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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
DOSY Toolbox
 
Resource Report
Resource Website
DOSY Toolbox (RRID:SCR_002409) software resource Software toolbox for processing PFG NMR diffusion data that aims to incorporate many of the important processing schemes. It has a graphical user interface to make it easy to access a variety of different processing schemes (and a command mode for more advanced options). It is written in MATLAB, but can also be obtained as free standing compiled version that does not require a MATLAB installation. The MATLAB version runs on any platform, and the compiled version is presently available for Windows, Linux, and Mac. diffusion-ordered spectroscopy, matlab, mac os x, unix/linux, windows is listed by: OMICtools
has parent organization: University of Manchester; Manchester; United Kingdom
PMID:19666235 Free, Available for download, Freely available OMICS_03393 SCR_002409 The DOSY Toolbox processing PFG-NMR diffusion data, The DOSY Toolbox 2026-09-12 12:55:40 0
QDNAseq
 
Resource Report
Resource Website
100+ mentions
QDNAseq (RRID:SCR_003174) software resource Software package for quantitative DNA sequencing for chromosomal aberrations providing a robust, cost-effective WGS method for DNA copy number analysis. The genome is divided into non-overlapping fixed-sized bins, number of sequence reads in each counted, adjusted with a simultaneous two-dimensional loess correction for sequence mappability and GC content, and filtered to remove spurious regions in the genome. Downstream steps of segmentation and calling are also implemented via packages DNAcopy and CGHcall, respectively. software package, unix/linux, mac os x, windows, r, copy number variation, dna-seq, genetics, genome annotation, preprocessing, quality control, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:25236618 Free, Available for download, Freely available OMICS_05902, biotools:qdnaseq https://github.com/ccagc/QDNAseq, https://bio.tools/qdnaseq SCR_003174 QDNAseq - Quantitative DNA sequencing for chromosomal aberrations 2026-09-12 12:55:53 168
ABS filter
 
Resource Report
Resource Website
ABS filter (RRID:SCR_005328) ABS filter software resource R package for identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data. unix/linux is listed by: OMICtools
has parent organization: Ecole Polytechnique Federale de Lausanne; Lausanne; Switzerland
PMID:24255646 GNU General Public License, v3 OMICS_00427 SCR_005328 R package - ABS filter, absfilter 2026-09-12 12:56:24 0
TagDust
 
Resource Report
Resource Website
50+ mentions
TagDust (RRID:SCR_004175) TagDust software resource A program to eliminate artifactual reads from next-generation sequencing data sets. unix/linux, bio.tools, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:19737799 biotools:tagdust, OMICS_01095, biotools:nexalign https://bio.tools/tagdust, https://bio.tools/nexalign SCR_004175 2026-09-12 12:56:10 55
Kdetrees
 
Resource Report
Resource Website
Kdetrees (RRID:SCR_004522) software resource R package using a non-parametric method for estimating distributions of phylogenetic trees, with the goal of identifying trees that are significantly different from the rest of the trees in the sample. applet, mac os x, unix/linux, windows, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: CRAN
PMID:24764459 GNU General Public License, v2 biotools:kdetrees, OMICS_04172 https://github.com/grady/kdetrees, https://bio.tools/kdetrees SCR_004522 kdetrees: Nonparametric method for identifying discordant phylogenetic trees 2026-09-12 12:56:14 0
aLFQ
 
Resource Report
Resource Website
10+ mentions
aLFQ (RRID:SCR_005925) software resource An R-package for estimating absolute protein quantities from label-free liquid chromatography tandem mass spectrometry (LC-MS/MS) proteomics data. It supports the commonly used absolute label-free protein abundance estimation methods (TopN, iBAQ, APEX, NSAF and SCAMPI) for LC-MS/MS proteomics data, quantifying on either MS1-, MS2-levels or spectral counts together with validation algorithms to enable automated data analysis and error estimation. Specifically, they used Monte-carlo cross-validation and bootstrapping for model selection and imputation of proteome-wide absolute protein quantity estimation. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
PMID:24753486 GNU General Public License, v3 or greater OMICS_04053 SCR_005925 aLFQ: An R-package for estimating absolute protein quantities from label-free LC-MS/MS proteomics data 2026-09-12 12:56:33 22
YuGene
 
Resource Report
Resource Website
10+ mentions
YuGene (RRID:SCR_006023) software resource Software providing a simple method for comparison of gene expression generated across different experiments, and on different platforms; that does not require global renormalization, and is not restricted to comparison of identical probes. YuGene works on a range of microarray dataset distributions, such as between manufacturers. The resulting output allows direct comparisons of gene expression between experiments and experimental platforms. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
PMID:24667244 GNU General Public License, v2, v3 OMICS_04030 SCR_006023 YuGene: A simple approach to scale gene expression data derived from different platforms for integrated analyses 2026-09-12 12:56:34 16
RUVSeq
 
Resource Report
Resource Website
100+ mentions
RUVSeq (RRID:SCR_006263) software resource Software package that implements the remove unwanted variation (RUV) methods for the normalization of RNA-Seq read counts between samples. software package, unix/linux, mac os x, windows, r, differential expression, preprocessing, rna-seq is listed by: OMICtools
has parent organization: Bioconductor
PMID:25150836 Artistic License, v2 OMICS_05652 SCR_006263 RUVSeq: Remove Unwanted Variation from RNA-Seq Data 2026-09-12 12:56:37 481
CAMERA - Collection of annotation related methods for mass spectrometry data
 
Resource Report
Resource Website
1+ mentions
CAMERA - Collection of annotation related methods for mass spectrometry data (RRID:SCR_002466) CAMERA software resource A Bioconductor package integrating algorithms to extract compound spectra, annotate isotope and adduct peaks, and propose the accurate compound mass even in highly complex data. standalone software, mac os x, unix/linux, windows, r, spectra, extraction, annotation, liquid chromatography, mass spectrometry, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:22111785 Free, Available for download, Freely available biotools:camera, OMICS_03366 https://bio.tools/camera SCR_002466 CAMERA - Collection of annotation related methods for mass spectrometry data 2026-09-12 12:55:41 4
Iterative Signature Algorithm
 
Resource Report
Resource Website
Iterative Signature Algorithm (RRID:SCR_002327) isa2, ISA software resource A biclustering algorithm that finds modules in an input matrix. A module or bicluster is a block of the reordered input matrix. standalone software, mac os x, unix/linux, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: CRAN
PMID:12689096 Creative Commons Attribution-NonCommercial-ShareAlike License, v3 biotools:isa, OMICS_03487 https://bio.tools/isa SCR_002327 isa2: The Iterative Signature Algorithm 2026-09-12 12:55:39 0
ExomeDepth
 
Resource Report
Resource Website
100+ mentions
ExomeDepth (RRID:SCR_002663) software resource Software that calls copy number variants (CNVs) from targeted sequence data, typically exome sequencing experiments designed to identify the genetic basis of Mendelian disorders. software package, unix/linux, mac os x, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: CRAN
PMID:22942019 Free, Available for download, Freely available OMICS_05443, biotools:exomedepth https://bio.tools/exomedepth SCR_002663 2026-09-12 12:55:44 295
MethylAid
 
Resource Report
Resource Website
50+ mentions
MethylAid (RRID:SCR_002659) software resource Software for visual and interactive quality control of large Illumina 450k data sets. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored. software package, illumina, mac os x, unix/linux, windows, r, dna methylation, gui, methylation array, microarray, quality control, two channel, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:25147358 Free, Available for download, Freely available biotools:methylaid, OMICS_05457 http://www.bioconductor.org/packages/release/bioc/html/MethylAid.html, http://shiny.bioexp.nl/MethylAid/, https://bio.tools/methylaid SCR_002659 MethylAid - Visual and interactive quality control of large Illumina 450k data sets, MethylAid: Visual and interactive quality control of large Illumina 450k data sets 2026-09-12 12:55:44 68
AliView
 
Resource Report
Resource Website
1000+ mentions
AliView (RRID:SCR_002780) software resource Software for aligning viewing and editing dna / aminiacid sequences, intuitive, fast and leightweight. It has been designed to meet the requirements of next generation sequencing era phylogenetic datasets. unix/linux, mac os x, windows, java is listed by: OMICtools PMID:25095880 Free, Freely available OMICS_05209 http://www.ormbunkar.se/aliview/ SCR_002780 2026-09-12 12:55:46 1039
NetPathMiner
 
Resource Report
Resource Website
1+ mentions
NetPathMiner (RRID:SCR_002757) software resource Software that implements a flexible module-based process flow for network path mining and visualization, which can be fully inte-grated with user-customized functions. It supports construction of various types of genome scale networks from three different pathway file formats (KGML, SBML and BioPAX), enabling its utility to most common pathway databases. In addition, it provides different visualization techniques to facilitate the analysis of even thousands of output paths. software package, mac os x, unix/linux, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:25075120 Free, Freely available, Available for download biotools:netpathminer, OMICS_05210 https://bio.tools/netpathminer SCR_002757 NetPathMiner: R package for network path mining through gene expression 2026-09-12 12:55:46 3
CGHnormaliter
 
Resource Report
Resource Website
1+ mentions
CGHnormaliter (RRID:SCR_002936) software resource Software for normalization and centralization of array comparative genomic hybridization (aCGH) data with imbalanced aberrations. The algorithm uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs). standalone software, mac os x, unix/linux, windows, r, array comparative genomic hybridization, copy number alteration, microarray, preprocessing is listed by: OMICtools
has parent organization: Bioconductor
PMID:20418341 Free, Available for download, Freely available OMICS_02572 http://www.bioconductor.org/packages/release/bioc/html/CGHnormaliter.html SCR_002936 CGHnormaliter - Normalization of array CGH data with imbalanced aberrations. 2026-09-12 12:55:49 2
Chimera
 
Resource Report
Resource Website
100+ mentions
Chimera (RRID:SCR_002959) software resource A Bioconductor package that organizes, annotates, analyses and validates fusions reported by different fusion detection tools. The current implementation can deal with output from bellerophontes, chimeraScan, deFuse, fusionCatcher, FusionFinder, FusionHunter, FusionMap, mapSplice, Rsubread, tophat-fusion, tophat-fusion-post and STAR. The core of Chimera is a fusion data structure that can store fusion events detected with any of the aforementioned tools. software package, unix/linux, mac os x, windows, r, infrastructure is listed by: OMICtools
is listed by: SoftCite
has parent organization: Bioconductor
PMID:25286921 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_06335 SCR_002959 chimera - A package for secondary analysis of fusion products 2026-09-12 12:55:49 419
Triplex
 
Resource Report
Resource Website
10+ mentions
Triplex (RRID:SCR_003061) software resource Software package that provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many canonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D. software package, mac os x, unix/linux, windows, r, gene regulation, sequence matching, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23709494 Free, Available for download, Freely available OMICS_06259, biotools:triplex http://www.fi.muni.cz/~lexa/triplex/, https://bio.tools/triplex SCR_003061 triplex - Search and visualize intramolecular triplex-forming sequences in DNA 2026-09-12 12:55:51 10
bwtool
 
Resource Report
Resource Website
10+ mentions
bwtool (RRID:SCR_003035) software resource A command-line utility for bigWig files designed to read bigWig files rapidly and efficiently, providing functionality for extracting data and summarizing it in several ways, globally or at specific regions. Its functionality is subdivided into subprograms that roughly fall into three categories: data extraction, analysis, and data modification, although e.g. in the case of the matrix program or the sax program, the boundary between data extraction and analysis isn't very strong. The data modification programs all have the behavior that a bigWig is inputted and a new bigWig is outputted. standalone software, unix/linux, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:2448936 Free, Available for download, Freely available biotools:bwtool, OMICS_05125 https://bio.tools/bwtool SCR_003035 2026-09-12 12:55:50 22
enviPat
 
Resource Report
Resource Website
10+ mentions
enviPat (RRID:SCR_003034) software resource Software for fast and very memory-efficient calculation of isotope patterns, subsequent convolution to theoretical envelopes (profiles) plus valley detection and centroidization or intensoid calculation. Batch processing, resolution interpolation, wrapper, adduct calculations and molecular formula parsing. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
Free, Freely available OMICS_02408 SCR_003034 enviPat: Isotope pattern profile and centroid calculation for mass spectrometry 2026-09-12 12:55:50 33
MoSDi
 
Resource Report
Resource Website
1+ mentions
MoSDi (RRID:SCR_003037) data analysis software, data processing software, software application, software resource, software toolkit Sequence analysis toolkit that contains a lot of sequence analysis algorithms, including methods for 1) motif statistics, e.g. compute the exact occurrence count distribution of a motif, 2) exact motif discovery: extraction of motifs with provably optimal p-value, 3) analysis of pattern matching algorithms: compute (for given algorithm and pattern) the exact distribution of the number of character accesses caused by searching a random text, 4) statistics of fragment masses resulting from proteolytic cleavage of proteins, 5) computing the expectated read length of sequencing reads for a given dispensation order (for 454 or IonTorrent) and 6) analysing sensitivity of spaced alignment seeds. standalone software, unix/linux, motif is listed by: OMICtools
has parent organization: Google Code
PMID:19478010 Free, Freely available OMICS_06271 https://bio.tools/mosdi SCR_003037 Motif Statistics and Discovery, Motif Statistics and Discovery - Sequence analysis toolkit for bioinformatics 2026-09-12 12:55:50 2

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