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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040308
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00013164(Y53F4B.18)
Genomic Alteration: WBGene00013164(Y53F4B.18)
Availability: available
References:
Synonyms: Y53F4B.18(vq3) II.
Alternate IDs: WB-STRAIN:VV213, CGC_VV213
Notes: Made_by: Alan To|"Superficially wild-type. Reference: Chen AL, et al. Nat Chem Biol. 2019 Mar 25. doi: 10.1038/s41589-019-0243-4."
Proper citation: RRID:WB-STRAIN:WBStrain00040308 Copy
http://www.wormbase.org/db/get?name=WBStrain00040309
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00015062(trx-1)
Genomic Alteration: WBGene00015062(trx-1)
Availability: available
References:
Synonyms: trx-1(ok1449) II.
Alternate IDs: WB-STRAIN:VZ1, CGC_VZ1
Notes: B0228.5 Homozygous. Exhibits slightly shortened lifespan compared to wild-type. Outer Left Sequence: cgccgtggttaacctcttta. Outer Right Sequence: ttatcggacaataggcggac. Inner Left Sequence: ctgttgactcccaacaccct. Inner Right Sequence: ttgcaaaagaaattttcgcc. Inner Primer PCR Length: 2357. Estimated Deletion Size: about 850 bp. This strain was provided by the C. elegans Gene Knockout Project at OMRF, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. URL: www.mutantfactory.ouhsc.edu/ Reference: Miranda-Vizuete A, et al. FEBS Lett. 2006 Jan 23;580(2):484-90.|"Made_by: A. Miranda Vizuete"|"Supplementary_genotype trx-1(ok1449)"
Proper citation: RRID:WB-STRAIN:WBStrain00040309 Copy
http://www.wormbase.org/db/get?name=WBStrain00040383
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)|WBGene00016395(spcs-1)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119), WBGene00016395(spcs-1)
Availability: available
References:
Synonyms: unc-119(ed3) III; ojIs23.
Alternate IDs: WB-STRAIN:WH327, CGC_WH327
Notes: ojIs23 [pie-1p::GFP::C34B2.10].|"Reference WBPaper00055815 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype unc-119(ed3) III; ojIs23 [Ppie-1GFP::SP12]"
Proper citation: RRID:WB-STRAIN:WBStrain00040383 Copy
http://www.wormbase.org/db/get?name=WBStrain00040386
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004274(rab-11.1)
Genomic Alteration: WBGene00004274(rab-11.1)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:WH0347
Notes: Retired following removal of zero padded strain public_names.
Proper citation: RRID:WB-STRAIN:WBStrain00040386 Copy
http://www.wormbase.org/db/get?name=WBStrain00040380
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ojIs12.
Alternate IDs: WB-STRAIN:WH279, CGC_WH279
Notes: ojIs12 [cyk-4::GFP + unc-119(+)]. Strain is not very healthy. Described as integratred array but appears to segregate Uncs. Maintain at 15-20C.
Proper citation: RRID:WB-STRAIN:WBStrain00040380 Copy
http://www.wormbase.org/db/get?name=WBStrain00040304
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00045328(mir-794)|WBGene00045329(mir-795)
Genomic Alteration: WBGene00045328(mir-794), WBGene00045329(mir-795)
Availability: available
References:
Synonyms: mir-794 mir-795(maDf5) I.
Alternate IDs: WB-STRAIN:VT3301, CGC_VT3301
Notes: mir-794 mir-795(maDf5) enhances retarded phenotypes of mir-48 mir-241 (nDF51). maDf5 allele is missing the 1312 nucleotide region between ATACATATTCCGAGAAACGTTACCT and GTGAGGCGCCAAATGCCGGCCTCAC [chrI:12,594,556-12,595,917 of WBcel235/ce11].
Proper citation: RRID:WB-STRAIN:WBStrain00040304 Copy
http://www.wormbase.org/db/get?name=WBStrain00040303
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00045329(mir-795)
Genomic Alteration: WBGene00045329(mir-795)
Availability: available
References:
Synonyms: mir-795(ma298) I; maIs105 V.
Alternate IDs: WB-STRAIN:VT3299, CGC_VT3299
Notes: maIs105 [col-19::GFP] V. mir-795(ma298) enhances retarded phenotypes of mir-48 mir-241 (nDF51). ma298 allele is missing the 5 nucleotides between CCGAGAAACGTTACCTGCT and AGATTGATCAGCGAGCTTGA [chrI:12,594,565-12,594,608 of WBcel235/ce11].
Proper citation: RRID:WB-STRAIN:WBStrain00040303 Copy
http://www.wormbase.org/db/get?name=WBStrain00040306
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004780(ser-7)
Genomic Alteration: WBGene00004780(ser-7)
Availability: available
References:
Synonyms: ser-7(vq2) X.
Alternate IDs: WB-STRAIN:VV207, CGC_VV207
Notes: CRISPR/Cas9-engineered knockout of ser-7. Resistant to exogenous serotonin induced food intake. Reference: Perez-Gomez A., et al. Nat Commun. 2018 Dec 10;9(1):5272.|"Made_by: Alan To"
Proper citation: RRID:WB-STRAIN:WBStrain00040306 Copy
http://www.wormbase.org/db/get?name=WBStrain00040305
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001072(dpy-10)|WBGene00001842(her-1)|WBGene00003598(nhl-2)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001842(her-1), WBGene00003598(nhl-2)
Availability: unknown
References:
Synonyms: nDf50/mIn1 [mIs14 dpy-10(e128)] II; nhl-2(ok818) III; her-1(n695) V.
Alternate IDs: WB-STRAIN:VT3363
Notes: Pick wild-type GFP+ to maintain. Heterozygotes are WT with GFP+ pharynx, and segregate Dpy GFP+ mIn1 homozygotes, and GFP- low viability non-Egl hermaphrodites. Viability of first generation nDf50 homozygotes (GFP-) segregated from balanced heterozygotes is rescued by maternal contribution of mir-35-41 from balancer. Second generation GFP- animals are low viability. Reference: McJunkin K, Ambros V. Genes Dev. 2017 Feb 15;31(4):422-437.
Proper citation: RRID:WB-STRAIN:WBStrain00040305 Copy
http://www.wormbase.org/db/get?name=WBStrain00040388
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004027(pie-1)
Genomic Alteration: WBGene00004027(pie-1)
Availability: unknown
References:
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:WH0351
Notes: Retired following removal of zero padded strain public_names.
Proper citation: RRID:WB-STRAIN:WBStrain00040388 Copy
http://www.wormbase.org/db/get?name=WBStrain00040387
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004274(rab-11.1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004274(rab-11.1), WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ojIs35.
Alternate IDs: WB-STRAIN:WH347, CGC_WH347
Notes: Made_by: Jane Squirrell|"ojIs35 [pie-1::GFP::rab-11.1 + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00040387 Copy
http://www.wormbase.org/db/get?name=WBStrain00040389
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ojIs37.
Alternate IDs: WB-STRAIN:WH351, CGC_WH351
Notes: Made_by: Jane Squirrell|"ojIs37 [pie-1p::GFP::ugtp-1 + unc-119(+)]. Maintain under normal conditions. Reference: Bembenek J, et al. Development. (2007) 134(21):3837-48."
Proper citation: RRID:WB-STRAIN:WBStrain00040389 Copy
http://www.wormbase.org/db/get?name=WBStrain00040472
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000232(avr-14)|WBGene00000233(avr-15)|WBGene00000254(bli-4)|WBGene00001591(glc-1)|WBGene00008400(drh-3)
Genomic Alteration: WBGene00000232(avr-14), WBGene00000233(avr-15), WBGene00000254(bli-4), WBGene00001591(glc-1), WBGene00008400(drh-3)
Availability: available
References:
Synonyms: avr-14(ad1302) drh-3(tm1217) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); avr-15(ad1051) glc-1(pk54)) V.
Alternate IDs: WB-STRAIN:WM216, CGC_WM216
Notes: Heterozygotes are wild-type, GFP+ and sensitive to ivermectin. Segregates non-GFP drh-3 homozygotes (sterile, resisitant to ivermectin), arrested hT2 aneuploids, and wild-type GFP+ heterozygotes. Maintain by picking GFP+. Do not distribute this strain; other labs should request it directly from the CGC. Reference: Claycomb JM, et al. Cell. 2009 Oct 2;139(1):123-34.
Proper citation: RRID:WB-STRAIN:WBStrain00040472 Copy
http://www.wormbase.org/db/get?name=WBStrain00040473
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00008400(drh-3)
Genomic Alteration: WBGene00008400(drh-3)
Availability: available
References:
Synonyms: drh-3(ne3197) I.
Alternate IDs: WB-STRAIN:WM230, CGC_WM230
Notes: Mutator. Dominant RNAi-deficient. Temperature-sensitive sterile. Maintain at 15-20C. ne3197 is a G840D missense mutation. Reference: Gu W, et al. Mol Cell. 2009 Oct 23;36(2):231-44.
Proper citation: RRID:WB-STRAIN:WBStrain00040473 Copy
http://www.wormbase.org/db/get?name=WBStrain00040476
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004178(prg-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004178(prg-1), WBGene00006843(unc-119)
Availability: available
References:
Synonyms: prg-1(tm872) I; neSi14 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:WM274, CGC_WM274
Notes: neSi14 [FLAG::prg-1 + Cbr-unc-119(+)] II. MosSCI insertion into ttTi5605 (LG II). Reference: Lee HC, et al. Cell. 2012 Jul 6;150(1):78-87.
Proper citation: RRID:WB-STRAIN:WBStrain00040476 Copy
http://www.wormbase.org/db/get?name=WBStrain00040478
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: rde-3(ne3370) I.
Alternate IDs: WB-STRAIN:WM286, CGC_WM286
Notes: Made_by: Gisela Chen|"RNAi deficient. Temperature-sensitive sterile. In-frame deletion. Reference: Chen CC, et al. Curr Biol. 2005 Feb 22;15(4):378-83."
Proper citation: RRID:WB-STRAIN:WBStrain00040478 Copy
http://www.wormbase.org/db/get?name=WBStrain00040407
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001063(dpy-1)|WBGene00015267(chin-1)
Genomic Alteration: WBGene00001063(dpy-1), WBGene00015267(chin-1)
Availability: available
References:
Synonyms: chin-1(tm1909)/sC1 [dpy-1(s2170) let(gk597)] III; ddIs?.
Alternate IDs: WB-STRAIN:WH532, CGC_WH532
Notes: ddIs? [pie-1p::GFP::par-6 + unc-119(+)]. Maintain under normal conditions. Heterozygotes are WT, and segregate WT, occasional Dpy (non-let recombinant sC1 homozygotes), and nearly sterile tm1909 homozygotes. Pick WT and check for correct segregation of progeny to maintain. Reference: Kumfer et al. (2010) Mol Bio Cell21(2):266-77.
Proper citation: RRID:WB-STRAIN:WBStrain00040407 Copy
http://www.wormbase.org/db/get?name=WBStrain00040406
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006496(cgef-1)
Genomic Alteration: WBGene00006496(cgef-1)
Availability: available
References:
Synonyms: cgef-1(gk261) X; itIs153.
Alternate IDs: WB-STRAIN:WH530, CGC_WH530
Notes: itIs153 [pie-1p::par-2::GFP + rol-6(su1006) + N2 genomic DNA]. Maintain at 24 degrees; sick at 25 C, GFP lost at 20C. itIs153 is an integrated derivitive of axEx1094. Reference: Kumfer et al. (2010) Mol Bio Cell21(2):266-77.
Proper citation: RRID:WB-STRAIN:WBStrain00040406 Copy
http://www.wormbase.org/db/get?name=WBStrain00040408
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001063(dpy-1)|WBGene00015267(chin-1)
Genomic Alteration: WBGene00001063(dpy-1), WBGene00015267(chin-1)
Availability: available
References:
Synonyms: chin-1(tm1909)/sC1 [dpy-1(s2170) let(gk597)] III; ddIs?.
Alternate IDs: WB-STRAIN:WH533, CGC_WH533
Notes: ddIs? [pie-1p::mCherry::par-6 + unc-119(+)]. Maintain under normal conditions. Heterozygotes are WT, and segregate WT, occasional Dpy (non-let recombinant sC1 homozygotes), and nearly sterile tm1909 homozygotes. Pick WT and check for correct segregation of progeny to maintain. Reference: Kumfer et al. (2010) Mol Bio Cell21(2):266-77.
Proper citation: RRID:WB-STRAIN:WBStrain00040408 Copy
http://www.wormbase.org/db/get?name=WBStrain00040483
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: Caenorhabditis elegans wild isolate.
Alternate IDs: WB-STRAIN:WN2010
Notes: Isotype: WN2001|"Reference_strain: False"|"Sequenced: True"
Proper citation: RRID:WB-STRAIN:WBStrain00040483 Copy
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