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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040710
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: ypIn2 II.
Alternate IDs: WB-STRAIN:YA1197, CGC_YA1197
Notes: ypIn2 [daz-1p::pot-1::mCherry::tbb-2 3'UTR + Cbr-unc-119(+)] II. Single copy MosSCI insertion at ttTi5605 locus on LG II. Reference: Shtessel L, et al. G3 (Bethesda). 2013 Feb;3(2):305-13.
Proper citation: RRID:WB-STRAIN:WBStrain00040710 Copy
http://www.wormbase.org/db/get?name=WBStrain00040798
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZB1336
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040798 Copy
http://www.wormbase.org/db/get?name=WBStrain00040712
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00007395(dcar-1)
Genomic Alteration: WBGene00007395(dcar-1)
Availability: available
References:
Synonyms: dcar-1(tm2484) V.
Alternate IDs: WB-STRAIN:YC307, CGC_YC307
Notes: Defective avoidance to water-soluble repellent. Reference: Aoki R., et al. J Neurosci. 2011 Nov 16;31(46):16603-10.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00040712 Copy
http://www.wormbase.org/db/get?name=WBStrain00040797
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001612(glr-1)|WBGene00001613(glr-2)|WBGene00001621(glt-3)
Genomic Alteration: WBGene00001612(glr-1), WBGene00001613(glr-2), WBGene00001621(glt-3)
Availability: unknown
References:
Synonyms: glr-2(ak10) glr-1(ky176) III; glt-3(bz34) IV; nuIs5 V.
Alternate IDs: WB-STRAIN:ZB1335
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040797 Copy
http://www.wormbase.org/db/get?name=WBStrain00040729
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001072(dpy-10)|WBGene00003821(nst-1)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00003821(nst-1)
Availability: available
References:
Synonyms: nst-1(vr6)/mIn1 [mIs14 dpy-10(e128)] II.
Alternate IDs: WB-STRAIN:YL108, CGC_YL108
Notes: mIn1 carries a GFP marker. Heterozygotes are GFP+ and segregate heterozygotes (wild-type GFP+), mIn1 homozygotes (Dpy GFP+) and vr6 homozygotes (GFP- and arrest as L1/L2 larvae). Maintain by picking GFP+ and checking for proper segregation of progeny. Reference: Kudron et al. (2008) PLos Genet 4(8):e1000181.
Proper citation: RRID:WB-STRAIN:WBStrain00040729 Copy
http://www.wormbase.org/db/get?name=WBStrain00040728
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000272(bro-1)
Genomic Alteration: WBGene00000272(bro-1)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:YK149
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040728 Copy
http://www.wormbase.org/db/get?name=WBStrain00040722
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000235(baf-1)|WBGene00000254(bli-4)|WBGene00001159(eff-1)
Genomic Alteration: WBGene00000235(baf-1), WBGene00000254(bli-4), WBGene00001159(eff-1)
Availability: available
References:
Synonyms: baf-1(gk324) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); eff-1(ok1021) II; syIs78.
Alternate IDs: WB-STRAIN:YG1046, CGC_YG1046
Notes: syIs78 [ajm-1::GFP + unc-119(+)] is probably on LG I (not on II, III, V or X). Heterozygotes are slow-growing DpyUnc with cell fusion problems and pharyngeal GFP signal. Segregates arrested hT2 aneuploids, and non-GFP DpyUnc gk324 homozygotes (Sterile, Dpy and Unc). All worms express ajm-1::GFP(Junction Associated Protein). qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter driving GFP in the intestine, and is homozygous lethal.
Proper citation: RRID:WB-STRAIN:WBStrain00040722 Copy
http://www.wormbase.org/db/get?name=WBStrain00040724
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000254(bli-4)|WBGene00000386(cdc-25.1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00000386(cdc-25.1)
Availability: available
References:
Synonyms: cdc-25.1(bn115) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:YHS2, CGC_YHS2
Notes: Homozygous sterile deletion balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP bn115 homozygotes (sterile). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Kim J, et al. (2009) Mol Cell 28:43-8.
Proper citation: RRID:WB-STRAIN:WBStrain00040724 Copy
http://www.wormbase.org/db/get?name=WBStrain00040723
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00012132(ifta-2)
Genomic Alteration: WBGene00012132(ifta-2)
Availability: available
References:
Synonyms: ifta-2(tm1724) IV.
Alternate IDs: WB-STRAIN:YH461, CGC_YH461
Notes: Extended life span. daf-d.
Proper citation: RRID:WB-STRAIN:WBStrain00040723 Copy
http://www.wormbase.org/db/get?name=WBStrain00040720
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000235(baf-1)|WBGene00000254(bli-4)|WBGene00001578(ges-1)|WBGene00003052(lmn-1)|WBGene00003514(myo-2)|WBGene00003983(pes-10)
Genomic Alteration: WBGene00000235(baf-1), WBGene00000254(bli-4), WBGene00001578(ges-1), WBGene00003052(lmn-1), WBGene00003514(myo-2), WBGene00003983(pes-10)
Availability: available
References:
Synonyms: baf-1(gk324) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); ccIs4810 X.
Alternate IDs: WB-STRAIN:YG1021, CGC_YG1021
Notes: ccIs4810 [(pJKL380.4) lmn-1p::lmn-1::GFP::lmn-1 3'utr + (pMH86) dpy-20(+)] X. Heterozygotes are WT with pharyngeal GFP signal, and segregate arrested hT2 aneuploids, non-GFP gk324 homozygotes (Sterile and Unc). All worms express Cel-lamin::GFP (lmn-1 gene is expressed at the nuclear periphery). qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter driving GFP in the intestine, and is homozygous lethal.
Proper citation: RRID:WB-STRAIN:WBStrain00040720 Copy
http://www.wormbase.org/db/get?name=WBStrain00040770
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00014208(znfx-1)
Genomic Alteration: WBGene00014208(znfx-1)
Availability: available
References:
Synonyms: znfx-1(gg561) II.
Alternate IDs: WB-STRAIN:YY996, CGC_YY996
Notes: Heritable RNAi defective, germline immortality. Reference: Wan G, et al. Nature. 2018 May;557(7707):679-683.|"Supplementary_genotype znfx-1(gg561)"
Proper citation: RRID:WB-STRAIN:WBStrain00040770 Copy
http://www.wormbase.org/db/get?name=WBStrain00040777
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006748(unc-8)
Genomic Alteration: WBGene00006748(unc-8)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZB167
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040777 Copy
http://www.wormbase.org/db/get?name=WBStrain00040776
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003168(mec-4)
Genomic Alteration: WBGene00003168(mec-4)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZB154
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040776 Copy
http://www.wormbase.org/db/get?name=WBStrain00040778
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000952(del-1)
Genomic Alteration: WBGene00000952(del-1)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZB170
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040778 Copy
http://www.wormbase.org/db/get?name=WBStrain00040772
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00014208(znfx-1)
Genomic Alteration: WBGene00014208(znfx-1)
Availability: available
References:
Synonyms: znfx-1(gg634[HA::tagRFP::znfx-1]) II.
Alternate IDs: WB-STRAIN:YY1446, CGC_YY1446
Notes: Alt Genotype: znfx-1(gg634[HA::tagRFP::znfx-1]) II|"Contains Construct ref. Wan G. et al. Nature 2018"|"HA::tagRFP inserted into endogenous znfx-1 locus using CRISPR/Cas9 engineering. Reference: Wan G, et al. Nature. 2018 May;557(7707):679-683."|"N-terminal HA::tagRFP tag on endogenous znfx-1"
Proper citation: RRID:WB-STRAIN:WBStrain00040772 Copy
http://www.wormbase.org/db/get?name=WBStrain00040774
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003168(mec-4)
Genomic Alteration: WBGene00003168(mec-4)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZB2
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040774 Copy
http://www.wormbase.org/db/get?name=WBStrain00040708
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001998(hpr-17)
Genomic Alteration: WBGene00001998(hpr-17)
Availability: unknown
References:
Synonyms: hpr-17(tm1579) II.
Alternate IDs: WB-STRAIN:YA1080
Notes: Defective in responding to ionizing radiation or hydroxyurea. Defective for telomerase activity in vivo. Freeze immediately and thaw when needed; becomes inviable if maintained as a homozygote. Received new stock 11/2008.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00040708 Copy
http://www.wormbase.org/db/get?name=WBStrain00040707
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006618(trt-1)
Genomic Alteration: WBGene00006618(trt-1)
Availability: available
References:
Synonyms: trt-1(ok410) I.
Alternate IDs: WB-STRAIN:YA1059, CGC_YA1059
Notes: Becomes very sick if starved for extended periods of time or if frozen and thawed repeatedly.|"Becomes very sick if starved for extended periods of time or if frozen and thawed repeatedly. Primer sequences provided by the C. elegans Reverse Genetics Core Facility for ok410 are: Outer Left Sequence: AAGACTGTCAGCTGGTGGGT. Outer Right Sequence: TTAGCCTTACATTGCCGCTT. Inner Left Sequence: TCATGCGCAACATCTAAAGC. Inner Right Sequence: CGAATAAAGCAATTTCCCGA. Inner primer WT PCR product: 2825."
Proper citation: RRID:WB-STRAIN:WBStrain00040707 Copy
http://www.wormbase.org/db/get?name=WBStrain00040709
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00045237(mrt-1)
Genomic Alteration: WBGene00045237(mrt-1)
Availability: available
References:
Synonyms: mrt-1(tm1354) I.
Alternate IDs: WB-STRAIN:YA1116, CGC_YA1116
Notes: Null allele. Mortal germline. Progressive telomere shortening due to telomerase dysfunction. Hypersensitive to DNA interstrand crosslinking agents. This strain will becomce sterile after propagating 10-20 generations. mrt-1 mutants can be rejuvenated by outcrossing. Reference: Meier B, et al. EMBO J. 2009 Nov 18;28(22):3549-63.|"Null allele. Mortal germline. Progressive telomere shortening due to telomerase dysfunction. Hypersensitive to DNA interstrand crosslinking agents. This strain will become sterile after propagating 10-20 generations. mrt-1 mutants can be rejuvenated by outcrossing. Reference: Meier B, et al. EMBO J. 2009 Nov 18;28(22):3549-63."
Proper citation: RRID:WB-STRAIN:WBStrain00040709 Copy
http://www.wormbase.org/db/get?name=WBStrain00040704
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001851(hif-1)
Genomic Alteration: WBGene00001851(hif-1)
Availability: available
References:
Synonyms: hif-1(ia4) V; yakEx146.
Alternate IDs: WB-STRAIN:XZ2085, CGC_XZ2085
Notes: yakEx146 [vha-6p::hif-1(cDNA) + dpy-7p::hif-1(cDNA) + rab-3p::hif-1(cDNA) + myo-2p::mCherry]. Pick animals with red pharynx to maintain. HIF-1 expressed from pan-neuronal-, hypodermal-, and intestinal-specific promoters in hif-1 mutant background for tissue-specific rescuing experiments. yakEx146 does not rescue lethality in hif-1 mutant animals exposed to 50ppm hydrogen sulfide. Reference: Topalidou I & and Miller DL. bioRxiv 174581; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00040704 Copy
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