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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Mouse Genome Database
 
Resource Report
Resource Website
500+ mentions
Mouse Genome Database (RRID:SCR_012953) MGD data or information resource, database Community model organism database for laboratory mouse and authoritative source for phenotype and functional annotations of mouse genes. MGD includes complete catalog of mouse genes and genome features with integrated access to genetic, genomic and phenotypic information, all serving to further the use of the mouse as a model system for studying human biology and disease. MGD is a major component of the Mouse Genome Informatics.Contains standardized descriptions of mouse phenotypes, associations between mouse models and human genetic diseases, extensive integration of DNA and protein sequence data, normalized representation of genome and genome variant information. Data are obtained and integrated via manual curation of the biomedical literature, direct contributions from individual investigators and downloads from major informatics resource centers. MGD collaborates with the bioinformatics community on the development and use of biomedical ontologies such as the Gene Ontology (GO) and the Mammalian Phenotype (MP) Ontology. gene, genome, genetic, chromosome, clone, cytogenetic, dna, genomic, inbred, mammalian, mouse, mutant, ortholog, phenotype, primer, protein, reagent, sequence, strain, bio.tools is used by: DisGeNET
is listed by: Debian
is listed by: bio.tools
is related to: Mouse Genome Informatics (MGI)
has parent organization: Jackson Laboratory
NHGRI HG000330 PMID:21051359 biotools:mgi, biotools:mgd, nif-0000-10301 http://www.informatics.jax.org/mgihome/projects/overview.shtml, https://bio.tools/mgd, https://bio.tools/mgi SCR_012953 Mouse Genome Informatics: Mouse Genome Database, MGID, Mouse Genome Informatics Database 2026-09-05 06:32:03 545
HOMD
 
Resource Report
Resource Website
100+ mentions
HOMD (RRID:SCR_012770) HOMD data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE.Documented on April 14,2022. Database of comprehensive information on the approximately 600 prokaryote species that are present in the human oral cavity. The majority of these species are uncultivated and unnamed, recognized primarily by their 16S rRNA sequences. The HOMD presents a provisional naming scheme for the currently unnamed species so that strain, clone, and probe data from any laboratory can be directly linked to a stably named reference entity. The HOMD links sequence data with phenotypic, phylogenetic, clinical, and bibliographic information. Full and partial oral bacterial genome sequences determined as part of this project and the Human Microbiome Project, are being added to the HOMD as they become available. HOMD offers easy to use tools for viewing all publicly available oral bacterial genomes. Data is also downloadable. taxon, genome, 16s rna, sequence, actinobacteria, bacteroidetes, chlamydiae, chloroflexi, euryarchaeota, firmicutes, fusobacteria, proteobacteria, spirochaetes, sr1, synergistetes, tenericutes, tm7, nomenclature, naming scheme, human, FASEB list has parent organization: Forsyth Institute NIDCR ;
ARRA ;
DOE contract U01 DE016937;
DOE DE016937;
DOE DE015847;
DOE DE017106
PMID:20624719
PMID:20656903
THIS RESOURCE IS NO LONGER IN SERVICE nlx_22198, r3d100012898 SCR_012770 Human Oral Microbiome Database 2026-09-05 06:32:02 137
SYFPEITHI: A Database for MHC Ligands and Peptide Motifs
 
Resource Report
Resource Website
100+ mentions
SYFPEITHI: A Database for MHC Ligands and Peptide Motifs (RRID:SCR_013182) SYFPEITHI data or information resource, database SYFPEITHI is a database comprising more than 7000 peptide sequences known to bind class I and class II MHC molecules. The entries are compiled from published reports only. It contains a collection of MHC class I and class II ligands and peptide motifs of humans and other species, such as apes, cattle, chicken, and mouse, for example, and is continuously updated. Searches for MHC alleles, MHC motifs, natural ligands, T-cell epitopes, source proteins/organisms and references are possible. Hyperlinks to the EMBL and PubMed databases are included. In addition, ligand predictions are available for a number of MHC allelic products. The database is based on previous publications on T-cell epitopes and MHC ligands. It contains information on: -Peptide sequences -anchor positions -MHC specificity -source proteins, source organisms -publication references Since the number of motifs continuously increases, it was necessary to set up a database which facilitates the search for peptides and allows the prediction of T-cell epitopes. The prediction is based on published motifs (pool sequencing, natural ligands) and takes into consideration the amino acids in the anchor and auxiliary anchor positions, as well as other frequent amino acids. The score is calculated according to the following rules: The amino acids of a certain peptide are given a specific value depending on whether they are anchor, auxiliary anchor or preferred residue. Ideal anchors will be given 10 points, unusual anchors 6-8 points, auxiliary anchors 4-6 and preferred residues 1-4 points. Amino acids that are regarded as having a negative effect on the binding ability are given values between -1 and -3. Sponsors: SYFPEITHI is supported by DFG-Sonderforschungsbereich 685 and theEuropean Union: EU BIOMED CT95-1627, BIOTECH CT95-0263, and EU QLQ-CT-1999-00713. epitope, allele, allelic, amino acid, ape, bind, cattle, chicken, class i, class ii, human, immunological database, ligand, mhc, molecule, motif, mouse, natural, organism, peptide, product, protein, sequence, specie, t-cell, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tubingen; Tubingen; Germany
nif-0000-21383, biotools:syfpeithi https://bio.tools/syfpeithi SCR_013182 SYFPEITHI 2026-09-05 06:32:04 269
Therapeutically Relevant Multiple Pathways Database
 
Resource Report
Resource Website
1+ mentions
Therapeutically Relevant Multiple Pathways Database (RRID:SCR_013471) data or information resource, database The Therapeutically Relevant Multiple Pathways Database is designed to provide information about such multiple pathways and related therapeutic targets described in the literatures, the targeted disease conditions, and the corresponding drugs/ligands directed at each of these targets. This database currently contains 11 entries of multiple pathways, 97 entries of individual pathways, 120 targets covering 72 disease conditions along with 120 sets of drugs directed at each of these targets. Each entry can be retrieved through multiple methods including multiple pathway name, individual pathway name and disease name. Additional information provided include protein name, synonyms, Swissprot AC number, species, gene name and location, protein sequence (AASEQ) and gene sequence (NTSEQ) as well as potential therapeutic implications while applicable. Cross-links to other databases are provided which include Genecard, GDB, Locuslink, NCBI, KEGG, OMIM, SwissProt to facilitate the access of more detailed information about various aspects of the particular target or non-target protein. Queries can be submitted by entering or selecting the required information in any one or combination of the fields in the form. User can specify full name or any part of the name in a text field, or choose one item from an selection field. Sponsors: TRMP is supported by the National University of Singapore. drug, gene, condition, disease, intermolecular interactions and signaling pathways databases, ligand, literature, location, pathway, protein, sequence, specie, target, therapeutic, therapy nif-0000-21402 SCR_013471 TRMP 2026-09-05 06:32:07 3
Manipulate and Display a DNA Sequence
 
Resource Report
Resource Website
Manipulate and Display a DNA Sequence (RRID:SCR_013470) Manipulate and Display a DNA Sequence analysis service resource, data analysis service, production service resource, service resource A software tool that allows users to input a DNA (or RNA) sequence and obtain its inverse, complement or inverse complement. The program can also be used to display a DNA sequence and its complement in double-stranded format. Functions after users paste a DNA sequence into the upper text box, then click the appropriate button to place a manipulated form of the sequence in the lower text box. dna sequence, dna, rna, sequence, inverse, complement, inverse complement, base number has parent organization: Colorado State University; Colorado; USA nif-0000-31779 SCR_013470 Manipulate Display a DNA Sequence 2026-09-05 06:32:07 0
Codon and Codon-Pair Usage Tables
 
Resource Report
Resource Website
1+ mentions
Codon and Codon-Pair Usage Tables (RRID:SCR_018504) CoCoPUTs data or information resource, database Database includes genomic codon-pair and dinucleotide statistics of all organisms with sequenced genome. Facilitates genetic variation analyses and recombinant gene design. Derived from all available GenBank and RefSeq data. Codon-pair, codon, nucleotide, gene, genomic codon pair, dinucleotide statistic, sequence, genetic variation, recombinant gene design, data is related to: GenBank
is related to: RefSeq
PMID:31029701 Free, Freely available SCR_018504 2026-09-05 06:32:16 6
Database of Antimicrobial Activity and Structure of Peptides
 
Resource Report
Resource Website
50+ mentions
Database of Antimicrobial Activity and Structure of Peptides (RRID:SCR_016600) DBAASP data or information resource, database Collection of manually curated data regarding structure and antimicrobial activity of natural and synthetic peptides. Provides the information and analytical resources to develop antimicrobial compounds with the high therapeutic index. data, collection, structure, antimicrobial, activity, natural, synthetic, peptide, sequence International Science and Technology Center ;
NIAID G2102;
Shota Rustaveli National Science Foundation FR397718014
PMID:26578581
PMID:27060142
Free, Freely available SCR_016600 DataBase of Antimicrobial Activity and Structure of Peptides, Database of Antimicrobial Activity and Structure of Peptides 2026-09-05 06:32:13 53
RegulomeDB
 
Resource Report
Resource Website
100+ mentions
RegulomeDB (RRID:SCR_017905) data or information resource, database, service resource Database that annotates SNPs with known and predicted regulatory elements in intergenic regions of H. sapiens genome. Known and predicted regulatory DNA elements include regions of DNAase hypersensitivity, binding sites of transcription factors, and promoter regions that have been biochemically characterized to regulation transcription. Source of these data include public datasets from GEO, ENCODE project, and published literature. Annotate, SNP, regulatory, DNA, element, intergenic, region, human, genome, sequence, DNAase, hypersensitivity, binding, site, transcription, factor, promoter, region, data, FASEB list Beta Cell Consortium ;
NHGRI U54 HG 004558
PMID:22955989 Free, Freely available SCR_017905 2026-09-05 06:32:15 161
DREME
 
Resource Report
Resource Website
10+ mentions
DREME (RRID:SCR_016860) analysis service resource, data analysis service, production service resource, service resource Software tool to discover short, ungapped motifs (recurring, fixed-length patterns) that are relatively enriched in sequences compared with shuffled sequences or control sequences (sample output from sequences). discover, short, ungapped, motif, sequence, compare, shuffled, control, sample, output, recurring, fixed, length, pattern, data is listed by: MEME Suite - Motif-based sequence analysis tools Free, Available for download, Freely avaialble SCR_016860 Discriminative Regular Expression Motif Elicitation, DREME 2026-09-05 06:32:14 23
seqNMF
 
Resource Report
Resource Website
1+ mentions
seqNMF (RRID:SCR_017068) data analysis software, data processing software, software application, software resource Software tool for unsupervised discovery of sequential structure. Used to detect sequences in neural data generated by internal behaviors, such as animal thinking or sleeping. Used for unsupervised discovery of temporal sequences in high dimensional datasets in neuroscience without reference to external markers. sequence, structure, high, dimention, dataset, neuroscience, repeated, sequential, pattern, data has parent organization: Massachusetts Institute of Technology; Massachusetts; USA; Department of Energy ;
Labor and Economic Growth Computational Science Graduate Fellowship ;
G Harold and Leila Y. Mathers Foundation ;
NIBIB T32 EB019940;
NIDCD R01 DC009183;
NIMH R25 MH062204;
NINDS U19 NS10 4648;
Simons Foundation Simons Collaboration for the Global Brain ;
U.S. Department of Defense NDSEG Fellowship program
PMID:30719973 Free, Available for download, Freely available SCR_017068 2026-09-05 06:28:18 6
rnaSPAdes
 
Resource Report
Resource Website
50+ mentions
rnaSPAdes (RRID:SCR_016992) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for assembling transcripts from RNA-Seq data. Explores surprising computational parallels between assembly of transcriptomes and single cell genomes. Suitable for all kind of organisms. Part of SPAdes package since version 3.9. assembling, transcript, RNA-Seq, data, single, cell, genome, analysis, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: SPAdes
is related to: rnaQUAST
Russian Science Foundation 14-50-00069 DOI:10.1101/420208 Free, Available for download, Freely available biotools:rnaSPAdes_autogenerated https://bio.tools/rnaSPAdes_autogenerated SCR_016992 2026-09-05 06:28:16 58
Clustal 2
 
Resource Report
Resource Website
1000+ mentions
Clustal 2 (RRID:SCR_017055) alignment software, data processing software, data visualization software, image analysis software, software application, software resource Software tool for nucleotide sequence alignment. Graphical version of multiple sequence alignment program for DNA and proteins. Windows interface for ClustalW multiple sequence alignment program. Provides integrated environment for performing multiple sequence and profile alignments and analyzing results. Available on Linux, Mac and Windows. graphical, multiple, sequence, alignment, DNA, protein is related to: Clustal W2
is related to: Clustal Omega
CNRS ;
EMBL ;
INSERM ;
Ministère de la Recherche et Technologie ;
Science Foundation Ireland
PMID:17846036
PMID:9396791
Free, Available for download, Freely available biotools:clustal2 http://www.clustal.org/download/clustalx_help.html, https://bio.tools/clustal2 SCR_017055 Clustalx, CLUSTAL_X, clustalx, clustal X, clustal2 2026-09-05 06:28:17 1535
Nuclear Hormone Receptor Scan
 
Resource Report
Resource Website
1+ mentions
Nuclear Hormone Receptor Scan (RRID:SCR_016975) NHR-scan analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web interface for computational prediction of nuclear hormone receptor binding sites in genomic sequences. Flexible Hidden Markov Model framework to allow for variable spacing and orientation of half sites. Allows for parameter modifications. prediction, nuclear, hormone, receptor, binding, site, genomic, sequence, parameter, modification, analysis is listed by: OMICtools Canadian Institutes of Health Research ;
Pharmacia Corporation to the Center for Genomics and Bioinformatics
PMID:15563547 Free, Available, Acknowledgement requested OMICS_14042 SCR_016975 NHR-scan, NHR Scan, NHRScan, Nuclear Hormoe Receptor Scan 2026-09-05 06:28:16 5
EMBOSSMatcher
 
Resource Report
Resource Website
10+ mentions
EMBOSSMatcher (RRID:SCR_017252) alignment software, data access protocol, data processing software, image analysis software, software application, software resource, web service Software tool for pairwise sequence alignment. Identifies local similarities in two input sequences. One of EMBL-EBI search and sequence analysis tools. pairwise, sequence, alignment, identify, local, similarity, two, input, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
EMBL PMID:30976793 Free, Freely available biotools:ebi_search https://bio.tools/ebi_search SCR_017252 EMBOSS Matcher, emboss_matcher, EMBOSS_Matcher 2026-09-05 06:28:21 16
Juicer
 
Resource Report
Resource Website
100+ mentions
Juicer (RRID:SCR_017226) data analysis software, data processing software, software application, software resource Software platform for analyzing kilobase resolution Hi-C data. Open source tool for analyzing terabase scale Hi-C datasets. Allowes to transform raw sequence data into normalized contact maps. analysis, kilobase, resolution, Hi-C, data, terabase, dataset, transform, raw, sequence, normalized, contact, map has parent organization: Baylor College of Medicine; Houston; Texas Cancer Prevention Research Institute of Texas ;
Google Research Award ;
IBM University Challenge Award ;
McNair Medical Institute Scholar Award ;
NHGRI HG003067;
NHGRI HG006193;
NHLBI U01 HL130010;
NIH Office of the Director DP2 OD008540;
NSF PHY-1427654;
NVIDIA Research Center Award ;
PD Soros Fellowship ;
President Early Career Award in Science and Engineering ;
Welch Foundation
PMID:27467249 Free, Available for download, Freely available SCR_017226 2026-09-05 06:28:20 119
PIRATE
 
Resource Report
Resource Website
10+ mentions
PIRATE (RRID:SCR_017265) data analysis software, data processing software, software application, software resource Software pangenomics toolbox for clustering diverged orthologues in bacteria. Used to identify and classify orthologous gene families in bacterial pangenomes over wide range of sequence similarity thresholds. Pangenome, clustering, genomics, bacteria, orthologue, gene, sequence, amino acid, nucleotide, dataset, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/598391 Free, Available for download, Freely available biotools:PIRAtE https://bio.tools/PIRATE SCR_017265 Pangenome Iterative Refinement And Threshold Evaluation 2026-09-05 06:28:21 23
RepeatFiller
 
Resource Report
Resource Website
10+ mentions
RepeatFiller (RRID:SCR_017414) alignment software, data processing software, image analysis software, software application, software resource Software tool to incorporate newly detected repeat overlapping alignments into pairwise alignment chains. It only aligns local genomic regions that are bounded by colinear aligning blocks, as provided in chains, which makes it feasible to consider all seeds including those that overlap repetitive regions. Used to improve genome alignments by incorporating previously undetected local alignments between repetitive sequences. Repeat, overlapping, alignment, pairwise, chain, local, genomic, region, colinear, block, sequence, undetected, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Max Planck Institute of Molecular Cell Biology and Genetics; Dresden; Germany
DOI:10.1101/696922 Free, Freely available biotools:RepeatFiller, BioTools:RepeatFiller https://bio.tools/RepeatFiller, https://bio.tools/RepeatFiller, https://bio.tools/RepeatFiller SCR_017414 2026-09-05 06:28:24 16
trimAl
 
Resource Report
Resource Website
500+ mentions
trimAl (RRID:SCR_017334) data analysis software, data processing software, software application, software resource Software tool for automated removal of spurious sequences or poorly aligned regions from multiple sequence alignment. Software package for automated alignment trimming in large scale phylogenetic analyses. removal, spurious, sequence, poorly, aligned, region, multiple, alignment, trimming, large, scale, phylogenetic, analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
FIS ;
MEC
PMID:19505945 Free, Available for download, Freely available biotools:trimal https://vicfero.github.io/trimal/, https://bio.tools/trimal SCR_017334 2026-09-05 06:28:22 673
HomoplasyFinder
 
Resource Report
Resource Website
1+ mentions
HomoplasyFinder (RRID:SCR_017300) data analysis software, data processing software, software application, software resource, software toolkit, standalone software Software tool to identify and annotate homoplasies on phylogeny and sequence alignment. Used to automatically identify any homoplasies present in simulated and real phylogenetic data. Java application that can be used as standalone tool or within statistical programming environment R. homoplasy, phylogeny, sequence, alignment, identify, data, annotate Science Foundation Ireland PMID:30663960 Free, Available for download, Freely available https://github.com/JosephCrispell/homoplasyFinder SCR_017300 2026-09-05 06:28:22 6
BEAST2
 
Resource Report
Resource Website
100+ mentions
BEAST2 (RRID:SCR_017307) data analysis software, data processing software, sequence analysis software, software application, software resource, software toolkit Software package for advanced Bayesian evolutionary analysis by sampling trees. Used for phylogenetics, population genetics and phylodynamics. Program for Bayesian phylogenetic analysis of molecular sequences. Estimates rooted, time measured phylogenies using strict or relaxed molecular clock models. Framework can be extended by third parties. Comprised of standalone programs including BEAUti, BEAST, MASTER, RBS, SNAPP, MultiTypeTree, BDSKY, LogAnalyser, LogCombiner, TreeAnnotator, DensiTree and package manager. Bayesian, evolutionary, sampling, tree, phylogenic, analysis, Markov, chain, monte carlo, phylogenetic, population, genetic, phylodynamic, sequence is related to: BASTA
is related to: BEAST
is related to: PhyDyn
has parent organization: University of Auckland; Auckland; New Zealand
EMBL ;
European Research Council ;
Max Planck Society ;
NIGMS U01 GM110749;
Royal Society of New Zealand Marsden award ;
Swiss National Science foundation
PMID:30958812 Free, Available for download, Freely available SCR_017307 , Beast 2.5 2026-09-05 06:28:22 211

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