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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00034434
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006936(glp-4)
Genomic Alteration: WBGene00006936(glp-4)
Availability: available
References:
Synonyms: glp-4(bn2) I.
Alternate IDs: WB-STRAIN:SS104, CGC_SS104
Notes: Reference WBPaper00056840 added based on published strain data identified by Textpresso literature search.|"Reference WBPaper00059681 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00060516 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype glp-4(bn2ts) I"|"Temperature sensitive defect in germ-line proliferation during larval development. Defect can be reversed by shifting worms from restrictive (25C) to permissive temperature (16C). Germ-line proliferation defect at restrictive temperature may be due to arrest in mitotic prophase. This strain is very useful for producing large populations of worms that essentially lack a germ line."|"WBStrain mapped, WBPaper00061562 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00034434 Copy
http://www.wormbase.org/db/get?name=WBStrain00034435
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003219(mes-1)
Genomic Alteration: WBGene00003219(mes-1)
Availability: available
References:
Synonyms: mes-1(bn7) X.
Alternate IDs: WB-STRAIN:SS149, CGC_SS149
Notes: Temperature-sensitive. Maintain at 15C. The embryos from homozygous mutant mothers display defects in the unequal cell divisions of P2 and P3, defects in partitioning of germ granules during these divisions, and defects in formation of the germ-line precursor cell P4. The embryos that lack P4 develop into sterile adults. These defects are incompletely expressed and sensitive to temperature. Homozygous mothers produce about 10% sterile progeny at 16C and 70% sterile progeny at 25C. The temperature-sensitive period is early in embryogenesis, from fertilization to about the 28-cell stage. See also WBPaper00002282.
Proper citation: RRID:WB-STRAIN:WBStrain00034435 Copy
http://www.wormbase.org/db/get?name=WBStrain00034449
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001862(him-3)|WBGene00003992(pgl-1)|WBGene00003994(pgl-3)
Genomic Alteration: WBGene00001862(him-3), WBGene00003992(pgl-1), WBGene00003994(pgl-3)
Availability: available
References:
Synonyms: pgl-1(ct131) him-3(e1147) IV; pgl-3(bn104) V.
Alternate IDs: WB-STRAIN:SS618, CGC_SS618
Notes: Mutagen:UV/TMP|"Throws males. Mostly sterile at all temperatures, but a small fraction are fertile at low temperatures. Maintain at 15C."
Proper citation: RRID:WB-STRAIN:WBStrain00034449 Copy
http://www.wormbase.org/db/get?name=WBStrain00034441
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001079(dpy-20)|WBGene00003224(mes-6)
Genomic Alteration: WBGene00001079(dpy-20), WBGene00003224(mes-6)
Availability: available
References:
Synonyms: mes-6(bn66) dpy-20(e1282) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:SS360, CGC_SS360
Notes: Heterozygotes are Unc (n754 is dominant Unc and recessive lethal). Hets throw Dpys which give only sterile progeny. The maternal effect sterility is 99% expressed, 100% strict, and is associated with 1% maternal effect embryonic lethality.|"Made_by: C. Gavin & C. Scanga"
Proper citation: RRID:WB-STRAIN:WBStrain00034441 Copy
http://www.wormbase.org/db/get?name=WBStrain00034442
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003992(pgl-1)
Genomic Alteration: WBGene00003992(pgl-1)
Availability: available
References:
Synonyms: pgl-1(bn101) IV.
Alternate IDs: WB-STRAIN:SS579, CGC_SS579
Notes: Temperature sensitive sterility. The sterility has both a maternal and a non-maternal component. Can be maintained indefinitely at low temperatures (16-23 C), with 7-19% sterile offspring. When low-temperature-grown homozygotes are allowed to produce progeny at 25C, the percentage of sterile offspring is 75-85%; at 26C the percentage of sterile offspring is 100%.
Proper citation: RRID:WB-STRAIN:WBStrain00034442 Copy
http://www.wormbase.org/db/get?name=WBStrain00034443
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003992(pgl-1)
Genomic Alteration: WBGene00003992(pgl-1)
Availability: available
References:
Synonyms: pgl-1(bn102) IV.
Alternate IDs: WB-STRAIN:SS580, CGC_SS580
Notes: Temperature sensitive sterility. The sterility has both a maternal and a non-maternal component. Can be maintained indefinitely at low temperatures (16-23 C), with 7-19% sterile offspring. When low-temperature-grown homozygotes are allowed to produce progeny at 25C, the percentage of sterile offspring is 75-85%; at 26C the percentage of sterile offspring is 100%.
Proper citation: RRID:WB-STRAIN:WBStrain00034443 Copy
http://www.wormbase.org/db/get?name=WBStrain00034445
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003994(pgl-3)
Genomic Alteration: WBGene00003994(pgl-3)
Availability: available
References:
Synonyms: pgl-3(bn104) V.
Alternate IDs: WB-STRAIN:SS608, CGC_SS608
Notes: Fertile at all temperatures.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00034445 Copy
http://www.wormbase.org/db/get?name=WBStrain00034446
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001073(dpy-11)|WBGene00003994(pgl-3)
Genomic Alteration: WBGene00001073(dpy-11), WBGene00003994(pgl-3)
Availability: available
References:
Synonyms: pgl-3(bn104) dpy-11(e224) V.
Alternate IDs: WB-STRAIN:SS609, CGC_SS609
Notes: Dpy. Fertile at all temperatures.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00034446 Copy
http://www.wormbase.org/db/get?name=WBStrain00034414
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004895(smu-1)|WBGene00006772(unc-36)
Genomic Alteration: WBGene00004895(smu-1), WBGene00006772(unc-36)
Availability: available
References:
Synonyms: smu-1(mn415) I; unc-36(e251) III; mnEx156.
Alternate IDs: WB-STRAIN:SP2688, CGC_SP2688
Notes: mnEx156 [smu-2::GFP + smu-1::3xHA + unc-36(+)( R1p16)]. Maintain by picking non-Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00034414 Copy
http://www.wormbase.org/db/get?name=WBStrain00034415
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004896(smu-2)|WBGene00006772(unc-36)|WBGene00006787(unc-52)
Genomic Alteration: WBGene00004896(smu-2), WBGene00006772(unc-36), WBGene00006787(unc-52)
Availability: available
References:
Synonyms: smu-2(mn416) unc-52(e669su250) II; unc-36(e251) III; mnIs66.
Alternate IDs: WB-STRAIN:SP2693, CGC_SP2693
Notes: Made_by: A Spartz & R Herman|"mnIs66 [smu-2::HA + unc-36(+)]. Strain should be non-Unc-36 and should be Unc-52 (paralyzed, except for head, as late L4/adult - they look like hockey sticks) at 25 C. Reference: Spartz AK, et al. Mol Cell Biol. 2004 Aug;24(15):6811-23."
Proper citation: RRID:WB-STRAIN:WBStrain00034415 Copy
http://www.wormbase.org/db/get?name=WBStrain00034416
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003172(mec-8)|WBGene00003559(ncl-1)|WBGene00006368(sym-3)|WBGene00006772(unc-36)
Genomic Alteration: WBGene00003172(mec-8), WBGene00003559(ncl-1), WBGene00006368(sym-3), WBGene00006772(unc-36)
Availability: available
References:
Synonyms: mec-8(u74) I; ncl-1(e1865) gon-1(e2551) III; sym-3(mn618) X; mnEx169.
Alternate IDs: WB-STRAIN:SP2729, CGC_SP2729
Notes: mnEx169 [sym-3(+) + pTG96(sur-5::GFP)]. Pick GFP+ to maintain.
Proper citation: RRID:WB-STRAIN:WBStrain00034416 Copy
http://www.wormbase.org/db/get?name=WBStrain00034418
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00013835(mlt-4)
Genomic Alteration: WBGene00013835(mlt-4)
Availability: available
References:
Synonyms: mlt-4(sv9) V; mnEx173.
Alternate IDs: WB-STRAIN:SP2734, CGC_SP2734
Notes: mnEx173 [ZC15 (mlt-4(+)) + pTG96 (sur-5::GFP)]. Pick GFP+ to maintain.
Proper citation: RRID:WB-STRAIN:WBStrain00034418 Copy
http://www.wormbase.org/db/get?name=WBStrain00034419
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004804(skn-1)
Genomic Alteration: WBGene00004804(skn-1)
Availability: available
References:
Synonyms: dvIs19 III; skn-1(lax120) IV.
Alternate IDs: WB-STRAIN:SPC167, CGC_SPC167
Notes: dvIs19 [(pAF15) gst-4p::GFP::NLS] III. Oxidative stress-inducible GFP. Sma. Dominant allele of skn-1 is constitutively active and does not respond to dietary restriction. Reference: Paek J, et al. Cell Metab. 2012 Oct 3;16(4):526-37.
Proper citation: RRID:WB-STRAIN:WBStrain00034419 Copy
http://www.wormbase.org/db/get?name=WBStrain00034494
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: ncEx2365.
Alternate IDs: WB-STRAIN:ST2365, CGC_ST2365
Notes: ncEx2365 [del-1p::Arch::eGFP + (pCFJ90) myo-2p::mCherry]. Pick GFP+ animals to maintain. Reference: Okazaki A, et al. PLoS One. 2012;7(5):e35370.
Proper citation: RRID:WB-STRAIN:WBStrain00034494 Copy
http://www.wormbase.org/db/get?name=WBStrain00034496
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: ncEx3003.
Alternate IDs: WB-STRAIN:ST3003, CGC_ST3003
Notes: ncEx3003 [(pPD49.78) hsp16-2p::Arch::eGFP + (pRF4) rol-6(su1006)]. Pick GFP+ animals to maintain. Reference: Okazaki A, et al. PLoS One. 2012;7(5):e35370.|"ncEx3003 [hsp16-2p::Arch::eGFP + rol-6(su1006)]. Pick GFP+ animals to maintain. Reference: Okazaki A, et al. PLoS One. 2012;7(5):e35370."
Proper citation: RRID:WB-STRAIN:WBStrain00034496 Copy
http://www.wormbase.org/db/get?name=WBStrain00034497
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: ncEx3026.
Alternate IDs: WB-STRAIN:ST3026, CGC_ST3026
Notes: ncEx3026 [aex-3p::Arch::eGFP + (pRF4) rol-6(su1006)]. Pick GFP+ animals to maintain. Reference: Okazaki A, et al. PLoS One. 2012;7(5):e35370.|"ncEx3026 [aex-3p::Arch::eGFP + rol-6(su1006)]. Pick GFP+ animals to maintain. Reference: Okazaki A, et al. PLoS One. 2012;7(5):e35370."
Proper citation: RRID:WB-STRAIN:WBStrain00034497 Copy
http://www.wormbase.org/db/get?name=WBStrain00034498
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: available
References:
Synonyms: ncEx3031.
Alternate IDs: WB-STRAIN:ST3031, CGC_ST3031
Notes: ncEx3031 [myo-3p::Arch::eGFP + (pRF4) rol-6(su1006)]. Pick GFP+ animals to maintain. Reference: Okazaki A, et al. PLoS One. 2012;7(5):e35370.|"ncEx3031 [myo-3p::Arch::eGFP + rol-6(su1006)]. Pick GFP+ animals to maintain. Reference: Okazaki A, et al. PLoS One. 2012;7(5):e35370."
Proper citation: RRID:WB-STRAIN:WBStrain00034498 Copy
http://www.wormbase.org/db/get?name=WBStrain00034413
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004896(smu-2)|WBGene00006772(unc-36)|WBGene00006787(unc-52)
Genomic Alteration: WBGene00004896(smu-2), WBGene00006772(unc-36), WBGene00006787(unc-52)
Availability: available
References:
Synonyms: smu-2(mn416) unc-52(e669su250) II; unc-36(e251) III; mnEx151.
Alternate IDs: WB-STRAIN:SP2686, CGC_SP2686
Notes: Made_by: A Spartz & R Herman|"mnEx151 [smu-1::GFP + smu-2::3xHA + unc-36(+)]. Animals carrying the array should be non-Unc-36 and should be Unc-52 (paralyzed, except for head, as late L4/adult - they look like hockey sticks) at 25 C. Without the array smu-2(mn416) suppresses unc-52(e669su250) so animals don't show the Unc-52 phenotype. Reference: Spartz AK, et al. Mol Cell Biol. 2004 Aug;24(15):6811-23."
Proper citation: RRID:WB-STRAIN:WBStrain00034413 Copy
http://www.wormbase.org/db/get?name=WBStrain00034426
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001803(lite-1)|WBGene00004010(pha-1)
Genomic Alteration: WBGene00001803(lite-1), WBGene00004010(pha-1)
Availability: available
References:
Synonyms: pha-1(e2123) III; lite-1(ce314) X; sraEx279.
Alternate IDs: WB-STRAIN:SRS279, CGC_SRS279
Notes: sraEx279 [ttx-3p::Arch::TagRFP + pBX(pha-1(+))]. Maintain at 25C. This transgenic line expresses TagRFP in AIY and has little response to blue light in the absence of ATR. In the presence of ATR the reversal rate of the animal is increased upon symmetrical stimulation, and asymmetrical stimulation causes the worm to turn in the opposite direction to which the head was bent when AIY was excited. Reference: Kocabas A, et al. Nature. 2012 Sep 23. doi: 10.1038/nature11431.
Proper citation: RRID:WB-STRAIN:WBStrain00034426 Copy
http://www.wormbase.org/db/get?name=WBStrain00034424
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001803(lite-1)|WBGene00004010(pha-1)
Genomic Alteration: WBGene00001803(lite-1), WBGene00004010(pha-1)
Availability: available
References:
Synonyms: pha-1(e2123) III; lite-1(ce314) X; sraEx230.
Alternate IDs: WB-STRAIN:SRS230, CGC_SRS230
Notes: sraEx230 [str-2p::Arch::TagRFP + pBX(pha-1(+))]. Maintain at 25C. This transgenic line expresses TagRFP in AWC(on) and has little response to blue light in the absence of ATR. In the presence of ATR the reversal rate of the animal is decreased upon symmetrical stimulation, and asymmetrical stimulation causes the worm to turn in the same direction the head was bent when AWC(on) was inhibited. Reference: Kocabas A, et al. Nature. 2012 Sep 23. doi: 10.1038/nature11431.
Proper citation: RRID:WB-STRAIN:WBStrain00034424 Copy
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