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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.clinicbiobanc.org/en_index.html
A biobank of repositories which works to obtain, store, manage and distribute large collections of human biological samples of phenotypes and diseases of marked interest for researchers. The biobank sample collection is made up of three extensive repositories. The Neurological Tissue Biobank is a nervous tissue repository (brain and spinal cord) created from donations from cadavers with or without neurological conditions. It helps facilitate research in neurological illnesses. The Tumour Biobank and Anatomical Pathologies Collections is a repository of tumorous tissue and samples from cancer patients. The Blood and Fluid Biobank is a repository which contains samples of metabolic, inflammatory bowel, hepatic, digestive and maternal and foetal diseases, among others. It houses a large range of samples of scientific interest, primarily DNA, serum and plasma.
Proper citation: Biobank of Hospital Clinic - IDIBAPS (RRID:SCR_004530) Copy
http://www.med.umich.edu/mgpc/cores/vivo.htm
Core facility that consists of the following 4 distinct programs: In Vivo Small Animal Studies Program, Organoid/Enteroid Modeling Program, Biospecimens Banking Service, and Clinical Design and Statistics.
Proper citation: University of Michigan Center for Gastrointestinal Research In Vivo Animal and Human Studies Core (RRID:SCR_015608) Copy
http://www.uchicagoddrcc.org/research-cores/tissue-and-cell-analysis-core
Core whose services include anatomic pathology review of human and experimental animal tissues as well as consultation in the best approaches for such analyses, cost-effective and high quality processing and staining of formalin-fixed paraffin-embedded tissues, and making collections of human tissue and imaging technologies available to researchers.
Proper citation: University of Chicago Digestive Diseases Research Core Center Tissue and Cell Imaging Core (RRID:SCR_015607) Copy
https://ww2.mc.vanderbilt.edu/ddrc/
Center whose objectives include promoting digestive diseases-related research in an integrative, collaborative and multidisciplinary manner, developing and implementing programs for attracting, training, and retaining young investigators in digestive disease-related research, and facilitating the transfer of basic research discoveries to improvements in prevention and/or clinical care.
Proper citation: Vanderbilt Digestive Disease Research Center (RRID:SCR_015225) Copy
https://www.bcm.edu/research/centers/digestive-disease
Center designed to serve basic and clinical scientists at institutions within the Texas Medical Center, including Baylor College of Medicine, The University of Texas Health Science Center at Houston and the MD Anderson Cancer Center. It facilitates digestive diseases research, promotes translational collaborative research between basic and clinical areas, develops new projects, nurtures new investigators, and provides GI educational activities.
Proper citation: Texas Medical Center Digestive Diseases Center (RRID:SCR_015191) Copy
https://www.cincinnatichildrens.org/research/divisions/d/dhc
Center that is located within Cincinnati Children's Hospital Medical Center, that serves as a University of Cincinnati Academic Health Center resource to foster pediatric digestive disease research and make discoveries to restore digestive health.
Proper citation: Cincinnati Digestive Health Center (RRID:SCR_015196) Copy
https://www.niddk.nih.gov/research-funding/research-programs/digestive-disease-centers
Center of collaborating research centers working on the research of digestive and liver-related diseases. Each center focuses on etiology, treatment, and prevention of digestive and/or liver diseases.
Proper citation: Digestive Disease Centers (RRID:SCR_015212) Copy
https://case.edu/medicine/cddrcc/
Center that is focused on what produces the digestive diseases that affect millions of people in the U.S., such as inflammatory bowel disease, hepatitis, metabolic syndromes and obesity.
Proper citation: Cleveland Digestive Diseases Research Core Center (RRID:SCR_015210) Copy
Research center whose purpose is to advance research in digestive disease with a focus on interactions between host and environment. It provides research resources to basic and translational investigators through various core facilities.
Proper citation: Washington University Digestive Diseases Research Core Center (RRID:SCR_015252) Copy
http://www.med.upenn.edu/molecular/
Center that aims to unite investigators with interests in digestive, liver and pancreatic physiology and disease in the exploration of creative experimental approaches. The scientific focus of the Center revolves around the molecular controls of cellular growth and differentiation in the digestive tract, liver and pancreas with the goal of achieving a new level of integration in biology, pathobiology, and therapy.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases (RRID:SCR_015617) Copy
Center that aims to advance basic science and translational digestive diseases research at the Johns Hopkins University School of Medicine. Its goal is to improve the health of patients with the broad spectrum of gastrointestinal and hepatic disorders.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center (RRID:SCR_015589) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/translationalResearchEnhancementCore.html
Core facility whose services include establishing Best Practices (BP) and uniform Standard Operating Procedures (SOPs) for the collection, annotation, processing, storage, management, distribution, and ethical use of human specimens, and to provide access to specimens by investigators as well as patient identification, patient recruitment, facilitation of patient trials, translational research and basic research through creation of a patient registry and database.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Translational Research Enhancement Core (RRID:SCR_015594) Copy
Center at UNC Chapel Hill and North Carolina State University for collaborative GI research. Its mission is to promote and enhance multidisciplinary digestive disease research.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease (RRID:SCR_015612) Copy
Communication network of current and potential biomedical research investigators and technical personnel from traditionally under-served communities: African American, Hispanic American, American Indian, Alaskan Native, Native Hawaiian, and other Pacific Islanders. The major objective of the network is to encourage and facilitate participation of members of underrepresented racial and ethnic minority groups in the conduct of biomedical research in the fields of diabetes, endocrinology, metabolism, digestive diseases, nutrition, kidney, urologic and hematologic diseases. A second objective is to encourage and enhance the potential of the underrepresented minority investigators in choosing a biomedical research career in these fields. An important component of this network is promotion of two-way communications between network members and the NIDDK.
Proper citation: Network of Minority Health Research Investigators (RRID:SCR_006589) Copy
https://ddrcc.wustl.edu/scientific-cores/biobank-core/
Core facility that collects and provides specimens and longitudinal clinical data from patients with digestive diseases. Specimens collected and processed by the core currently include blood, surgical resections, endoscopic biopsies, and stool. Clinical information is stored in a database and linked to specimens and data obtained from these specimens.
Proper citation: Washington University Digestive Diseases Research Core Center Biobank Core (RRID:SCR_015256) Copy
https://ddrcc.wustl.edu/scientific-cores/administrative-resource-access-core/
Core facility which provides DDRCC members facilitated access to technology and assistance for genetic profiling of clinical and experimental samples.
Proper citation: Washington University Digestive Diseases Research Core Center Administrative and Resource Access Core (RRID:SCR_015253) Copy
https://ddrcc.wustl.edu/scientific-cores/advanced-imaging-tissue-analysis-core/
Core facility which provides comprehensive histologic and immunohistochemical support, advanced microscopic imaging and image analysis services to digestive disease researchers. The Tissue Analysis Component performs animal and human tissue embedding, sectioning, routine and special staining, and immunohistochemical analyses, and provides training in all services while the Advanced Image Analysis Component provides access to and training in routine light, fluorescent and inverted fluorescent microscopy and quantitative image analysis.
Proper citation: Washington University Digestive Diseases Research Core Center Advanced Imaging and Tissue Analysis Core (RRID:SCR_015254) Copy
http://www.med.unc.edu/cgibd/cores/advanced-analytics
Core facility provides solutions for studying proteins, peptides, and other molecules, including mRNA and cDNA. The Core's immunotechnologies (IT) component provides consultation, ordering, and immunoassay services, and supports a variety of analytes in both traditional ELISA/EIA and xMAP-based multiplex bead assay formats.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Advanced Analytics Core (RRID:SCR_015613) Copy
http://www.med.unc.edu/cgibd/cores/large-animal-core
Core facility that provides consultation and procedural expertise on development on novel models of relevant digestive diseases in large animals.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Large Animal Models Core (RRID:SCR_015619) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/proteomicsCore.html
Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Proteomics Core (RRID:SCR_015597) Copy
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