Searching the RRID Resource Information Network
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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11667096
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: RGD_11667096, 11667096, RRRC_721, RRRC_0721, RRRC_00721
Notes: Male Wistar rats with inbred congenital unilateral right hydronephrosis were bred from the colony described in 1979 by Friedman et al. Rat Resource and Research Center
Proper citation: RRID:RRRC_00721 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14392784
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown (as of 2019-02-28)
References:
Synonyms:
Alternate IDs: RGD_14392784, 14392784, RRRC_849, RRRC_0849, RRRC_00849
Notes: This strain was produced by backcrossing the ZFN induced 482 deletion allele (Esr1em1Soar) in HsdHot:SD to the ACI/SegHsd background for 12 generations. ACI strain is particularly sensitive to Estrogen-induced tumorigenesis. Rat Resource and Research Center
Proper citation: RRID:RRRC_00849 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150519896
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: RGD_150519896, 150519896, RRRC_931, RRRC_0931, RRRC_00931
Notes: CRISPR/Cas9 mediated single nucleotide deletion resulting in a frameshift that creates a premature stop and generates a null allele. This strain serves as a model for Alexander disease - nulls are of interest for traumatic brain injury and many other studies of CNS disease and astrocyte response. Rat Resource and Research Center
Proper citation: RRID:RRRC_00931 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11667088
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: RGD_11667088, 11667088, RRRC_701, RRRC_0701, RRRC_00701
Notes: zinc finger nucleases were used to generate a 482 bp deletion in Esr1 gene, resulting in a knock out. Rat Resource and Research Center
Proper citation: RRID:RRRC_00701 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=12743630
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-02-10)
References:
Synonyms:
Alternate IDs: RGD_12743630, 12743630, RRRC_703, RRRC_0703, RRRC_00703
Notes: Retinae display marked rosett formation in the outer nuclear layer; in the funduscopy irregular, dark pigment flecks are observed, which cannot be identified in the histology. Linkage analysis indicating at least two genes interacting. Rat Resource and Research Center
Proper citation: RRID:RRRC_00703 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14398499
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2021-02-12)
References:
Synonyms:
Alternate IDs: RGD_14398499, 14398499, RRRC_856, RRRC_0856, RRRC_00856
Notes: The CRISPR system was used to created target insertion of iCre recombinase to the Drd1 (Drd1a) locus of the embryos of BluHsd:LE. Rat Resource and Research Center
Proper citation: RRID:RRRC_00856 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14398734
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2021-02-12)
References:
Synonyms:
Alternate IDs: RGD_14398734, 14398734, RRRC_857, RRRC_0857, RRRC_00857
Notes: The CRISPR system was used to created target insertion of iCre recombinase immediately after Adora2a gene, with P2A linker, of the embryos of BluHsd:LE. Rat Resource and Research Center
Proper citation: RRID:RRRC_00857 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11081177
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: RGD_11081177, 11081177, RRRC_749, RRRC_0749, RRRC_00749
Notes: A spontaneous tooth less mutation was maintained in inbred Fisher colony maintained at the University of Massachusetts Medical School. The homozygous mutant is a 10-bp insertion near the beginning of the open reading of the Csf1 gene that yields a truncated, nonfunctional protein and an early stop codon. Rat Resource and Research Center
Proper citation: RRID:RRRC_00749 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2314478
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Alternate IDs: RGD_2314478, 2314478, RRRC_392, RRRC_0392, RRRC_00392
Notes: ENU induced mutation in a Sprague Dawley rat resulting in a phenotypic change at the RT1.B MHC locus such that antibody binding to the RT1.B locus is no longer present. Animals carrying this mutation fail to have OX-6 antibody binding to the RT1.B locus. The exact nature of the mutation has not been genetically characterized. Mutation was backcrossed onto the Lewis strain. Rat Resource and Research Center
Proper citation: RRID:RRRC_00392 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=401900746
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2023-11-21)
References:
Synonyms:
Alternate IDs: RGD_401900746, 401900746, RRRC_1013, RRRC_01013
Notes: CRISPR/Cas9 system was used to introduce Cre recombinase downstream of the Prl7b1 start site. Rat Resource and Research Center
Proper citation: RRID:RRRC_01013 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=401900749
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo (as of 2023-11-21)
References:
Synonyms:
Alternate IDs: RGD_401900749, 401900749, RRRC_1014, RRRC_01014
Notes: CRISPR/Cas9 system was used to introduce a 272 bp deletion at the Prl7b1 locus Rat Resource and Research Center
Proper citation: RRID:RRRC_01014 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150523780
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2021-11-19)
References:
Synonyms:
Alternate IDs: RGD_150523780, 150523780, RRRC_918, RRRC_0918, RRRC_00918
Notes: The ZFN mRNA targeting exon 2 of Erap1 was microinjected into both the pronuclei and the cytoplasm of fertilized LEW eggs. This strain was heterozygous for a 2-bp deletion within the targeted AGGAGA sequence of Erap1. Rat Resource and Research Center
Proper citation: RRID:RRRC_00918 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2292453
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm
References:
Synonyms:
Alternate IDs: RGD_2292453, 2292453, RRRC_345, RRRC_0345, RRRC_00345
Notes: this Sleeping Beauty mutants were derived by crossing F344-Tg(T2/Bart3)2Ceb and F344-Tg(PGK2-SB11)Ceb Rat Resource & Research Center
Proper citation: RRID:RRRC_00345 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155641248
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: RGD_155641248, 155641248, RRRC_925, RRRC_0925, RRRC_00925
Notes: The CRISPR/Case9 knock-in rats have cre recombinase-dependent expression of nanoluciferase under the control of HIV LTR promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center
Proper citation: RRID:RRRC_00925 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155641247
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: RGD_155641247, 155641247, RRRC_926, RRRC_0926, RRRC_00926
Notes: The mutated ROSA26 locus of LE-(ROSA)26 em1(LTR-nLuc)Ottc (RGD:13208223) was crossed onto Fischer344 background by backcrossing the hybrid to Fischer344 and select for the presence of mutated locus. The LE donor is CRISPR/Case9 knock-in strain that has cre recombinase-dependent expression of nanoluciferase under the control of HIV LTR promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. now deposited at Rat Resource and Research Center
Proper citation: RRID:RRRC_00926 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290081
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm
References:
Synonyms:
Alternate IDs: RGD_2290081, 2290081, RRRC_367, RRRC_0367, RRRC_00367
Notes: this Sleeping Beauty mutants were derived by crossing F344-Tg(T2/Bart3)2Ceb and F344-Tg(PGK2-SB11)Ceb Rat Resource & Research Center
Proper citation: RRID:RRRC_00367 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290137
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm
References:
Synonyms:
Alternate IDs: RGD_2290137, 2290137, RRRC_361, RRRC_0361, RRRC_00361
Notes: this Sleeping Beauty mutants were derived by crossing F344-Tg(T2/Bart3)2Ceb and F344-Tg(PGK2-SB11)Ceb Rat Resource & Research Center
Proper citation: RRID:RRRC_00361 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155663560
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: RGD_155663560, 155663560, RRRC_983, RRRC_0983, RRRC_00983
Notes: CRISPR/Cas9 technology was used to insert an IRES for iCre expression after the final coding sequence of exon 6 of the rat Gcg gene, before the 3' UTR. Rat Resource and Research Center
Proper citation: RRID:RRRC_00983 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155900757
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown (as of 2023-12-19)
References:
Synonyms:
Alternate IDs: RGD_155900757, 155900757, RRRC_985, RRRC_0985, RRRC_00985
Notes: Using CRISPR/Cas9 genomic engineering in rats via homologous end-joining in fertilized embryos, we have knocked'in a humanized CHRNA6 3'UTR in place of the natural CHRNA6 3'UTR of the Sprague Dawley rat line. This new genetically modified CHRNA6C123G humanized rat line carries a homozygous CC nucleotide modification at position 123 within the CHRNA6 gene 3'UTR. The laboratory has deposited these strains with the Rat Resource and Research Center
Proper citation: RRID:RRRC_00985 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695058
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: RGD_14695058, 14695058, RRRC_792, RRRC_0792, RRRC_00792
Notes: frame shift deletion in an exon 12 of Add3 gene causing a stop codon and loss of function. SD outbred background. Rat Resource and Research Center
Proper citation: RRID:RRRC_00792 Copy
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