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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Commercial antibody supplier and developer for biomedical research. These products are compatible with use in flow cytometry and mass cytometry, immunoprecipitation and chip, western blotting, immunofluorescence microscopy, and quantitative multiplexing.
Proper citation: BioLegend (RRID:SCR_001134) Copy
Commercial supplier which provides antibodies, assay kits, biomarkers, and proteins.
Proper citation: NewEast Biosciences (RRID:SCR_001129) Copy
Public university in Utah, USA that provides undergraduate, master's, post graduate, graduate, and professional degree programs.
Proper citation: University of Utah; Utah; USA (RRID:SCR_001003) Copy
A federally chartered, private, coeducational, nonsectarian, historically black university in Washington, D.C. Howard University has graduate schools in many fields, including business, nursing, engineering, and medicine.
Proper citation: Howard University; Washington D.C. (RRID:SCR_001084) Copy
https://code.google.com/p/jmzml/
A Java application programming interface (API) for the Proteomics Standards Initiative mzML data standard.
Proper citation: jmzML (RRID:SCR_001119) Copy
http://bioconductor.org/packages/devel/bioc/html/massiR.html
Software that predicts the sex of samples in gene expression microarray datasets.
Proper citation: massiR (RRID:SCR_001157) Copy
https://www.phoenixpeptide.com/
Commercial antibody supplier that specializes in peptide-related products for research in obesity, cardiovascular disease, and diabetes.
Proper citation: Phoenix Pharmaceuticals (RRID:SCR_001141) Copy
http://www.ebi.ac.uk/~stijn/reaper/reaper.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23, 2022. Software program for demultiplexing, trimming and filtering short read sequencing data.
Proper citation: Reaper - Demultiplexing trimming and filtering sequencing data (RRID:SCR_001144) Copy
https://rdrr.io/bioc/yaqcaffy/
Software package for quality control of Affymetrix GeneChip expression data and reproducibility analysis of human whole genome chips with the MAQC reference datasets.
Proper citation: yaqcaffy (RRID:SCR_001295) Copy
Software to mimic various methylation level and bisulfite conversion rate in CpG, CHG and CHH context, respectively. It can also simulate genetic variations that are divergent from the reference sequence along with the sequencing error and quality distributions. In the output, both directional/non-directional, various read length, single/paired-end reads and alignment data in the SAM format can be generated. BSSim is a cross-platform BS-seq simulator offers output read datasets not only suitable for Illumina's Solexa, but also for Roche's 454 and Applied Biosystems' SOLiD.
Proper citation: BSSim (RRID:SCR_001212) Copy
http://montgomerylab.stanford.edu/spliceplot/index.html
A software tool for visualizing alternative splicing and the effects of splicing quantitative trait loci (sQTLs) from RNA-seq data. It provides a simple command line interface for drawing sashimi plots, hive plots, and structure plots of alternative splicing events from .bam, .gtf, and .vcf files.
Proper citation: SplicePlot (RRID:SCR_001172) Copy
http://www.bioconductor.org/packages/release/bioc/html/ChIPsim.html
Software package providing a general framework for the simulation of ChIP-seq data. Although currently focused on nucleosome positioning the package is designed to support different types of experiments.
Proper citation: ChIPsim (RRID:SCR_001293) Copy
http://www.bioconductor.org/packages/release/bioc/html/methyAnalysis.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package for DNA methylation data analysis and visualization. A new class is defined to keep the chromosome location information together with the data. The current version of the package mainly focuses on analyzing the Illumina Infinium methylation array data, but most methods can be generalized to other methylation array or sequencing data.
Proper citation: methyAnalysis (RRID:SCR_001290) Copy
http://julian-gehring.github.io/les/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package that estimates Loci of Enhanced Significance (LES) in tiling microarray data. These are regions of regulation such as found in differential transcription, CHiP-chip, or DNA modification analysis. The package provides a universal framework suitable for identifying differential effects in tiling microarray data sets, and is independent of the underlying statistics at the level of single probes.
Proper citation: les (RRID:SCR_001291) Copy
http://qualimap.bioinfo.cipf.es/
Software application written in Java and R that provides both a Graphical User Inteface (GUI) and a command-line interface to facilitate the quality control of alignment sequencing data. It examines sequencing alignment data in SAM / BAM files according to the features of the mapped reads and provides an overall view of the data that helps to the detect biases in the sequencing and/or mapping of the data and eases decision-making for further analysis.
Proper citation: QualiMap (RRID:SCR_001209) Copy
http://www.cs.ucr.edu/~tanaseio/metaphyl.htm
Software implementing a supervised classification method for metagenomic samples that takes advantage of the natural structure of microbial community data encoded by phylogenetic trees.
Proper citation: MetaPhyl (RRID:SCR_001169) Copy
https://www.bioconductor.org/packages//2.10/bioc/html/beadarraySNP.html
Software package for importing data from Illumina SNP experiments and performing copy number calculations and reports.
Proper citation: beadarraySNP (RRID:SCR_001281) Copy
http://josephryan.github.io/baa.pl/
Software tool to evaluate de novo genome assemblies with RNA transcripts.
Proper citation: Baa.pl (RRID:SCR_001197) Copy
http://pathology.wustl.edu/VirusHunter/
A fully automated and modular software package for mining sequence data to identify sequences of microbial origin. The pipeline was optimized for analysis of data generated by the Roche/454 next-generation sequencing platform but can be applied to longer sequences (Sanger sequencing data or assembled contigs) as well. Microbial sequences are identified on the basis of BLAST alignments and the taxonomic classification of the reference sequence(s) to which a read is aligned. Viruses are the focal point of VirusHunter as released, but it can be easily modified to generate parallel outputs for bacterial or parasitic species. To date, VirusHunter has been applied to thousands of specimens, including human, animal and environmental samples, resulting in the detection of many known and novel viruses.
Proper citation: VirusHunter (RRID:SCR_001198) Copy
http://www.biobase-international.com/product/genome-trax
Service that provides a comprehensive compilation of variant knowledge that allows you to identify pathogenic variants in human whole genome or exome sequences. It makes it easy to upload a complete genome?s worth of variations and identify the biologically relevant subset of known mutations, mutations that are novel and appear in a candidate disease genes, or mutations that are predicted to have a deleterious effect. The database includes a comprehensive collection of disease causing mutations from HGMD Professional, regulatory sites from TRANSFAC , and disease genes, drug targets and pathways from PROTEOME, as well as pharmacogenomic variants. It integrates the best public data-sets on somatic mutations, allele frequencies and clinical variants, in their most up-to-date version, for a total of more than 165 million annotations. It is possible to identify known pathogenic variants, remove harmless common variants, and obtain deleterious predictions for novel variants. With family data, it is possible to identify variants that are de novo, compound heterozygous only in the offspring. All of the results can be downloaded to Excel for further review. For core facilities and bioinformaticians, the complete underlying data is made available for download and easy integration into custom analysis pipelines. Genome Trax data is optimized to work with many other software packages, such as ANNOVARTM, CLC bio, Alamut, SimulConsult, and Cartagenia.
Proper citation: Genome Trax (RRID:SCR_001234) Copy
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