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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040650
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001332(eri-1)|WBGene00003004(lin-15)|WBGene00004323(rde-1)|WBGene00023497(lin-15B)
Genomic Alteration: WBGene00001332(eri-1), WBGene00003004(lin-15), WBGene00004323(rde-1), WBGene00023497(lin-15B)
Availability: available
References:
Synonyms: wpIs36 I; wpSi1 II; eri-1(mg366) IV; rde-1(ne219) V; lin-15B(n744) X.
Alternate IDs: WB-STRAIN:XE1375, CGC_XE1375
Notes: Made_by: C. Firnhaber|"Mutagen:TMP+UV"|"Mutagen:TMP/UV"|"wpIs36 [unc-47p::mCherry] I. wpSi1 [unc-47p::rde-1::SL2::sid-1 + Cbr-unc-119(+)] II. Maintain at 15-20C, sterile at 25C. GABAergic neuron-specific RNAi strain. Sensitivity to feeding RNAi is limited to the GABAergic neurons; all other tissues are resistant to RNAi. Superficially wild type with mCherry fluorescence in the GABA motor neurons. Reference: Firnhaber C & Hammarlund M. PLoS Genet. 2013 Nov;9(11):e1003921."
Proper citation: RRID:WB-STRAIN:WBStrain00040650 Copy
http://www.wormbase.org/db/get?name=WBStrain00040656
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000089(aex-6)
Genomic Alteration: WBGene00000089(aex-6)
Availability: available
References:
Synonyms: aex-6(sa24) I; wpEx287.
Alternate IDs: WB-STRAIN:XE1890, CGC_XE1890
Notes: Made_by: Alexander Lin-Moore|"wpEx287 [unc-47p::aex-6::unc-54 3'UTR + myo-2p::mCherry]. Pick mCherry+ to maintain. aex-6 a.k.a. rab-27. Reference: Sekine Y, et al. Cell reports. 2018; 23(2):415-428."
Proper citation: RRID:WB-STRAIN:WBStrain00040656 Copy
http://www.wormbase.org/db/get?name=WBStrain00040655
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000089(aex-6)
Genomic Alteration: WBGene00000089(aex-6)
Availability: available
References:
Synonyms: aex-6(sa24) I; oxIs12 X.
Alternate IDs: WB-STRAIN:XE1873, CGC_XE1873
Notes: Made_by: Alexander Lin-Moore|"oxIs12 [unc-47p::GFP] X. GFP expression in GABA neurons. aex-6 a.k.a. rab-27. Reference: Sekine Y, et al. Cell reports. 2018; 23(2):415-428."
Proper citation: RRID:WB-STRAIN:WBStrain00040655 Copy
http://www.wormbase.org/db/get?name=WBStrain00040657
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: wpEx287.
Alternate IDs: WB-STRAIN:XE1892, CGC_XE1892
Notes: Made_by: Alexander Lin-Moore|"wpEx287 [unc-47p::aex-6::unc-54 3'UTR + myo-2p::mCherry]. Pick mCherry+ to maintain. aex-6 a.k.a. rab-27. Reference: Sekine Y, et al. Cell reports. 2018; 23(2):415-428."
Proper citation: RRID:WB-STRAIN:WBStrain00040657 Copy
http://www.wormbase.org/db/get?name=WBStrain00040653
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001332(eri-1)|WBGene00003004(lin-15)|WBGene00004323(rde-1)|WBGene00023497(lin-15B)
Genomic Alteration: WBGene00001332(eri-1), WBGene00003004(lin-15), WBGene00004323(rde-1), WBGene00023497(lin-15B)
Availability: available
References:
Synonyms: wpSi10 II; eri-1(mg366) IV; rde-1(ne219) V; lin-15B(n744) X.
Alternate IDs: WB-STRAIN:XE1581, CGC_XE1581
Notes: Made_by: C. Firnhaber|"wpSi10 [unc-17p::rde-1::SL2::sid-1 + Cbr-unc-119(+)] II. Maintain at 15-20C, sterile at 25C. Superficially wild-type. Cholinergic neuron-specific RNAi strain. Sensitivity to feeding RNAi is limited to the cholinergic neurons; all other tissues resistant. Reference: Firnhaber C & Hammarlund M. PLoS Genet. 2013 Nov;9(11):e1003921."
Proper citation: RRID:WB-STRAIN:WBStrain00040653 Copy
http://www.wormbase.org/db/get?name=WBStrain00040667
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000254(bli-4)|WBGene00001483(fog-3)|WBGene00006779(unc-43)
Genomic Alteration: WBGene00000254(bli-4), WBGene00001483(fog-3), WBGene00006779(unc-43)
Availability: available
References:
Synonyms: fog-3(q443) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); unc-43(n498) IV.
Alternate IDs: WB-STRAIN:XM1007, CGC_XM1007
Notes: Heterozygotes are Unc with pharyngeal GFP signal. Homozygous hT2[bli-4 let-? qIs48] are inviable. Homozygous unc-43(n498); fog-3(q443) animals are females.
Proper citation: RRID:WB-STRAIN:WBStrain00040667 Copy
http://www.wormbase.org/db/get?name=WBStrain00040700
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001851(hif-1)
Genomic Alteration: WBGene00001851(hif-1)
Availability: available
References:
Synonyms: hif-1(ia4) V; yakEx143.
Alternate IDs: WB-STRAIN:XZ2081, CGC_XZ2081
Notes: yakEx143 [dpy-7p::hif-1(cDNA) + myo-2p::mCherry]. Pick animals with red pharynx to maintain. HIF-1 expressed from a hypodermal-specific promoter in hif-1 mutant background for tissue-specific rescuing experiments. yakEx143 does not rescue lethality in hif-1 mutant animals exposed to 50ppm hydrogen sulfide. Reference: Topalidou I & and Miller DL. bioRxiv 174581; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00040700 Copy
http://www.wormbase.org/db/get?name=WBStrain00040669
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001482(fog-2)|WBGene00002144(inx-22)
Genomic Alteration: WBGene00001482(fog-2), WBGene00002144(inx-22)
Availability: available
References:
Synonyms: inx-22(tm1661) I; fog-2(q71) V.
Alternate IDs: WB-STRAIN:XM1012, CGC_XM1012
Notes: Mutagen:UV/TMP|"Negative regulator of oocyte maturation. Male/Female strain."
Proper citation: RRID:WB-STRAIN:WBStrain00040669 Copy
http://www.wormbase.org/db/get?name=WBStrain00040701
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001851(hif-1)
Genomic Alteration: WBGene00001851(hif-1)
Availability: available
References:
Synonyms: hif-1(ia4) V; yakEx144.
Alternate IDs: WB-STRAIN:XZ2082, CGC_XZ2082
Notes: yakEx144 [unc-14p::hif-1(cDNA) + myo-2p::mCherry]. Pick animals with red pharynx to maintain. HIF-1 expressed from unc-14 promoter in hif-1 mutant background for tissue-specific rescuing experiments. yakEx144 rescues lethality in hif-1 mutant animals exposed to 50ppm hydrogen sulfide. Reference: Topalidou I & and Miller DL. bioRxiv 174581; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00040701 Copy
http://www.wormbase.org/db/get?name=WBStrain00040663
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:XJ1
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040663 Copy
http://www.wormbase.org/db/get?name=WBStrain00040664
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00002689(let-479)|WBGene00006782(unc-46)
Genomic Alteration: WBGene00002689(let-479), WBGene00006782(unc-46)
Availability: available
References:
Synonyms: unc-46(e177) let-479(s1576) V/nT1 [qIs51] (IV;V).
Alternate IDs: WB-STRAIN:XK194, CGC_XK194
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040664 Copy
http://www.wormbase.org/db/get?name=WBStrain00040755
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00011333(nrde-2)
Genomic Alteration: WBGene00011333(nrde-2)
Availability: available
References:
Synonyms: nrde-2(gg95) II.
Alternate IDs: WB-STRAIN:YY156, CGC_YY156
Notes: Reference: Guang S, et al. Nature. 2010 Jun 24;465(7301):1097-101.
Proper citation: RRID:WB-STRAIN:WBStrain00040755 Copy
http://www.wormbase.org/db/get?name=WBStrain00040754
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004510(rrf-3)
Genomic Alteration: WBGene00004510(rrf-3)
Availability: available
References:
Synonyms: rrf-3(mg373) II; oxls12.
Alternate IDs: WB-STRAIN:YY13, CGC_YY13
Notes: oxls12 [unc-47p::GFP + lin-15(+)]. Enhanced RNAi. Sterile at 25 degrees. [NOTE: the genotype of YY13 as previously annotated only as rrf-3(mg373)] References: Pavelec DM, et al. Genetics. 2009 Dec;183(4):1283-95. PMID: 19797044. McIntire SL, et al. Nature. 1997 Oct 23;389(6653):870-6. PMID: 9349821.
Proper citation: RRID:WB-STRAIN:WBStrain00040754 Copy
http://www.wormbase.org/db/get?name=WBStrain00040757
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00007577(nrde-1)
Genomic Alteration: WBGene00007577(nrde-1)
Availability: available
References:
Synonyms: nrde-1(gg88) III.
Alternate IDs: WB-STRAIN:YY160, CGC_YY160
Notes: eri-1(mg366) has been crossed out of the background. Reference: Burkhart KB, et al. PLoS Genet. 2011 Aug;7(8):e1002249.
Proper citation: RRID:WB-STRAIN:WBStrain00040757 Copy
http://www.wormbase.org/db/get?name=WBStrain00040756
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00019862(nrde-3)
Genomic Alteration: WBGene00019862(nrde-3)
Availability: available
References:
Synonyms: nrde-3(gg66) X.
Alternate IDs: WB-STRAIN:YY158, CGC_YY158
Notes: Nuclear RNAi defective. Reference: Guang et al., Science 321(5888):537-41 (2009).
Proper citation: RRID:WB-STRAIN:WBStrain00040756 Copy
http://www.wormbase.org/db/get?name=WBStrain00040751
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000793(crh-1)
Genomic Alteration: WBGene00000793(crh-1)
Availability: available
References:
Synonyms: crh-1(tz2) III.
Alternate IDs: WB-STRAIN:YT17, CGC_YT17
Notes: Clumpy, pale and slightly small, tend to dig into plate. Daf-c at 27C. Do not distribute this strain; other labs should request it from the CGC.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00040751 Copy
http://www.wormbase.org/db/get?name=WBStrain00040753
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000939(dcr-1)
Genomic Alteration: WBGene00000939(dcr-1)
Availability: available
References:
Synonyms: dcr-1(mg375) III
Alternate IDs: WB-STRAIN:YY11, CGC_YY11
Notes: Enhanced RNAi. Sterile at 25 degrees. Referenced in Pavelec et al. Genetics (2009).
Proper citation: RRID:WB-STRAIN:WBStrain00040753 Copy
http://www.wormbase.org/db/get?name=WBStrain00040752
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000426(ced-12)
Genomic Alteration: WBGene00000426(ced-12)
Availability: available
References:
Synonyms: ced-12(tp2) I.
Alternate IDs: WB-STRAIN:YW16, CGC_YW16
Notes: Persisting cell corpses. Distal tip cell migration defective.
Proper citation: RRID:WB-STRAIN:WBStrain00040752 Copy
http://www.wormbase.org/db/get?name=WBStrain00040769
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003992(pgl-1)|WBGene00014208(znfx-1)
Genomic Alteration: WBGene00003992(pgl-1), WBGene00014208(znfx-1)
Availability: available
References:
Synonyms: znfx-1(gg544[3xflag::gfp::znfx-1]) II; pgl-1(gg547[pgl-1::3xflag::tagRFP]) IV.
Alternate IDs: WB-STRAIN:YY968, CGC_YY968
Notes: 3xflag::gfp inserted into endogenous znfx-1 locus, and 3xflag::tagRFP inserted into endogenous pgl-1 locus using CRISPR/Cas9 engineering. Reference: Wan G, et al. Nature. 2018 May;557(7707):679-683.
Proper citation: RRID:WB-STRAIN:WBStrain00040769 Copy
http://www.wormbase.org/db/get?name=WBStrain00040760
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00019971(ergo-1)
Genomic Alteration: WBGene00019971(ergo-1)
Availability: available
References:
Synonyms: ergo-1(gg102) V.
Alternate IDs: WB-STRAIN:YY169, CGC_YY169
Notes: Enhanced RNAi. Isolated in lin-15B RNAi screen. Referenced in Pavelec et al. Genetics (2009).
Proper citation: RRID:WB-STRAIN:WBStrain00040760 Copy
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