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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040830
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001178(egl-9)
Genomic Alteration: WBGene00001178(egl-9)
Availability: available
References:
Synonyms: iaIs7 IV; egl-9(gk277) V.
Alternate IDs: WB-STRAIN:ZG444, CGC_ZG444
Notes: iaIs7 contains [nhr-57p::GFP + unc-119(+)]. nhr-57p::GFP is expressed at low levels. Superficially wild-type. Published in Shao, Zhang, and Powell-Coffman Genetics (2009).
Proper citation: RRID:WB-STRAIN:WBStrain00040830 Copy
http://www.wormbase.org/db/get?name=WBStrain00040847
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006833(unc-108)
Genomic Alteration: WBGene00006833(unc-108)
Availability: available
References:
Synonyms: unc-108(n3263) I.
Alternate IDs: WB-STRAIN:ZH382, CGC_ZH382
Notes: Made_by: P Mangahas & Z Zhou|"Recessive Unc. Recessive apoptotic cell removal defect. Recessive phagosome maturation defect (inefficient and prolonged phagosome maturation process in embryos). Reference: Mangahas PM, Yu X, and Zhou Z. J Cell Biol. 2008 Jan 28;180(2):357-73."
Proper citation: RRID:WB-STRAIN:WBStrain00040847 Copy
http://www.wormbase.org/db/get?name=WBStrain00040848
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006762(unc-25)
Genomic Alteration: WBGene00006762(unc-25)
Availability: available
References:
Synonyms: hpIs3 X.
Alternate IDs: WB-STRAIN:ZM54, CGC_ZM54
Notes: hpIs3 [unc-25p::syd-2::GFP] X. GFP is expressed in small puncta along ventral and dorsal cords; bright perinuclear staining in DD and VD cell bodies. hpIs3/+ and hpIs3 males have reduced GFP levels in cell bodies. Reference: Yeh E, et al. J Neurosci. 2005 Apr 13;25(15):3833-41.|"Supplementary_genotype hpIs3 [punc-25::SYD-2::GFP; lin-15+] X"
Proper citation: RRID:WB-STRAIN:WBStrain00040848 Copy
http://www.wormbase.org/db/get?name=WBStrain00040843
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001556(gcy-36)
Genomic Alteration: WBGene00001556(gcy-36)
Availability: available
References:
Synonyms: iaIs22.
Alternate IDs: WB-STRAIN:ZG629, CGC_ZG629
Notes: iaIs22 [gcy-36p::GFP + unc-119(+)]. gcy-36::GFP is consistently expressed in AQR, PQR, URXL and URXR neurons.
Proper citation: RRID:WB-STRAIN:WBStrain00040843 Copy
http://www.wormbase.org/db/get?name=WBStrain00040842
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000521(cky-1)
Genomic Alteration: WBGene00000521(cky-1)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZG628
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040842 Copy
http://www.wormbase.org/db/get?name=WBStrain00040845
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001556(gcy-36)
Genomic Alteration: WBGene00001556(gcy-36)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZG631
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040845 Copy
http://www.wormbase.org/db/get?name=WBStrain00040844
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001555(gcy-35)
Genomic Alteration: WBGene00001555(gcy-35)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZG630
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040844 Copy
http://www.wormbase.org/db/get?name=WBStrain00040841
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001552(gcy-32)
Genomic Alteration: WBGene00001552(gcy-32)
Availability: available
References:
Synonyms: iaIs19.
Alternate IDs: WB-STRAIN:ZG611, CGC_ZG611
Notes: iaIs19 [gcy-32p::GFP + unc-119(+)]. Expression of gcy-32::GFP is consistenly observed in AQR, PQR, and URX neurons.
Proper citation: RRID:WB-STRAIN:WBStrain00040841 Copy
http://www.wormbase.org/db/get?name=WBStrain00040817
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZD1169
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040817 Copy
http://www.wormbase.org/db/get?name=WBStrain00040819
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00015920(eif-3.L)
Genomic Alteration: WBGene00015920(eif-3.L)
Availability: available
References:
Synonyms: eif-3.L(qd310) II.
Alternate IDs: WB-STRAIN:ZD1258, CGC_ZD1258
Notes: C17G10.9 Increased lifespan and enhanced resistance to endoplasmic reticulum (ER) stress, independent of IRE-1-XBP-1, ATF-6, and PEK-1. Reference: Cattie DJ, et al. PLoS Genet. 2016 Sep 30;12(9):e1006326.|"Mutagen: n/a"
Proper citation: RRID:WB-STRAIN:WBStrain00040819 Copy
http://www.wormbase.org/db/get?name=WBStrain00040813
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000223(atf-7)
Genomic Alteration: WBGene00000223(atf-7)
Availability: available
References:
Synonyms: atf-7(qd22); agIs219[T24B8.5p::GFP+ttx-3p::GFP]
Alternate IDs: WB-STRAIN:ZD442, CGC_ZD442
Notes: agIs219 [T24B8.5p::GFP::unc-54-3' UTR + ttx-3p::GFP::unc-54-3' UTR] III. Enhanced susceptibility to pathogens. References: Shivers RP, et al. PLoS Genet. 2010 Apr 1;6(4):e1000892. Shivers RP, et al. Cell Host Microbe. 2009 Oct 22;6(4):321-30.
Proper citation: RRID:WB-STRAIN:WBStrain00040813 Copy
http://www.wormbase.org/db/get?name=WBStrain00040812
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000223(atf-7)|WBGene00004758(sek-1)
Genomic Alteration: WBGene00000223(atf-7), WBGene00004758(sek-1)
Availability: available
References:
Synonyms: agIs219 atf-7(qd22qd130) III; sek-1(km4) X.
Alternate IDs: WB-STRAIN:ZD340, CGC_ZD340
Notes: agIs219 [T24B8.5p::GFP::unc-54-3' UTR + ttx-3p::GFP::unc-54-3' UTR] III. atf-7(qd22 qd130) suppresses increased pathogen susceptibiliy (Esp) of sek-1(km4). References: Shivers RP, et al. PLoS Genet. 2010 Apr 1;6(4):e1000892.
Proper citation: RRID:WB-STRAIN:WBStrain00040812 Copy
http://www.wormbase.org/db/get?name=WBStrain00040896
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00023497(lin-15B)|WBGene00023498(lin-15A)
Genomic Alteration: WBGene00023497(lin-15B), WBGene00023498(lin-15A)
Availability: available
References:
Synonyms: lin-15B&lin-15A(n765) X; zwEx114.
Alternate IDs: WB-STRAIN:ZW294, CGC_ZW294
Notes: zwEx114 [inx-14p::GFP + lin-15(+)]. Pick non-Muv to maintain. Reference: Altun et al. Dev Dyn 238:1936-50 (2009).
Proper citation: RRID:WB-STRAIN:WBStrain00040896 Copy
http://www.wormbase.org/db/get?name=WBStrain00040824
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001851(hif-1)
Genomic Alteration: WBGene00001851(hif-1)
Availability: available
References:
Synonyms: hif-1(ia4) V.
Alternate IDs: WB-STRAIN:ZG31, CGC_ZG31
Notes: Healthy and fertile in standard lab conditions, but unable to adapt to 1% oxygen. When hif-1(+) animals are incubated in1% oxygen, >94% will complete embryogenesis and larval development. In contrast, hif-1(ia4) mutants exhibit 66% embryonic lethality and 9% larval lethality in 1% oxygen. The requirement of hif-1 is alleviated if the oxygen level is increased to 2%. The ia4 mutation is a 1231 bp deletion of the second, third, and fourth exons, which encode much of the helix-loop-helix and PAS domains. Analysis of ESTs suggests that there are at least 4 alternatively spliced hif-1 transcripts. The ia4 deletion introduces a frameshift and a premature stop in the three longest forms.|"Made_by: Jiang/Powell-Coffman"|"Reference WBPaper00059755 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype hif-1(ia4), RE666 ire-1(v33), xbp-1(tm2482)"
Proper citation: RRID:WB-STRAIN:WBStrain00040824 Copy
http://www.wormbase.org/db/get?name=WBStrain00040820
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: eif-2a(qd338) I.
Alternate IDs: WB-STRAIN:ZD1866, CGC_ZD1866
Notes: Y37E3.10. qd338 disrupts Ser49 phosphorylation site; suppresses daf-28(sa191) constitutive dauer entry phenotype. Reference: Kulalert W, et al. Genetics 2017. In press.
Proper citation: RRID:WB-STRAIN:WBStrain00040820 Copy
http://www.wormbase.org/db/get?name=WBStrain00040823
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000096(ahr-1)
Genomic Alteration: WBGene00000096(ahr-1)
Availability: available
References:
Synonyms: ahr-1(ia3) I.
Alternate IDs: WB-STRAIN:ZG24, CGC_ZG24
Notes: Homozygous viable with neuronal defects.|"WBStrain provided so WBPaper00060797 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00040823 Copy
http://www.wormbase.org/db/get?name=WBStrain00040822
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00009956(F53B2.5)
Genomic Alteration: WBGene00009956(F53B2.5)
Availability: available
References:
Synonyms: F53B2.5(ok226)
Alternate IDs: WB-STRAIN:ZE1, CGC_ZE1
Notes: Homozygotes are viable and do not show any gross abnormalities. Grows normally at all temperatures. Deletion removes 1505 bp including the first 4 exons.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00040822 Copy
http://www.wormbase.org/db/get?name=WBStrain00040917
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00002978(lev-11)
Genomic Alteration: WBGene00002978(lev-11)
Availability: available
References:
Synonyms: lev-11(x1) I.
Alternate IDs: WB-STRAIN:ZZ1, CGC_ZZ1
Notes: Levamisole resistant. Twitcher.|"Made_by: J Lewis"
Proper citation: RRID:WB-STRAIN:WBStrain00040917 Copy
http://www.wormbase.org/db/get?name=WBStrain00040919
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006797(unc-63)
Genomic Alteration: WBGene00006797(unc-63)
Availability: available
References:
Synonyms: unc-63(x13) I.
Alternate IDs: WB-STRAIN:ZZ13, CGC_ZZ13
Notes: Levamisole resistant Unc. Tends to accumulate eggs. M-MATING+++ 10-30%WT. pka lev-7.|"Made_by: Lewis J"
Proper citation: RRID:WB-STRAIN:WBStrain00040919 Copy
http://www.wormbase.org/db/get?name=WBStrain00040918
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00002978(lev-11)
Genomic Alteration: WBGene00002978(lev-11)
Availability: available
References:
Synonyms: lev-11(x12) I.
Alternate IDs: WB-STRAIN:ZZ12, CGC_ZZ12
Notes: Levamisole resistant twitcher. Weakly semi-dominant. M-MATING++ 1-10%WT.|"Made_by: Lewis J"
Proper citation: RRID:WB-STRAIN:WBStrain00040918 Copy
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