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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156403001
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Live Animals; Cryopreserved Embryo (as of 2024-08-06)
References:
Synonyms:
Alternate IDs: 156403001
Notes: These are re-derived rats of from BUF/Mna and maintained at Medical College of Wisconsin. BUF strain originated from Heston 1946 from Buffalo stock of H. Morris. To NIH in 1950 at F10. RGD HRDP, contact Hybrid Rat Diversity Program at
[email protected]
Proper citation: RRID:RGD_156403001 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430328
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 156430328
Notes: Flinders Resistant Line Rat (FRL) was selectively bred from outbred Sprague Dawley for less response to an anticholinesterase agent than FSL. FRL is not more resistant to the anticholinesterase agent compared to other outbred rats. The FSL rat
partially resembles depressed individuals with phenotypes of reduced appetite and psychomotor function but exhibits normal hedonic
responses and cognitive function.
Proper citation: RRID:RGD_156430328 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430327
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 156430327
Notes: Flinders Sensitive Line Rat (FSL) was selectively bred from outbred Sprague Dawley for increased response an anticholinesterase agent. The FSL rat
partially resembles depressed individuals with phenotypes of reduced appetite and psychomotor function but exhibits normal hedonic
responses and cognitive function.
Proper citation: RRID:RGD_156430327 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=401901199
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 401901199
Notes: The lean SHHFcp/+ is heterozygous for the corpulent allele and is the control model for the obese SHHFcp/cp. The Breeding stock for this colony was transferred to Dr. Sylvia McCune at the University of Chicago Medical School in 1983 from the laboratory of J.E. Miller at G.D. Searle and Company. The animals were developed by backcrossing the SHROB rat to the SHR/N rat. Dr. McCune obtained the colony after the seventh backcross and continued to inbreed past 20 generations to fix the congestive heart failure trait. To Genetic Models, Inc. in 1994. To Charles River in 2001. Charles River Laboratories
Proper citation: RRID:RGD_401901199 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=401901198
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 401901198
Notes: The obese SHHFcp/cp are homozygous for the corpulent allele. The Breeding stock for this colony was transferred to Dr. Sylvia McCune at the University of Chicago Medical School in 1983 from the laboratory of J.E. Miller at G.D. Searle and Company. The animals were developed by backcrossing the SHROB rat to the SHR/N rat. Dr. McCune obtained the colony after the seventh backcross and continued to inbreed past 20 generations to fix the congestive heart failure trait. To Genetic Models, Inc. in 1994. To Charles River in 2001. Charles River Laboratories
Proper citation: RRID:RGD_401901198 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878049
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 405878049
Notes: This the hypotensive strain established from the selective breeding In 1969. Outbred Sprague-Dawley rats were selected for systolic blood pressure trait using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LN was maintained as a normotensive control, and LH as a hypertensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews). This LL is the parent to LL substrains maintained in other institutions.
Proper citation: RRID:RGD_405878049 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878048
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 405878048
Notes: In 1969 outbred Sprague-Dawley rats were selected for high systolic blood pressure using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LN was maintained as a normotensive control, and LL as a hypotensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews). This LH is the parent to LH substrains maintained in other institutions.
Proper citation: RRID:RGD_405878048 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878050
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 405878050
Notes: This is the normotensive control strain established from the selective breeding In 1969. Outbred Sprague-Dawley rats were selected for systolic blood pressure trait using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LH was maintained as a hypertensive strain, and LL as a hypotensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews). This LN is the parent to LN substrains maintained in other institutions.
Proper citation: RRID:RGD_405878050 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878052
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 405878052
Notes: Originally developed before 1965 by Sidman from stock obtained from Sorsby of the Royal College of Surgeons, This RCS is the parent to RCS substrains maintained in other institutions.The RCS/LavRrrc substrain is available from Rat Resource & Research Center.
Proper citation: RRID:RGD_405878052 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878051
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown (as of 2024-07-09)
References:
Synonyms:
Alternate IDs: 405878051
Notes: This strain has been selected for high open-field defecation (a test of emotional reactivity). The underlying genetic basis for this phenotype is not known. Originally selected by Broadhurst in 1954 for high open-field defacation (OFD) response in an open field. This MR is the parent to MR substrains maintained in other institutions.
Proper citation: RRID:RGD_405878051 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=407450403
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 407450403
Notes: Substrain of BN maintained at Shanghai laboratory animal center of the Chinese Academy of Sciences, Shanghai, China Shanghai laboratory animal center of the Chinese Academy of Sciences, Shanghai, China
Proper citation: RRID:RGD_407450403 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155260360
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Live Animals; Cryopreserved Embryo (as of 2023-10-25)
References:
Synonyms:
Alternate IDs: RGD_155260360, 155260360, RRRC_966, RRRC_0966, RRRC_00966
Notes: Donated from Michael Gould/Jim Shull at University of Wisconsin Madison to Rat Resource & Research Center, Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: RRID:RRRC_00966 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1566455
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery
References:
Synonyms:
Alternate IDs: RGD_1566455, 1566455, RRRC_50, RRRC_050, RRRC_0050, RRRC_00050
Notes: Available at RRRC;these were originally bred by D. F. Kohn, Inst. of Comparative Medicine,Columbia University, New York. Then housed at University of Florida 1992 at F30. Rat Resource and Research Center
Proper citation: RRID:RRRC_00050 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10024
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo
References:
Synonyms:
Alternate IDs: RGD_10024, 10024, RRRC_168, RRRC_0168, RRRC_00168
Notes: To N 1951 from Heston at F51. Developed by Curtis at Columbia University Institute for Cancer Research, 1920; to Heston, 1949 at F49. Rat Resource and Research Center
Proper citation: RRID:RRRC_00168 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578699
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery
References:
Synonyms:
Alternate IDs: RGD_1578699, 1578699, RRRC_72, RRRC_072, RRRC_0072, RRRC_00072
Notes: These are descendants of the original Belgrade colony which was obtained by K. Kellar Centers forDisease Control and Prevention, Atlanta, GA. These were backcrossed with Harlan Sprague-Dawley Wistar and then amintained as a closed colony in Buffalo, NY. Rat Resource and Research Center
Proper citation: RRID:RRRC_00072 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578703
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Alternate IDs: RGD_1578703, 1578703, RRRC_69, RRRC_069, RRRC_0069, RRRC_00069
Notes: Selective breeding of Long-Evans in active two-way shuttle box for low avoidance resulted in these SLA rats. Rat Resource and Research Center
Proper citation: RRID:RRRC_00069 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=68077
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Alternate IDs: RGD_68077, 68077, RRRC_59, RRRC_059, RRRC_0059, RRRC_00059
Notes: Lyon Low-Tensive. See LH Rat Resource and Research Center
Proper citation: RRID:RRRC_00059 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=61015
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Alternate IDs: RGD_61015, 61015, RRRC_58, RRRC_058, RRRC_0058, RRRC_00058
Notes: (taken from Lyon Hypertensive entry, see LH) In 1969 outbred Sprague-Dawley rats were selected for high systolic blood pressure using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LN was maintained as a normotensive control, and LL as a hypotensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews). Rat Resource and Research Center
Proper citation: RRID:RRRC_00058 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10041
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Alternate IDs: RGD_10041, 10041, RRRC_55, RRRC_055, RRRC_0055, RRRC_00055
Notes: Strain originated from a colony of Sprague-Dawley outbred rats developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for sensitivity to salt-induced hypertension (Dahl et al 1962a,b, Rapp 1982) Rat Resource and Research Center
Proper citation: RRID:RRRC_00055 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9999141
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: RGD_9999141, 9999141, RRRC_732, RRRC_0732, RRRC_00732
Notes: The IRL/NCr rat strain was received into the NIH Genetic Resources program in 1987, now maintained at NCI Animal production program Rat Resource and Research Center
Proper citation: RRID:RRRC_00732 Copy
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