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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00034534
Source Database: WormBase (WB)
Availability: available
Source References: PMID:28394337
Synonyms: wdIs51; hrtEx53.
Alternate IDs: WB-STRAIN:STR199, CGC_STR199
Notes: wdIs51 [F49H12.4::GFP + unc-119(+)]; likely integrated in X. hrtEx53 [des-2p::mKate::GS1(low) + unc-119(+) + myo-2p::tdTomato]. Pick tdTomato+ animals to maintain. PVD development is somewhat affected by moderate levels of actin-perturbing DeAct-GS1 expression in PVD and FLP. Phenotype is less severe than that of the high DeAct-GS1 expressing strain STR198 and DeAct-SpvB expressing strain STR200. Reference: Harterink M, et al. J Cell Sci. 2018 Oct 22;131(20):jcs223107. PMID: 30254025.
Proper citation: RRID:WB-STRAIN:WBStrain00034534 Copy
http://www.wormbase.org/db/get?name=WBStrain00034540
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:26906482
Synonyms: unc-119(ed3); hrtEx66[Pwrt-2::mKate2::ePDZ; Pwrt-2::PH::gfp::LOVpep + cb-unc-119(+)]
Alternate IDs: WB-STRAIN:STR222
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00034540 Copy
http://www.wormbase.org/db/get?name=WBStrain00034545
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:26906482
Synonyms: unc-119(ed3); hrtSi24[Pgcy-36::tomm-20(aa1-41)::mKate2::LOVpep]; hrtEx78[Pgcy-36::unc-116 (aa1-381)::gfp::ePDZ; Pmyo-2::TdTomato]
Alternate IDs: WB-STRAIN:STR254
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00034545 Copy
http://www.wormbase.org/db/get?name=WBStrain00034634
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: mjIs11 III; mjIs17 IV.
Alternate IDs: WB-STRAIN:SX333, CGC_SX333
Notes: Made_by: Nicholas Lehrbach|"mjIs11 contains [myo-2::let-7 + unc-119(+)]. mjIs17contains [myo-2::GFP::lin-41 + myo-2::mCherry::unc-54 (let-7 sensor)]."
Proper citation: RRID:WB-STRAIN:WBStrain00034634 Copy
http://www.wormbase.org/db/get?name=WBStrain00034635
Source Database: WormBase (WB)
Affected Genes: WBGene00003504(mut-7)|WBGene00004010(pha-1)|WBGene00006768(unc-32)
Genomic Alteration: WBGene00003504(mut-7), WBGene00004010(pha-1), WBGene00006768(unc-32)
Availability: available
Source References: EMPTY
Synonyms: unc-32(e189) mut-7(pk204) pha-1(e2123) III; ccEx7271.
Alternate IDs: WB-STRAIN:SX340, CGC_SX340
Notes: ccEx7271 [let-858::GFP + pha-1(+)]. This strain expresses nuclear-localized GFP in all somatic nuclei, but reduced or no GFP in germ cells. If maintained at 20C, pha-1(ts) genotype will select for transgenic animals. Germ cell expression can be observed when maintained at 25C. Germline transgene silencing is abnormal.
Proper citation: RRID:WB-STRAIN:WBStrain00034635 Copy
http://www.wormbase.org/db/get?name=WBStrain00034630
Source Database: WormBase (WB)
Affected Genes: WBGene00004178(prg-1)|WBGene00004179(prg-2)|WBGene00006759(unc-22)
Genomic Alteration: WBGene00004178(prg-1), WBGene00004179(prg-2), WBGene00006759(unc-22)
Availability: available
Source References: EMPTY
Synonyms: prg-1(n4357) I; prg-2(n4358) unc-22(st136) IV.
Alternate IDs: WB-STRAIN:SX166, CGC_SX166
Notes: Mutagen:EMS(n4357 & n4358) Curator_confirmed WBPerson1983|"Transposon silencing normal."
Proper citation: RRID:WB-STRAIN:WBStrain00034630 Copy
http://www.wormbase.org/db/get?name=WBStrain00034631
Source Database: WormBase (WB)
Affected Genes: WBGene00004178(prg-1)|WBGene00006759(unc-22)
Genomic Alteration: WBGene00004178(prg-1), WBGene00006759(unc-22)
Availability: available
Source References: EMPTY
Synonyms: prg-1(n4357) I; unc-22(r765) IV.
Alternate IDs: WB-STRAIN:SX178, CGC_SX178
Notes: Mutagen:EMS/Tc4|"Twitching due to transposon insertion in unc-22."
Proper citation: RRID:WB-STRAIN:WBStrain00034631 Copy
http://www.wormbase.org/db/get?name=WBStrain00034633
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: mjIs17 IV.
Alternate IDs: WB-STRAIN:SX328, CGC_SX328
Notes: Made_by: Nicholas Lehrbach|"mjIs17 contains [myo-2::GFP::lin-41 + myo-2::mCherry::unc-54 (let-7 sensor)]."|"mjIs17contains [myo-2::GFP::lin-41 + myo-2::mCherry:unc-54 (let-7 sensor)]."
Proper citation: RRID:WB-STRAIN:WBStrain00034633 Copy
http://www.wormbase.org/db/get?name=WBStrain00034646
Source Database: WormBase (WB)
Affected Genes: WBGene00008995(prde-1)
Genomic Alteration: WBGene00008995(prde-1)
Availability: available
Source References: EMPTY
Synonyms: prde-1(mj207) V.
Alternate IDs: WB-STRAIN:SX2499, CGC_SX2499
Notes: piRNA biogenesis mutant. Reduced brood size. Maintain at 20C. Reference: Weick EM, et al. Genes Dev. 2014 Apr 1;28(7):783-96.
Proper citation: RRID:WB-STRAIN:WBStrain00034646 Copy
http://www.wormbase.org/db/get?name=WBStrain00034642
Source Database: WormBase (WB)
Affected Genes: WBGene00004178(prg-1)
Genomic Alteration: WBGene00004178(prg-1)
Availability: available
Source References: PMID:31402283, PMID:33086057
Synonyms: prg-1(n4357) I.
Alternate IDs: WB-STRAIN:SX922, CGC_SX922
Notes: 21U RNA expression abnormal. Temperature sensitive sterility. Transposon silencing abnormal. Superficially WT. Deletion breakpoints: GTTTTCTTTCCTTGGAGAGGT|"no longer available from the CGC."
Proper citation: RRID:WB-STRAIN:WBStrain00034642 Copy
http://www.wormbase.org/db/get?name=WBStrain00034612
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; heIs105 IV.
Alternate IDs: WB-STRAIN:SV1361, CGC_SV1361
Notes: heIs105 [rps-27::loxP::NLS::mCherry::let858 UTR::loxP::NLS::GFP::let-858 UTR + unc-119(+)] IV. Strain is viable at 15-25 C. heIs105 carries a read-out construct which allows the visualization of the CRE lox mediated recombination by a switch from red to green. Reference: Ruijtenberg S & van den Heuvel S. Cell. 2015 Jul 16;162(2):300-13.
Proper citation: RRID:WB-STRAIN:WBStrain00034612 Copy
http://www.wormbase.org/db/get?name=WBStrain00034613
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; heSi141 X.
Alternate IDs: WB-STRAIN:SV1438, CGC_SV1438
Notes: heSi141 [hlh-8(short)::FLAG::CRE::tbb-2 + unc-119(+)] X. Strain is viable at 15-25 C, but non-tissue specific recombination is observed more frequently in other tissues at higher temperatures (25C). Expression of CRE recombinase in the mesoblast lineage driven by the hlh-8 promoter. Reference: Ruijtenberg S & van den Heuvel S. Cell. 2015 Jul 16;162(2):300-13.
Proper citation: RRID:WB-STRAIN:WBStrain00034613 Copy
http://www.wormbase.org/db/get?name=WBStrain00034614
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; heSi142 X.
Alternate IDs: WB-STRAIN:SV1439, CGC_SV1439
Notes: heSi142 [elt-2::FLAG::CRE::tbb-2 + unc-119(+)] X. Expression of CRE recombinase in the intestine driven by the elt-2 promoter. Strain is viable at 15-25 C, but non-tissue specific recombination is observed more frequently in other tissues at higher temperatures (25C). Reference: Ruijtenberg S & van den Heuvel S. Cell. 2015 Jul 16;162(2):300-13.
Proper citation: RRID:WB-STRAIN:WBStrain00034614 Copy
http://www.wormbase.org/db/get?name=WBStrain00034617
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; heIs145 IV
Alternate IDs: WB-STRAIN:SV1450, CGC_SV1450
Notes: heIs145 [rps-27::loxP::NLS::mCherry::let858 UTR::eft-3::tagBFP::tbb-2 UTR::loxP::NLS::GFP::let-858 UTR + unc-119(+)] IV. Maintain at 15-25C. heIs145 expresses a read-out construct used to visualize CRE activity and specificity, and to test whether CRE expression is likely to induce loss of a gene of interest (tagBFP in this case) in a given tissue. Expression of CRE will result in a change from mCherry to GFP and loss of tagBFP expression in those cells where CRE is active. Reference: Ruijtenberg S & van den Heuvel S. Cell. 2015 Jul 16;162(2):300-13.
Proper citation: RRID:WB-STRAIN:WBStrain00034617 Copy
http://www.wormbase.org/db/get?name=WBStrain00034618
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: EMPTY
Synonyms: unc-119(ed3) III; heSi148 X.
Alternate IDs: WB-STRAIN:SV1461
Notes: heSi148 [myo-3::CRE::tbb-2 UTR + unc-119(+)] X. Inserted at ttTi14024. Maintain at 15-25C. Expression of CRE recombinase in differentiated body wall muscle cells driven by the myo-3 promoter. Reference: Ruijtenberg S & van den Heuvel S. Cell. 2015 Jul 16;162(2):300-13.|"No longer available from the CGC"
Proper citation: RRID:WB-STRAIN:WBStrain00034618 Copy
http://www.wormbase.org/db/get?name=WBStrain00034692
Source Database: WormBase (WB)
Affected Genes: WBGene00001052(dop-1)|WBGene00001053(dop-2)|WBGene00020506(dop-3)
Genomic Alteration: WBGene00001052(dop-1), WBGene00001053(dop-2), WBGene00020506(dop-3)
Availability: available
Source References: EMPTY
Synonyms: vtIs1 dop-2(vs105) V; dop-1(vs100) dop-3(vs106) X.
Alternate IDs: WB-STRAIN:TG2415, CGC_TG2415
Notes: vtIs1 [dat-1p::GFP + rol-6(su1006)] V. Rollers. Reference: Masoudi N, et al. PLoS Genet. 2014 Dec 4;10(12):e1004767.
Proper citation: RRID:WB-STRAIN:WBStrain00034692 Copy
http://www.wormbase.org/db/get?name=WBStrain00034694
Source Database: WormBase (WB)
Availability: available
Source References: PMID:36719882, PMID:37528117, PMID:39950089, PMID:39746999
Synonyms: vtIs1 V.
Alternate IDs: WB-STRAIN:TG2435, CGC_TG2435
Notes: vtIs1 [dat-1p::GFP + rol-6(su1006)] V. Strain does not roll well, but GFP expression is easily detected. Reference: Nass R, et al. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3264-9. Masoudi N, et al. PLoS Genet. 2014 Dec 4;10(12):e1004767.
Proper citation: RRID:WB-STRAIN:WBStrain00034694 Copy
http://www.wormbase.org/db/get?name=WBStrain00034697
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00008140(xpf-1)|WBGene00016602(mus-81)
Genomic Alteration: WBGene00000254(bli-4), WBGene00008140(xpf-1), WBGene00016602(mus-81)
Availability: available
Source References: EMPTY
Synonyms: mus-81(tm1937) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); xpf-1(tm2842) II; gtIs2512.
Alternate IDs: WB-STRAIN:TG2452, CGC_TG2452
Notes: gtIs2512 [pie-1p::his-11::GFP + unc-119(+)]. Segregates WT GFP+ heterozygotes, non-GFP mus-81; xpf-1 double homozygotes, very rare GFP+ homozygous hT2, and dead eggs. Maintain by picking wild-type GFP+ to retain balanced strain: 15-25% of mus-81; xpf-1 double homozygotes are viable. unc-119(ed3) has likely been lost through outcrossing, but could still be present in the background. Reference: Agostinho A, et al. PLos Genetics 2013.
Proper citation: RRID:WB-STRAIN:WBStrain00034697 Copy
http://www.wormbase.org/db/get?name=WBStrain00034611
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: heSi101 I; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:SV1317, CGC_SV1317
Notes: heSi101 [tcc-1p::tcc-1::mCherry::tcc-1 3' UTR + Cbr-unc-119(+)] I. TCC-1::mCherry associates with the mitotic spindle, nuclear envelope, and plasma membrane. Reference: Berends CWH, et al. Mol Biol Cell. 2013 Jul;24(14):2201-15.|"no longer available from the CGC."
Proper citation: RRID:WB-STRAIN:WBStrain00034611 Copy
http://www.wormbase.org/db/get?name=WBStrain00034623
Source Database: WormBase (WB)
Affected Genes: WBGene00000962(dhc-1)
Genomic Alteration: WBGene00000962(dhc-1)
Availability: available
Source References: EMPTY
Synonyms: dhc-1(he264[eGFP::dhc-1]) I.
Alternate IDs: WB-STRAIN:SV1803, CGC_SV1803
Notes: This strain carries endogenously tagged dynein heavy chain (egfp::dhc-1). Reference: Schmidt et al., J Cell Biol. 2017 Sep 4; 216(9): 27772793. doi: 10.1083/jcb.201607038
Proper citation: RRID:WB-STRAIN:WBStrain00034623 Copy
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