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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040767
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000939(dcr-1)
Genomic Alteration: WBGene00000939(dcr-1)
Availability: available
References:
Synonyms: dcr-1(mg375) III.
Alternate IDs: WB-STRAIN:YY470, CGC_YY470
Notes: Enhanced RNAi response. Sterile at 25 C. Outcrossed from YY11; wild-type for mut-16. Superficially wild-type.
Proper citation: RRID:WB-STRAIN:WBStrain00040767 Copy
http://www.wormbase.org/db/get?name=WBStrain00040800
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00021316(Y32H12A.8)
Genomic Alteration: WBGene00021316(Y32H12A.8)
Availability: available
References:
Synonyms: Y32H12A.8(tm422) III.
Alternate IDs: WB-STRAIN:ZB1748, CGC_ZB1748
Notes: Made_by:
Proper citation: RRID:WB-STRAIN:WBStrain00040800 Copy
http://www.wormbase.org/db/get?name=WBStrain00040762
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00011333(nrde-2)
Genomic Alteration: WBGene00011333(nrde-2)
Availability: available
References:
Synonyms: nrde-2(gg91) II.
Alternate IDs: WB-STRAIN:YY186, CGC_YY186
Notes: T to A substitution at position 129 and Y to stop at position 24 in exon 2. Reference: GuangS, et al. Nature. 2010 Jun 24;465(7301):1097-101.
Proper citation: RRID:WB-STRAIN:WBStrain00040762 Copy
http://www.wormbase.org/db/get?name=WBStrain00040737
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; vrIs64.
Alternate IDs: WB-STRAIN:YL416, CGC_YL416
Notes: Made_by: Reinke Lab|"vrIs64 [ges-1p::hpl-2::GFP::FLAG::hpl-2 3'UTR + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00040737 Copy
http://www.wormbase.org/db/get?name=WBStrain00040738
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; vrIs65.
Alternate IDs: WB-STRAIN:YL418, CGC_YL418
Notes: Made_by: Reinke Lab|"vrIs65 [ges-1p::efl-1::GFP::FLAG::efl-1 3'UTR + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00040738 Copy
http://www.wormbase.org/db/get?name=WBStrain00040733
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; vrIs48.
Alternate IDs: WB-STRAIN:YL390, CGC_YL390
Notes: Made_by: Reinke Lab|"Modern strain"|"vrIs48 [pie-1p::dpl-1::GFP::FLAG::dpl-1 3'UTR + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00040733 Copy
http://www.wormbase.org/db/get?name=WBStrain00040734
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; vrIs55.
Alternate IDs: WB-STRAIN:YL398, CGC_YL398
Notes: Made_by: Reinke Lab|"vrIs55 [ges-1p::lin-35::GFP::FLAG::lin-35 3'UTR + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00040734 Copy
http://www.wormbase.org/db/get?name=WBStrain00040731
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; vrEx6.
Alternate IDs: WB-STRAIN:YL206, CGC_YL206
Notes: vrEx6 [nst-1p::nst-1::GFP::nst-1 3' UTR + unc-119(+)]. Stable array; high transmission rate and low percentage of mosaicism. Maintain by picking wild-type. Reference: Kudron et al. (2008) PLos Genet 4(8):e1000181.
Proper citation: RRID:WB-STRAIN:WBStrain00040731 Copy
http://www.wormbase.org/db/get?name=WBStrain00040748
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)|WBGene00018294(atg-18)
Genomic Alteration: WBGene00006843(unc-119), WBGene00018294(atg-18)
Availability: available
References:
Synonyms: unc-119(ed3) III; atg-18(gk378) V; wfIs232.
Alternate IDs: WB-STRAIN:YQ243, CGC_YQ243
Notes: wfIs232 [app-1p::mCherry::H2B::unc-54 + unc-119(+)]. mCherry::H2B expression in the nuclei of intestinal cells. YQ243 can serve as a control strain for YQ95. Reference: Chen HD, et al. Autophagy. 2016 Nov 22:1-15.
Proper citation: RRID:WB-STRAIN:WBStrain00040748 Copy
http://www.wormbase.org/db/get?name=WBStrain00040747
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)|WBGene00018294(atg-18)
Genomic Alteration: WBGene00006843(unc-119), WBGene00018294(atg-18)
Availability: available
References:
Synonyms: unc-119(ed3) III; atg-18(gk378) V; wfIs120.
Alternate IDs: WB-STRAIN:YQ95, CGC_YQ95
Notes: wfIs120 [app-1p::atg-18::unc-54 + unc-119(+)]. Intestine-specific promoter app-1 drives atg-18 expression in the atg-18(gk378) mutant background, providing rescue in intestinal cells. Reference: Chen HD, et al. Autophagy. 2016 Nov 22:1-15.
Proper citation: RRID:WB-STRAIN:WBStrain00040747 Copy
http://www.wormbase.org/db/get?name=WBStrain00040749
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000366(cbp-1)|WBGene00001077(dpy-18)|WBGene00001078(dpy-19)|WBGene00001609(glp-1)
Genomic Alteration: WBGene00000366(cbp-1), WBGene00001077(dpy-18), WBGene00001078(dpy-19), WBGene00001609(glp-1)
Availability: available
References:
Synonyms: cbp-1(bm1) dpy-18(e364)/qC1 [dpy-19(e1259) glp-1(q339)] III.
Alternate IDs: WB-STRAIN:YS2, CGC_YS2
Notes: Heterozygotes are WT and segregate WT, Dpy Steriles and dead eggs. cbp-1 is embyronic lethal. ys2 is an internal deletion in cbp-1. NOTE: THIS STRAIN WAS FORMERLY IDENTIFIED AS HA1000 cbp-1(ys2) dpy-18(e364)/qC1 dpy-19(e1259) glp-1(q339) III. The strain name and allele were corrected per Anne Hart, 2010.
Proper citation: RRID:WB-STRAIN:WBStrain00040749 Copy
http://www.wormbase.org/db/get?name=WBStrain00040744
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00018636(oef-1)
Genomic Alteration: WBGene00018636(oef-1)
Availability: available
References:
Synonyms: oef-1(vr25) IV.
Alternate IDs: WB-STRAIN:YL585, CGC_YL585
Notes: Made_by: Catherine McManus|"vr25 is a Crispr/Cas9-induced 56 bp deletion in exon 2 of oef-1/F49E8.2 causing a frameshift and presumptive null allele. Accelerated rate of germ cell progression, precocious Z2/Z3 division in L1s, increased brood size and sperm generation, and increased germline apoptosis. Reference: McManus, CE & Reinke, V. Genetics. 2017; https:"
Proper citation: RRID:WB-STRAIN:WBStrain00040744 Copy
http://www.wormbase.org/db/get?name=WBStrain00040745
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00002783(let-607)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00002783(let-607), WBGene00006843(unc-119)
Availability: available
References:
Synonyms: let-607(tm1423) I; unc-119(ed3) III; vrIs121.
Alternate IDs: WB-STRAIN:YL651, CGC_YL651
Notes: vrIs121 [let-607(fosmid)::GFP + unc-119(+)]. let-607 locus in fosmid tagged at the carboxy-terminus with GFP. Derived by crossing the LET-607::GFP transgenic strain (YL529) to let-607(tm1423) mutants. vrIs121 transgene rescues the lethal mutant phenotype of let-607(tm1423) homozygous mutants. Reference: Weicksel SE, et al. Development. 2016 Oct 1;143(19):3540-3548.
Proper citation: RRID:WB-STRAIN:WBStrain00040745 Copy
http://www.wormbase.org/db/get?name=WBStrain00040742
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; vrIs83.
Alternate IDs: WB-STRAIN:YL448, CGC_YL448
Notes: Made_by: Reinke Lab|"Modern strain"|"vrIs83 [ges-1p::dpl-1::GFP::FLAG::dpl-1 3'UTR + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00040742 Copy
http://www.wormbase.org/db/get?name=WBStrain00040718
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000235(baf-1)|WBGene00000254(bli-4)|WBGene00001578(ges-1)|WBGene00002246(lag-2)|WBGene00003514(myo-2)|WBGene00003983(pes-10)
Genomic Alteration: WBGene00000235(baf-1), WBGene00000254(bli-4), WBGene00001578(ges-1), WBGene00002246(lag-2), WBGene00003514(myo-2), WBGene00003983(pes-10)
Availability: available
References:
Synonyms: baf-1(gk324) III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); qIs19 V.
Alternate IDs: WB-STRAIN:YG1011, CGC_YG1011
Notes: qIs19 [lag-2p::GFP::unc-54 3'UTR + rol-6(su1006)] V. Heterozygotes are Rollers with pharyngeal GFP signal, and segregate arrested hT2 aneuploids, and non-GFP gk324 homozygotes (Sterile and Unc). All worms express lag-2p::GFP at the distal tip cells. qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter driving GFP in the intestine, and is homozygous lethal.
Proper citation: RRID:WB-STRAIN:WBStrain00040718 Copy
http://www.wormbase.org/db/get?name=WBStrain00040715
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001072(dpy-10)|WBGene00016151(smc-5)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00016151(smc-5)
Availability: available
References:
Synonyms: smc-5(tm2868)/mIn1 [mIs14 dpy-10(e128)] II.
Alternate IDs: WB-STRAIN:YE59, CGC_YE59
Notes: Homozygous viable mutation balanced by GFP- and dpy-10-marked inversion. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP, Dpy bright GFP (mIn1 homozygotes), and non-GFP tm2868 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain. tm2868 homozygotes are morphologically wild-type but show ~30% reduction in fertilized eggs and a trans-generational increase in sterility. Maintain under normal conditions. Reference: Bickel JS, et al. PLoS Genet. 2010 Jul 22;6(7):e1001028.|"Made_by: Jeremy Bickel"
Proper citation: RRID:WB-STRAIN:WBStrain00040715 Copy
http://www.wormbase.org/db/get?name=WBStrain00040714
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001072(dpy-10)|WBGene00010056(smc-6)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00010056(smc-6)
Availability: available
References:
Synonyms: smc-6(ok3294)/mIn1 [mIs14 dpy-10(e128)] II.
Alternate IDs: WB-STRAIN:YE58, CGC_YE58
Notes: Homozygous viable mutation balanced by GFP- and dpy-10-marked inversion. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP, Dpy bright GFP (mIn1 homozygotes), and non-GFP ok3294 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain. ok3294 homozygotes are morphologically wild-type but show ~30% reduction in fertilized eggs and a trans-generational increase in sterility. Maintain under normal conditions. Reference: Bickel JS, et al. PLoS Genet. 2010 Jul 22;6(7):e1001028.|"Made_by: Jeremy Bickel"
Proper citation: RRID:WB-STRAIN:WBStrain00040714 Copy
http://www.wormbase.org/db/get?name=WBStrain00040716
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: ([baf-1p::GFP::lmn-1 L535P unc-119(+)]; unc-119 (ed3))
Alternate IDs: WB-STRAIN:YG499
Notes: Created as part of the paper markup
Proper citation: RRID:WB-STRAIN:WBStrain00040716 Copy
http://www.wormbase.org/db/get?name=WBStrain00040793
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001620(glt-1)|WBGene00001621(glt-3)
Genomic Alteration: WBGene00001620(glt-1), WBGene00001621(glt-3)
Availability: available
References:
Synonyms: glt-3(bz34) IV; glt-1(ok206) X.
Alternate IDs: WB-STRAIN:ZB1106, CGC_ZB1106
Notes: Reference: Mano et al. (2007) J Biol Chem 282(47):34412-9.
Proper citation: RRID:WB-STRAIN:WBStrain00040793 Copy
http://www.wormbase.org/db/get?name=WBStrain00040792
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:ZB1105
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040792 Copy
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