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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/release/bioc/html/MergeMaid.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 18,2025. R extension whose functions are intended for cross-study comparison of gene expression array data. Required from the user is gene expression matrices, their corresponding gene-id vectors and other useful information, and they could be "list", "matrix", or "ExpressionSet". The main function is "mergeExprs" which transforms the input objects into data in the merged format, such that common genes in different datasets can be easily found. And the function "intcor" calculate the correlation coefficients. Other functions use the output from "modelOutcome" to graphically display the results and cross-validate associations of gene expression data with survival.
Proper citation: MergeMaid (RRID:SCR_001221) Copy
Software tool for exploring patterns in Chromatin Immuno Precipitation (ChIP) profiling data. The CATCH algorithm performs a hierachical clustering of the profile patterns with an exhaustive alignment at each step. The algorithm has a user-friendly graphical interface that makes it easy to browse results.
Proper citation: CATCHprofiles (RRID:SCR_001182) Copy
http://sourceforge.net/apps/mediawiki/breakway/index.php
A suite of software programs that take aligned genomic data and report structural variation breakpoints. Features include: * Takes in BAM formatted input, the current standard for genomic alignments. * Compatible with standard output from major alignment algorithms such as BFAST, BWA, MAQ, et cetera. * Capable of analyzing data from any major platform--Solexa, SOLiD, 454, et cetera. * Empirically identifies structural variation breakpoints. * Highly specific analysis generates very few false positives. * Includes a suite of downstream tools for annotating identified breakpoints and reducing false positives.
Proper citation: Breakway (RRID:SCR_001180) Copy
http://genomics1.mh-hannover.de/genometa/index.php?Site=Home
A Java based bioinformatics program which allows rapid analysis of metagenomic short read datasets. Millions of short reads can be accurately analysed within minutes and visualised in the browser component. A large database of diverse bacteria and archaea has been constructed as a reference sequence. The approach is based upon the established open source visualisation tool IGB and supported by the rapid alignment program bowtie. The Picard toolset for SAM files is also made use of.
Proper citation: Genometa (RRID:SCR_001181) Copy
http://www.webcitation.org/getfile?fileid=05c70eb653a3b267453212d27dd8ac8c211c0f96
Application that provides users an interface to design analysis protocols combining one or more normalization and filtering steps. In this way, data from many individual hybridizations can be treated in a uniform and reproducible manner.
Proper citation: Microarray Data Analysis System (RRID:SCR_001218) Copy
http://www.bioconductor.org/packages/release/bioc/html/iterativeBMAsurv.html
Software package providing a variable selection method for applying survival analysis to microarray data.
Proper citation: iterativeBMAsurv (RRID:SCR_001254) Copy
http://www.bioconductor.org/packages/release/bioc/html/snpStats.html
Software for classes and statistical methods for large single nucleotide polymorphism (SNP) association studies.
Proper citation: snpStats: SnpMatrix and XSnpMatrix classes and methods (RRID:SCR_001249) Copy
https://sites.google.com/site/vibansal/software/picall
Software to detect short insertion / deletion variants (and SNPs) from population sequence data, i.e. sequence reads generated from a population of individuals. It uses a probabilistic model to utilize sequence reads from a population of individuals to automatically account for context-specific sequencing errors associated with indels. piCALL is implemented in C for use on Linux platforms and can be applied to sequence data from different sequencing platforms. However, the method requires each individual in a dataset to be sequenced using the same platform. The reads for each individual should be aligned to the same reference genome sequence. Note that the program will not be able to call indels from individual sequence datasets or data from a small number of individuals.
Proper citation: piCALL (RRID:SCR_001242) Copy
http://ginolhac.github.io/mapDamage/
Software for tracking and quantifying DNA damage patterns among ancient DNA sequencing reads generated by Next-Generation Sequencing platforms.
Proper citation: mapDamage (RRID:SCR_001240) Copy
Software utility for counting k-mers (sequences of consecutive k symbols) in a set of reads from genome sequencing projects. It scans the raw reads and produces a compact representation of all non-unique reads accompanied with number of their occurrences. The algorithm implemented makes use mostly of disk space rather than RAM, which allows to use KMC even on rather typical personal computers.
Proper citation: KMC (RRID:SCR_001245) Copy
http://minia.genouest.org/dsk/
A k-mer counting software that can count k-mers of large Illumina datasets on laptops and desktop computers.
Proper citation: DSK (RRID:SCR_001246) Copy
https://bioconductor.org/packages//2.12/bioc/html/exomeCopy.html
Software package for detection of copy number variants (CNV) from exome sequencing samples, including unpaired samples. The package implements a hidden Markov model which uses positional covariates, such as background read depth and GC-content, to simultaneously normalize and segment the samples into regions of constant copy count.
Proper citation: exomeCopy (RRID:SCR_001276) Copy
http://www.bioconductor.org/packages/2.14/bioc/html/SMAP.html
Software package providing functions and classes for DNA copy number profiling of array-CGH data.
Proper citation: SMAP (RRID:SCR_001270) Copy
http://lamp.icsi.berkeley.edu/lamp/
A software package for the inference of locus-specific ancestry in recently admixed populations. LAMP-LD takes the genotypes of admixed individuals as well as reference haplotype panels approximating the mixing ancestral populations, and outputs the estimated number of alleles from each ancestry in each locus for each individual. The LAMP-LD package also includes the program LAMP-HAP, which processes haplotype data when high-quality phasing is available, and utilizes trio nuclear family designs to improve estimation accuracy. LAMP-LD is based on a window-based processing combined within a hierarchical Hidden Markov Model. It can process 2,3 or 5 mixing populations, and its short per-sample processing time makes it suitable for analyzing large datasets of dense SNP panels. The original program LAMP does not use the LD and therefore is not as accurate, but it is useful in cases where the SNP density is not high enough or when the ancestral haplotypes are unkown.
Proper citation: Local Ancestry in adMixed Populations (RRID:SCR_001258) Copy
http://sourceforge.net/projects/ngsrich/
Software for target enrichment performance for next-generation sequencing.
Proper citation: NGSrich (RRID:SCR_001333) Copy
https://www.bioconductor.org/packages//2.10/bioc/html/oneChannelGUI.html
Software library that provides a graphical interface for microarray gene and exon level analysis as well as miRNA/mRNA-seq data analysis. The package was developed to simplify the use of Bioconductor tools for beginners having limited or no experience in writing R code.
Proper citation: oneChannelGUI (RRID:SCR_001325) Copy
http://itb.biologie.hu-berlin.de/~futschik/software/R/cycle/index.html
Software package for the identification of periodically expressed genes using Fourier analysis and the statistical assessment of significance using different background models.
Proper citation: CYCLE (RRID:SCR_001328) Copy
https://www.bioconductor.org/packages//2.12/bioc/html/LMGene.html
Software package for Data Transformation and Identification of Differentially Expressed Genes in Gene Expression Arrays.
Proper citation: LMGene (RRID:SCR_001329) Copy
http://bioinf.wehi.edu.au/affylmGUI/
R software package providing a Graphical User Interface for analysis of Affymetrix microarray data, using the limma package (Linear Models for MicroArray data). While not as powerful as limma to the expert user, it offers a simple point-and-click interface to many of the commonly-used limma and affy functions. You need to have R 1.9.0 or later, Tcl/Tk 8.3 or later (ActiveTcl for Windows, Tcl/Tk Source for Linux/Unix, or X11 Tcl/Tk for MacOSX) and the limma, affylmGUI, and tkrplot R packages. It has been succesfully tested on Windows 2000, Windows XP, RedHat/Fedora Linux, and on Mac OSX with X11.
Proper citation: affylmGUI (RRID:SCR_001320) Copy
http://www.bioconductor.org/packages/release/bioc/html/arrayQuality.html
Software functions for performing print-run and array level quality assessment.
Proper citation: arrayQuality (RRID:SCR_001315) Copy
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