatibility complex; class II; DQ beta 1|transgene insertion 1; John F Elliott|histocompatibility 2; class II antigen A; beta 1|CD4 molecule; mutant strain|congenic strain: CD2|HLA-DQA1|HLA-DQB1|Tg(CD2-CD4;HLA-DQA1;HLA-DQB1)1Ell|H2-Ab1|CD4
Proper citation: RRID:IMSR_JAX:006021 Copy
Issue
https://www.jax.org/strain/006023
Source Database: JAX Mice and Services
Affected Genes: transgene insertion N8; John F Elliott|CD4 molecule|major histocompatibility complex; class II; DQ alpha 1|major histocompatibility complex; class II; DQ beta 1|histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: transgene insertion N8; John F Elliott|targeted mutation 1; Michael J Grusby
Availability: embryo
Synonyms: NOD.Cg-H2-Ab1<tm1Gru> Tg(CD4.HLA-DQA1*0102.HLA-DQB1*0602)1Ell/EllJ. NOD.Cg-H2-Ab1<tm1Gru> Tg(CD4.HLA-DQA1.HLA-DQB1)N8Ell/EllJ. NOD.Cg-H2-Ab1<tm1Gru> Tg(CD4. HLA-DQA*0102. HLA-DQB*0602)1Ell/EllJ. NOD.Cg-Ab1<tm1Gru> Tg(CD4. HLA-DQA*0102. HLA-DQB*0602)1Ell/EllJ
Notes: gene symbol note: transgene insertion N8; John F Elliott|CD4 molecule|major histocompatibility complex; class II; DQ alpha 1|major histocompatibility complex; class II; DQ beta 1|histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: Tg(CD4;HLA-DQA1;HLA-DQB1)N8Ell|CD4|HLA-DQA1|HLA-DQB1|H2-Ab1
Proper citation: RRID:IMSR_JAX:006023 Copy
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