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https://flowcytometrycore.vai.org/

Core provides cell analysis and sorting services. Instruments include Cytek Aurora, Beckman Coulter CytoFLEX S, Thermo Fisher Attune CytPix, SONY MA900, and BD FACSSymphony S6.

Proper citation: Van Andel Institute Flow Cytometry Core Facility (RRID:SCR_022685) Copy   

•   Source: SciCrunch Registry

https://drexel.edu/core-facilities/facilities/material-characterization/

Facility provides technical expertise and instrumentation including nanoscience and engineering, polymer research, biomedical engineering, and chemistry and physics of solid materials.Houses electron microscopes, X-ray diffractometers, X-ray photoelectron spectrometer and suite of sample preparation tools. Staff members provide expert consultation, training and assistance to MCC users. Core is involved in teaching both undergraduate and graduate level courses in Materials Science and Engineering, Mechanical Engineering and Mechanics, Biomedical Engineering, and Biology. Trained and certified users are welcome to work independently on our instruments.

Proper citation: Drexel University Materials Characterization Core Facility (RRID:SCR_022684) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/physiology/research/echo-facility.html

Preclinical ultrasound imaging. Provided instruments include Vevo 3100, Vevo 3100 LAZR-X, Perkin Elmer Vega.

Proper citation: University of Nebraska Medical Center Echocardiography Imaging Core Facility (RRID:SCR_022683) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/referral-center-for-animal-models

Core mission is to discover, create, characterize, treat, and share naturally occurring hereditary disorders in dogs and cats that are orthologous to those found in human patients.�Provides expertise in discovering, characterizing, and developing therapies for genetic disease in dogs and cats, which serve as models of same diseases that occur in children.�Specializes in molecular discovery of mutations, clinical phenotyping, biochemical and histological characterization, development of therapies which are translatable to human patients and preclinical trials in animal models of human disease.�

Proper citation: University of Pennsylvania Penn Vet Referral Center for Animal Models of Human Genetic Disease Core Facility (RRID:SCR_022440) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/centers-laboratories/center/center-for-host-microbial-interactions

Offers consultation and laboratory services for high-throughput sequencing (HTS) experiments, with particular expertise and interest in microbiome/metagenome and RNA-seq applications. Provides instrumentation, including Illumina NextSeq 2000 and single cell platforms from 10X genomics and 1CellBio. Offers full service options, as well as hands on instruction for trainees who want to learn best practices for wet lab aspects of genomics experiments. Offers consultation services for all phases of HTS studies, from study design to bioinformatics analysis.

Proper citation: University of Pennsylvania Penn Vet Center for Host Microbial Interactions Core Facility (RRID:SCR_022434) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/r/rips/research/pharmacy

Our Investigational Pharmacy team is responsible for dispensing both inpatient and outpatient investigational medication for industry-sponsored, grant-funded and investigator-initiated protocols. We provide pharmacy services customized to each research protocol conducted at Cincinnati Children�s.

Proper citation: Cincinnati Children's Hospital Investigational Pharmacy Core Facility (RRID:SCR_022650) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/meg

Core facilitates study of normal and pathologic brain processes using magnetoencephalography.The purpose of the core is to make magnetoencephalography available to researchers across the institute.

Proper citation: Cincinnati Children's Hospital Magnetoencephalography Core Facility (RRID:SCR_022648) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dev-biology/core

Offers comprehensive CRISPR services to generate gene edited rodents and cells, and helps generate transgenic and chimeric mice via our microinjection service, cryopreserving unique mouse lines, and recovering them from liquid nitrogen storage via IVF and embryo transfer services.

Proper citation: Cincinnati Children's Hospital Transgenic Animal and Genome Editing Core Facility (RRID:SCR_022642) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/neuronsrus/

Core supplies suspensions of neuronal cells prepared from rodent brain for various downstream applications, including primary cell culture. Supplies rat or mouse cells isolated from cortex or hippocampus either in suspension or plates. Custom dissection services are available for other brain regions or for user supplied genetically modified mice.

Proper citation: University of Pennsylvania Perelman School of Medicine Neurons R Us Core Facility (RRID:SCR_022421) Copy   

•   Source: SciCrunch Registry

https://www.themiamiproject.org/research-resources/core-facilities/drug-discovery-core/

Core at Miami Project to Cure Paralysis leverages PerkinElmer Opera Phenix Plus high content screening system to provide assay development and phenotypic screening. Facility is also equipped with PerkinElmer Janus G3 liquid handler, featuring modular and variable dispense heads, to automate screening workflows and enhance throughput. Core supports phenotypic and target-based assays. Phenotypic assays range from 2D to 3D, widefield to confocal, and antibody to dye based. It collaborates with users to develop customized assays and analytical pipelines tailored to their specific needs. Current specializations include neurite tracing, lipid droplet quantification, cell viability, morphological and kinetic analyses, phagocytosis, cell marker detection, cell adhesion, among others.

Proper citation: Drug Discovery Core Facility (RRID:SCR_022542) Copy   

•   Source: SciCrunch Registry

http://agl.tamu.edu/

Assists graduate students, staff and faculty launch, economize and expedite their research, especially when it involves DNA extraction and quality checks, targeted genotyping and DNA content analysis. Facilitates usage of complementary cores and assists with research planning and data analysis.AGL members have free lab access and reduced costs for services as well as one-on-one training and advising with AGL staff.

Proper citation: Texas A and M University AgriGenomics Laboratory Core Facility (RRID:SCR_022533) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/transcriptional-regulation-expression-facility-trex

Facility offers genomics profiling services including RNAseq, small RNA sequencing, and ATACseq.

Proper citation: Cornell University Biotechnology Resource Center Transcriptional Regulation and Expression Core Facility (RRID:SCR_022532) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/single-cell-genomics

Core to perform expression level analysis of thousands of genes in parallel.Uses RNA-Seq assays from Tecan Genomics, Takara and Illumina for samples with limited amounts of starting RNA. Microarray technology utilizing the Affymetrix GeneChip platform is also available.

Proper citation: Cincinnati Children's Hospital Single Cell Genomics Core Facility (RRID:SCR_022653) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/cardio-imaging

Offers imaging techniques using imaging and measurement tools. Offers consulting services ranging from educational seminars to assistance with grant and industry funding support.

Proper citation: Cincinnati Children's Hospital Cardiovascular Imaging Core Facility (RRID:SCR_022626) Copy   

•   Source: SciCrunch Registry

http://www.sylvester.org/OGSR

Provides access to technologies and services for study of genomics and epigenomics of cancer, in addition to providing technical expertise for project design, trouble shooting and pre and post award support. Services include next generation sequencing, single cell genomics, spatial genomics, gene expression assays and molecular quantitation, services for sample extraction and QC.

Proper citation: University of Miami Sylvester Onco Genomics Shared Resource Core Facility (RRID:SCR_022502) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/b/bmi/resource-service

Provides computational resources, services, and support to investigators including clinical research informatics, application and technology development, and bioinformatics analyses.

Proper citation: Cincinnati Children's Hospital Biomedical Informatics Core Facility (RRID:SCR_022622) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/genomics/about/

Full service sequencing facility to assist with genetic and genomic research. Part of Integrated Genomics Cores. Offers comprehensive library services, NextGen sequencing and alternative technologies including long reads. Offers library preparations and multiple sequencing platforms including MiSeq, HiSeq, NovaSeq, NextSeq, BioNano, Oxford Nanopore. Services also include using techniques and data analyses via sister core BARC.

Proper citation: UNC School of Medicine Integrated Genomics Cores High Throughput Sequencing Core Facility (RRID:SCR_022620) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/c/critical/medialab

Develops high quality video and animation to enhance medical education.

Proper citation: Cincinnati Children's Hospital Critical Care Media Lab Core Facility (RRID:SCR_022629) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/radcore

Clinical Imaging Core Service Center includes RADCORE, Tumor Response Assessment (TRAC) and Research imaging guided biopsies cores. Supports cancer clinical trials. RADCORE staff include clinical research professionals with range of expertise in imaging based clinical research protocols and offers services in consultation, management of research protocols and Radiology IND/IDE support office. Tumor Response Assessment Core (TRAC) team of Radiologist is skilled in evaluating tumor response imaging assessments for patients enrolled in cancer clinical trials being conducted at UPHS. Research imaging guided biopsies Interventional Radiology and technical staff provides consultation to define biopsy protocol and pathology tissue collection.

Proper citation: University of Pennsylvania Perelman School of Medicine Clinical Imaging Service Center Core Facility (RRID:SCR_022487) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/viral-vector-core

Provides research grade retroviral, lentiviral and adeno associated virus vectors. Offers generation of stable producer lines, and non-GMP quality control testing including vector titer by functional assay FACS or PCR, endotoxin, mycoplasma, and USP sterility testing.Provides standard packaging plasmids, the investigator provides the viral vector to be used for the production run.

Proper citation: Cincinnati Children's Hospital Viral Vector Core Facility (RRID:SCR_022641) Copy   

•   Source: SciCrunch Registry