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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040343
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: wbmIs76 IV.
Alternate IDs: WB-STRAIN:WBM1179, CGC_WBM1179
Notes: Made_by: Carlos G Silva-Garca and Caroline Heintz|"wbmIs76 [eft-3p::3XFLAG::dpy-10 crRNA::unc-54 3'UTR] (IV:5015000). Superficially wild-type. SKI LODGE system allows for CRISPR knock-in of single-copy transcripts downstream of a tissue-specific promoter. wbmIs76 can be used to direct soma-specific gene expression from the eft-3 promoter through CRISPR-mediated insertion of transcripts downstream of tissue-specific eft-3 promoter inserted as a single copy into the C. elegans genome. Reference: Silva-Garca CG, et al. G3 (Bethesda). 2019 Jul 9;9(7):2195-2198."|"wbmIs76 [eft-3p::3XFLAG::dpy-10 crRNA::unc-54 3'UTR] (IV:5015000). Superficially wild-type. wbmIs76 can be used to direct soma-specific gene expression from the eft-3 promoter through CRISPR-mediated insertion of transcripts downstream of tissue-specific eft-3 promoter inserted as a single copy into the C. elegans genome. Reference: Silva-Garca CG, et al. Single-copy Knock-In Loci for Defined Gene Expression in C. elegans. BioRxiv. December 19, 2018 doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00040343 Copy
http://www.wormbase.org/db/get?name=WBStrain00040319
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: vzEx8.
Alternate IDs: WB-STRAIN:VZ55, CGC_VZ55
Notes: vzEx8 [trx-2p(4 kb)::trx-2::GFP + rol-6(su1006)]. Rollers. Pick rollers to maintain. Reference: Cacho-Valdez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400.
Proper citation: RRID:WB-STRAIN:WBStrain00040319 Copy
http://www.wormbase.org/db/get?name=WBStrain00040318
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00022663(glrx-21)
Genomic Alteration: WBGene00022663(glrx-21)
Availability: available
References:
Synonyms: glrx-21(tm2921) III.
Alternate IDs: WB-STRAIN:VZ54, CGC_VZ54
Notes: Made_by: F. Munoz Lobato|"Superficially wild-type. Hypersensitive to selenium-induced motility impairment, but not lethality. Reference: Morgan KL, et al., Toxicol Sci. 2010 Dec;118(2):530-43."
Proper citation: RRID:WB-STRAIN:WBStrain00040318 Copy
http://www.wormbase.org/db/get?name=WBStrain00040394
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) ojIs58 III.
Alternate IDs: WB-STRAIN:WH416, CGC_WH416
Notes: ojIs58 [pie-1p::sep-1::GFP + unc-119(+)] III. Maintain under normal conditions. Reference: Bembenek J, et al. Development. (2007) 134(21):3837-48.
Proper citation: RRID:WB-STRAIN:WBStrain00040394 Copy
http://www.wormbase.org/db/get?name=WBStrain00040397
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000254(bli-4)|WBGene00004775(sep-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00004775(sep-1)
Availability: available
References:
Synonyms: sep-1(e2406) I/hT2 (I;III); ojIs58 III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WH485, CGC_WH485
Notes: ojIs58 [pie-1p::sep-1::GFP + unc-119(+)] III. Homozygous embryonic lethal mutation balanced by bli-4- and GFP-marked translocation. Maintain at 15 C. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP e2406 homozygotes (embryonic arrest). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Bembenek J, et al. Curr Biol (2010) Feb 9;20(3):259-64.
Proper citation: RRID:WB-STRAIN:WBStrain00040397 Copy
http://www.wormbase.org/db/get?name=WBStrain00040396
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000254(bli-4)|WBGene00004775(sep-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00004775(sep-1)
Availability: available
References:
Synonyms: sep-1(e2406) I/hT2 (I;III); ruIs32 III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WH468, CGC_WH468
Notes: ruIs32 [pie-1p::GFP::H2B + unc-119(+)] III. Homozygous embryonic lethal mutation balanced by bli-4- and GFP-marked translocation. Maintain at 15 C. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP e2406 homozygotes (embryonic arrest). Homozygous hT2 [bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Bembenek J, et al. Curr Biol (2010) Feb 9;20(3):259-64.
Proper citation: RRID:WB-STRAIN:WBStrain00040396 Copy
http://www.wormbase.org/db/get?name=WBStrain00040392
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000254(bli-4)|WBGene00004775(sep-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00004775(sep-1)
Availability: available
References:
Synonyms: sep-1(e2406) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WH408, CGC_WH408
Notes: Homozygous embryonic lethal mutation balanced by bli-4- and GFP-marked translocation. Maintain at 15 C. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP e2406 homozygotes (embryonic arrest). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Bembenek J, et al. Curr Biol (2010) Feb 9;20(3):259-64.
Proper citation: RRID:WB-STRAIN:WBStrain00040392 Copy
http://www.wormbase.org/db/get?name=WBStrain00040314
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00007099(trx-2)|WBGene00014028(trxr-2)
Genomic Alteration: WBGene00007099(trx-2), WBGene00014028(trxr-2)
Availability: available
References:
Synonyms: trxr-2(tm2047) III; trx-2(tm2720) V.
Alternate IDs: WB-STRAIN:VZ17, CGC_VZ17
Notes: Made_by: Briseida Cacho|"Superficially wild-type. Reference: Cacho-Valdez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400."
Proper citation: RRID:WB-STRAIN:WBStrain00040314 Copy
http://www.wormbase.org/db/get?name=WBStrain00040311
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00007099(trx-2)
Genomic Alteration: WBGene00007099(trx-2)
Availability: available
References:
Synonyms: trx-2(tm2720) V.
Alternate IDs: WB-STRAIN:VZ13, CGC_VZ13
Notes: Made_by: Briseida Cacho|"Superficially wild-type. Reference: Cacho-Valdez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400."
Proper citation: RRID:WB-STRAIN:WBStrain00040311 Copy
http://www.wormbase.org/db/get?name=WBStrain00040398
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ojIs69.
Alternate IDs: WB-STRAIN:WH497, CGC_WH497
Notes: ojIs69 [pie-1::mGFP::chin-1 + unc-119(+)]. N-terminal fusion of mGFP to sole predicted BE0003N10.2 ORF. Reference: Kumfer et al. (2010) Mol Biol Cell (2):266-77.
Proper citation: RRID:WB-STRAIN:WBStrain00040398 Copy
http://www.wormbase.org/db/get?name=WBStrain00040313
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00014028(trxr-2)
Genomic Alteration: WBGene00014028(trxr-2)
Availability: available
References:
Synonyms: trxr-2(ok2267) III.
Alternate IDs: WB-STRAIN:VZ15, CGC_VZ15
Notes: Made_by: Briseida Cacho|"Superficially wild-type. ok2267 removes bases +114 to 1751 relative to the start of the trxr-2 coding sequence. Reference: Cacho-Valdez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400."
Proper citation: RRID:WB-STRAIN:WBStrain00040313 Copy
http://www.wormbase.org/db/get?name=WBStrain00040312
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00014028(trxr-2)|WBGene00015553(trxr-1)
Genomic Alteration: WBGene00014028(trxr-2), WBGene00015553(trxr-1)
Availability: available
References:
Synonyms: trxr-2(tm2047) III; trxr-1(sv47) IV.
Alternate IDs: WB-STRAIN:VZ14, CGC_VZ14
Notes: Made_by: B. Cacho Valadez|"sv47 deletion removes bases 721-2383 of the trxr-1 genomic sequence (as measured from the start of the trxr-1 coding sequence). tm2047 removes bases -128 to +380 relative to the start of the trxr-2 coding sequence (removing part of the proximal promoter). tm2047 outcrossed 6x. sv47 outcrossed 10x. Reference: Cacho-Valadez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400."
Proper citation: RRID:WB-STRAIN:WBStrain00040312 Copy
http://www.wormbase.org/db/get?name=WBStrain00040325
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: vzEx60.
Alternate IDs: WB-STRAIN:VZ184, CGC_VZ184
Notes: Made_by: F Muoz Lobato|"vzEx60 [dnj-27p(2kb)::dnj-27::YFP::KDEL]. Superficially wild-type. Pick YFP+ to maintain. Fluorescence should be easily detected under a dissection scope if present, but array has low transmission rate. Reference: Muoz-Lobato F, et al. Antioxid Redox Signal. 2014 Jan 10; 20(2): 217-235."|"vzEx60 [dnj-27p(2kb)::dnj-27::YFP::KDEL]. Superficially wild-type. Pick YFP+ to maintain. Reference: Muoz-Lobato F, et al. Antioxid Redox Signal. 2014 Jan 10; 20(2): 217-235."
Proper citation: RRID:WB-STRAIN:WBStrain00040325 Copy
http://www.wormbase.org/db/get?name=WBStrain00040328
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001078(dpy-19)|WBGene00001609(glp-1)|WBGene00008117(gsr-1)
Genomic Alteration: WBGene00001078(dpy-19), WBGene00001609(glp-1), WBGene00008117(gsr-1)
Availability: available
References:
Synonyms: gsr-1(tm3574)/qC1 dpy-19(e1259) glp-1(q339) nIs281 III.
Alternate IDs: WB-STRAIN:VZ454, CGC_VZ454
Notes: Made_by: Francisco Jos Naranjo-Galindo|"nIs281 [myo-2::RFP] integrated near qC1. Recombination between nIs281 and qC1 has been reported. Fails to complemement all markers on qC1. Heterozygotes are WT and segregate WT, Dpy Sterile, and tm3574 homozygotes. gsr-1(tm3574) is embryonic lethal. gsr-1(m+,z-) animals are viable and reach adulthood with no visible phenotype and lay eggs that invariably arrest at the pregastrula stage; they are slightly short-lived, have increased mitochondrial fragmentation, decreased mitochondrial DNA content and have induced mitochondrial UPR measured by hsp-6::GFP levels. gsr-1(m-,z-) have aberrant perinuclear distribution of interphasic chromatin. NOTE: The RFP-labeled balancer is reportedly not entirely stable in this strain and will occasionally segregate recombinants of two types: sterile RFP+ animals (most likely homozygous qC1 [nIs281] worms that are able to grow to adulthood but do not develop germline), and non-RFP animals that lay viable progeny. Maintain by picking fertile RFP+ animals and confirming that non-RFP progeny lay 100% arrested embryos. Reference: Mora-Lorca JA, et al. Free Radic Biol Med. 2016 Jul;96:446-61."
Proper citation: RRID:WB-STRAIN:WBStrain00040328 Copy
http://www.wormbase.org/db/get?name=WBStrain00040322
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: vzEx32.
Alternate IDs: WB-STRAIN:VZ119, CGC_VZ119
Notes: vzEx32 [(pVZ35) trx-3p::GFP + (pRF4) rol-6(su1006)]. Rollers. Pick Rollers to maintain. GFP expression in intestine. Reference: Jimnez-Hidalgo M, et al. Free Radic Biol Med. (2014) 68:205-219.|"vzEx32 [trx-3p::GFP + rol-6(su1006)]. Rollers. Pick Rollers to maintain. GFP expression in intestine. Reference: Jimnez-Hidalgo M, et al. Free Radic Biol Med. (2014) 68:205-219."
Proper citation: RRID:WB-STRAIN:WBStrain00040322 Copy
http://www.wormbase.org/db/get?name=WBStrain00040324
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: vzEx41.
Alternate IDs: WB-STRAIN:VZ149, CGC_VZ149
Notes: Made_by: F Muoz Lobato|"vzEx41 [dnj-27p(2kb)::dnj-27::dnj-27 3'UTR + unc-122p::GFP]. Superficially wild-type. Pick GFP+ to maintain. Reference: Muoz-Lobato F, et al. Antioxid Redox Signal. 2014 Jan 10; 20(2): 217-235."
Proper citation: RRID:WB-STRAIN:WBStrain00040324 Copy
http://www.wormbase.org/db/get?name=WBStrain00040372
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00000254(bli-4)|WBGene00004775(sep-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00004775(sep-1)
Availability: available
References:
Synonyms: sep-1(e2406) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WH216, CGC_WH216
Notes: Heterozygotes have myo-2::GFP [qIs48] strongly expressed in the pharynx and are viable at 25C. 100% of sep-1 homozygotes are strongly Sterile Unc at 25C (at 20C, 100% are Sterile but no so Unc). Up to 30% of the homozygotes are Sterile at 16C. hT2[qIs48] homozygotes are dead. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype.|"Reference WBPaper00059538 added based on published strain data identified by Textpresso literature search."
Proper citation: RRID:WB-STRAIN:WBStrain00040372 Copy
http://www.wormbase.org/db/get?name=WBStrain00040370
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006795(unc-61)
Genomic Alteration: WBGene00006795(unc-61)
Availability: available
References:
Synonyms: unc-61(n3169) V.
Alternate IDs: WB-STRAIN:WH202, CGC_WH202
Notes: Poor backward movement. Protrusive vulva. Gonad extrusion. Egg-laying defects. Recessive.
Proper citation: RRID:WB-STRAIN:WBStrain00040370 Copy
http://www.wormbase.org/db/get?name=WBStrain00040377
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001018(dnc-2)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00001018(dnc-2), WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ojIs57.
Alternate IDs: WB-STRAIN:WH258, CGC_WH258
Notes: ojIs57 [pie-1::GFP::dnc-2 + unc-119(+)]|"Supplementary_genotype unc-119(ed3) III; ojIs5"
Proper citation: RRID:WB-STRAIN:WBStrain00040377 Copy
http://www.wormbase.org/db/get?name=WBStrain00040378
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)|WBGene00013168(arp-1)
Genomic Alteration: WBGene00006843(unc-119), WBGene00013168(arp-1)
Availability: available
References:
Synonyms: unc-119(ed3) III; ojIs47.
Alternate IDs: WB-STRAIN:WH259, CGC_WH259
Notes: ojIs47 [arp-1::GFP + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00040378 Copy
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