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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054296
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-22)
References:
Synonyms:
Alternate IDs: 10054296
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Arhgef11 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp deletion in the Arhgef11 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054296 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054453
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: 10054453
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Sirt3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 7-bp deletion in the Sirt3 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054453 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054456
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-22)
References:
Synonyms:
Alternate IDs: 10054456
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Sirt3 gene of T2DN/Mcwi rat embryos. The resulting mutation is a 82-bp deletion of exon 3 in the Sirt3 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054456 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054450
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-22)
References:
Synonyms:
Alternate IDs: 10054450
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Sirt3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 13-bp deletion in the Sirt3 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054450 Copy
The record is no longer available at this source.
Source Database: RGD, Rat Genome Database Strain List RGD
Genetic Background: mutant
Affected Genes: (null)
Genomic Alteration: (null)
Availability: Not Available
References:
Synonyms:
Alternate IDs:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Nlrp3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp deletion of exon 1 in the Nlrp3 gene. MCW Gene Editing Rat Resource Center This is a legacy resource.
Proper citation: RRID:RGD_12790673 Copy
The record is no longer available at this source.
Source Database: RGD, Rat Genome Database Strain List RGD
Genetic Background: mutant
Affected Genes: (null)
Genomic Alteration: (null)
Availability: Not Available
References:
Synonyms:
Alternate IDs:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Nlrp3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 10-bp deletion of exon 1 in the Nlrp3 gene. MCW Gene Editing Rat Resource Center This is a legacy resource.
Proper citation: RRID:RGD_12790669 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=401900749
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo (as of 2023-11-21)
References:
Synonyms:
Alternate IDs: RGD_401900749
Notes: CRISPR/Cas9 system was used to introduce a 272 bp deletion at the Prl7b1 locus Rat Resource and Research Center
Proper citation: 001014 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=617212698
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2025-07-16)
References:
Synonyms:
Alternate IDs: RGD_617212698
Notes: The rat Abca4 gene (Gene ID: 310836; GenBank accession number: NM_001107721.1) is located on rat chromosome 2. Exon 2 to exon 8 were selected as the target site for CRISPR/Cas9 modification on Sprague Dawley embryos. Rat Resource and Research Center
Proper citation: 001035 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=598092487
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2025-03-18)
References:
Synonyms:
Alternate IDs: RGD_598092487
Notes: A targeted 16 bp deletion was made in Exon 3 of the rat Cftr gene using CRISPR-Cas9 technology. Rat Resource and Research Center
Proper citation: 001038 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1358923
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 1358923
Notes: A spontaneous tremor rat was originated from in-house breeding colony , after purchased from Charles River Laboratory 12 years earlier, at McMaster University Central Animal Facility, Hamilton, Ontario, Canada. 10-12 days old rats had tremors that were followed by ataxia, hind limb paresis, episodes of immobility, and seizures by 5-14 weeks.
Proper citation: RRID:RGD_1358923 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1579690
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: 1579690
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. K196Stop is generated.
Proper citation: RRID:RGD_1579690 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1579677
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: 1579677
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. G120R mutation is generated.
Proper citation: RRID:RGD_1579677 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1579708
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: 1579708
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. S25T mutation is generated.
Proper citation: RRID:RGD_1579708 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1599768
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 1599768
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. V243I mutation is generated from the codon change GTC/ATC.
Proper citation: RRID:RGD_1599768 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1599766
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 1599766
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. L67R mutation is generated from the codon change CTG/CGG.
Proper citation: RRID:RGD_1599766 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1599765
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 1599765
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. I150N mutation is generated from the codon change ATC/AAC.
Proper citation: RRID:RGD_1599765 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1581636
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 1581636
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. E37G mutation is generated from the codon change GAG/GGG.
Proper citation: RRID:RGD_1581636 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1581637
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: 1581637
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. F55L mutation is generated from the codon change TTT/TTG.
Proper citation: RRID:RGD_1581637 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1581634
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct (as of 2016-10-24)
References:
Synonyms:
Alternate IDs: 1581634
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. C249S mutation is generated from the codon change TGT/AGT of rat Adora2a.
Proper citation: RRID:RGD_1581634 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1581624
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: 1581624
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. L347P mutation is generated from the codon change CTA/CCA.
Proper citation: RRID:RGD_1581624 Copy
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