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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ProbeMatchDB 2.0
 
Resource Report
Resource Website
ProbeMatchDB 2.0 (RRID:SCR_003433) ProbeMatchDB analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Matches a list of microarray probes across different microrarray platforms (GeneChip, EST from different vendors, Operon Oligos) and species (human, mouse and rat), based on NCBI UniGene and HomoloGene. The capability to match protein sequence IDs has just been added to facilitate proteomic studies. The ProbeMatchDB is mainly used for the design of verification experiments or comparing the microarray results from different platforms. It can be used for finding equivalent EST clones in the Research Genetics sequence verified clone set based on results from Affymetirx GeneChips. It will also help to identify probes representing orthologous genes across human, mouse and rat on different microarray platforms. experiment, human, microarray, mouse, oligo, operon, platform, probe, protein, proteomic, rate, sequence, study, gene, est, cdna, sts marker, orthologous gene, ortholog, microarray probe, nucleotide sequence is related to: UniGene
is related to: HomoloGene
has parent organization: University of Michigan; Ann Arbor; USA
University of Michigan Microarray Network ;
Nancy Pritzker Depression Research Network ;
Department of Psychiatry pilot study ;
NIMH L99 MH60398;
NIDA R21 DA13754-01
PMID:11934751 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-33156 SCR_003433 2026-09-05 06:25:03 0
GMAP
 
Resource Report
Resource Website
500+ mentions
GMAP (RRID:SCR_008992) GMAP alignment software, data processing software, image analysis software, software application, software resource, source code THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. A software program for mapping and aligning cDNA sequences to a genome. The program maps and aligns a single sequence with minimal startup time and memory requirements, and provides fast batch processing of large sequence sets. The program generates accurate gene structures, even in the presence of substantial polymorphisms and sequence errors, without using probabilistic splice site models. Methodology underlying the program includes a minimal sampling strategy for genomic mapping, oligomer chaining for approximate alignment, sandwich DP for splice site detection, and microexon identification with statistical significance testing. mrna, est sequence, expressed sequence tag, sequence, cdna sequence, genome, cdna, bio.tools is used by: deFuse
is listed by: Debian
is listed by: bio.tools
has parent organization: Genentech
PMID:15728110 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_15072, biotools:gmap, nlx_152505 https://bio.tools/gmap, https://sources.debian.org/src/gmap/ SCR_008992 2026-09-05 06:26:31 599
CMAP
 
Resource Report
Resource Website
100+ mentions
CMAP (RRID:SCR_009034) CMap data analysis software, data processing software, software application, software resource Web-based tool that allows users to view comparisons of genetic and physical maps. The package also includes tools for curating map data. (entry from Genetic Analysis Software) gene, genetic, genomic, perl, unix, solaris, freebsd, linux, sequence, FASEB list is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: SoftCite
has parent organization: Generic Model Organism Database Project
works with: Drug Gene Budger
PMID:19648141 GNU General Public License nlx_153998, OMICS_00933 https://sourceforge.net/projects/gmod/files/cmap/ http://www.gmod.org/cmap/, http://gmod.org/wiki/Cmap SCR_009034 , GMOD Comparative Mapping (CMap) tool, Comparative Mapping tool, genetic and comparative maps 2026-09-05 06:26:32 417
eVOC
 
Resource Report
Resource Website
1+ mentions
eVOC (RRID:SCR_010704) eVOC controlled vocabulary, data or information resource, ontology THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented September 6, 2016. Set of orthogonal controlled vocabularies that unifies gene expression data by facilitating a link between the genome sequence and expression phenotype information. The system associates labelled target cDNAs for microarray experiments, or cDNA libraries and their associated transcripts with controlled terms in a set of hierarchical vocabularies. eVOC consists of four orthogonal controlled vocabularies suitable for describing the domains of human gene expression data including Anatomical System, Cell Type, Pathology and Developmental Stage. The four core eVOC ontologies provide an appropriate set of detailed human terms that describe the sample source of human experimental material such as cDNA and SAGE libraries. These expression terms are linked to libraries and transcripts allowing the assessment of tissue expression profiles, differential gene expression levels and the physical distribution of expression across the genome. Analysis is currently possible using EST and SAGE data, with microarray data being incorporated. The eVOC data is increasingly being accepted as a standard for describing gene expression and eVOC ontologies are integrated with the Ensembl EnsMart database, the Alternate Transcript Diversity Project and the UniProt Knowledgebase. Several groups are currently working to provide shared development of this resource such that it is of maximum use in unifying transcript expression information. mouse, mapping, cdna, development, microarray, expression, expressed sequence, anatomical system, cell type, developmental stage, experimental technique, microarray platform, pathology, pooling, tissue preparation, treatment, gene expression, genome sequence, expression phenotype, genome, sequence, phenotype, anatomical system, cell type, pathology, anatomy is related to: OBO
is related to: Bgee: dataBase for Gene Expression Evolution
has parent organization: University of the Western Cape; Bellville; South Africa
South African National Research Foundation ;
European Union ;
Wellcome Trust ;
South African Department of Arts Culture Science and Technology 32146
PMID:12799354 THIS RESOURCE IS NO LONGER IN SERVICE nlx_84448 SCR_010704 Expressed Sequence Annotation for Humans, eVOC (Expressed Sequence Annotation for Humans), eVOC Ontologies, eVOContology.org 2026-09-05 06:26:45 4
BioEdit
 
Resource Report
Resource Website
10000+ mentions
BioEdit (RRID:SCR_007361) alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource Software tool as biological sequence alignment editor written for Windows 95/98/NT/2000/XP/7 and sequence analysis program. Provides sequence manipulation and analysis options and links to external analysis programs to view and manipulate sequences with simple point and click operations., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence, alignment, editor, analysis, program is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE nlx_156845 SCR_007361 2026-09-05 06:26:10 13403
Olfactory Receptor DataBase
 
Resource Report
Resource Website
1+ mentions
Olfactory Receptor DataBase (RRID:SCR_007830) ORDB analysis service resource, data analysis service, data or information resource, data repository, database, production service resource, service resource, storage service resource Database of vertebrate olfactory receptors genes and proteins. It supports sequencing and analysis of these receptors by providing a comprehensive archive with search tools for this expanding family. The database also incorporates a broad range of chemosensory genes and proteins, including the taste papilla receptors (TPRs), vomeronasal organ receptors (VNRs), insect olfaction receptors (IORs), Caenorhabditis elegans chemosensory receptors (CeCRs), and fungal pheromone receptors (FPRs). ORDB currently houses chemosensory receptors for more than 50 organisms. ORDB contains public and private sections which provide tools for investigators to analyze the functions of these very large gene families of G protein-coupled receptors. It also provides links to a local cluster of databases of related information in SenseLab, and to other relevant databases worldwide. The database aims to house all of the known olfactory receptor and chemoreceptor sequences in both nucleotide and amino acid form and serves four main purposes: * It is a repository of olfactory receptor sequences. * It provides tools for sequence analysis. * It supports similarity searches (screens) which reduces duplicate work. * It provides links to other types of receptor information, e.g. 3D models. The database is accessible to two classes of users: * General public www users have full access to all the public sequences, models and resources in the database. * Source laboratories are the laboratories that clone olfactory receptors and submit sequences in the private or public database. They can search any sequence they deposited to the database against any private or public sequence in the database. This user level is suited for laboratories that are actively cloning olfactory receptors. fungal, pheromone receptor, gene, chemosensory, chemosensory receptor, g protein-coupled receptor, olfaction receptor, protein, receptor, taste papilla receptor, vomeronasal organ receptor, olfactory receptor, nucleotide, amino acid, chemoreceptor sequence, olfactory receptor sequence, chemoreceptor, sequence is used by: NIF Data Federation
is listed by: 3DVC
is related to: Odor Molecules DataBase
is related to: Integrated Manually Extracted Annotation
has parent organization: Yale School of Medicine; Connecticut; USA
Aging Human Brain Project ;
NIMH ;
NIA ;
NICD ;
NINDS ;
Multidisciplinary University Research Initiative ;
National Aeronautics and Space Administration ;
NIDCD RO1 DC 009977;
NIDCD P01 DC 04732;
NLM G08 LM05583
PMID:11752336
PMID:9847223
PMID:9218144
Public, Private, Acknowledgement requested, The community can contribute to this resource nif-0000-03213 SCR_007830 Olfactory Receptors Database 2026-09-05 06:26:15 4
Gene3D
 
Resource Report
Resource Website
100+ mentions
Gene3D (RRID:SCR_007672) Gene3D data access protocol, data or information resource, data repository, database, service resource, software resource, storage service resource, web service A large database of CATH protein domain assignments for ENSEMBL genomes and Uniprot sequences. Gene3D is a resource of form studying proteins and the component domains. Gene3D takes CATH domains from Protein Databank (PDB) structures and assigns them to the millions of protein sequences with no PDB structures using Hidden Markov models. Assigning a CATH superfamily to a region of a protein sequence gives information on the gross 3D structure of that region of the protein. CATH superfamilies have a limited set of functions and so the domain assignment provides some functional insights. Furthermore most proteins have several different domains in a specific order, so looking for proteins with a similar domain organization provides further functional insights. Strict confidence cut-offs are used to ensure the reliability of the domain assignments. Gene3D imports functional information from sources such as UNIPROT, and KEGG. They also import experimental datasets on request to help researchers integrate there data with the corpus of the literature. The website allows users to view descriptions for both single proteins and genes and large protein sets, such as superfamilies or genomes. Subsets can then be selected for detailed investigation or associated functions and interactions can be used to expand explorations to new proteins. The Gene3D web services provide programmatic access to the CATH-Gene3D annotation resources and in-house software tools. These services include Gene3DScan for identifying structural domains within protein sequences, access to pre-calculated annotations for the major sequence databases, and linked functional annotation from UniProt, GO and KEGG., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. protein domain, protein, protein superfamily, hidden markov model, structural domain, genome, sequence, domain assignments, protein structure, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: University College London; London; United Kingdom
NIH ;
Wellcome Trust ;
European Union FP6 ENFIN LSHG-CT-2003-503265;
European Union FP6 ENFIN LSHG-CT-2004-512092;
European Union FP6 ENFIN LSHG-CT-2005-518254;
DOE DE-AC02-065CH11357
PMID:19906693
PMID:18032434
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02877, biotools:gene3d https://bio.tools/gene3d SCR_007672 Gene3D - Structures assigned to Genomes 2026-09-05 06:26:14 272
Organelle DB
 
Resource Report
Resource Website
1+ mentions
Organelle DB (RRID:SCR_007837) Organelle DB d spatial image, data or information resource, data repository, database, image collection, service resource, storage service resource Database of organelle proteins, and subcellular structures / complexes from compiled protein localization data from organisms spanning the eukaryotic kingdom. All data may be downloaded as a tab-delimited text file and new localization data (and localization images, etc) for any organism relevant to the data sets currently contained in Organelle DB is welcomed. The data sets in Organelle DB encompass 138 organisms with emphasis on the major model systems: S. cerevisiae, A. thaliana, D. melanogaster, C. elegans, M. musculus, and human proteins as well. In particular, Organelle DB is a central repository of yeast protein localization data, incorporating results from both previous and current (ongoing) large-scale studies of protein localization in Saccharomyces cerevisiae. In addition, we have manually curated several recent subcellular proteomic studies for incorporation in Organelle DB. In total, Organelle DB is a singular resource consolidating our knowledge of the protein composition of eukaryotic organelles and subcellular structures. When available, we have included terms from the Gene Ontologies: the cellular component, molecular function, and biological process fields are discussed more fully in GO. Additionally, when available, we have included fluorescent micrographs (principally of yeast cells) visualizing the described protein localization. Organelle View is a visualization tool for yeast protein localization. It is a visually engaging way for high school and undergraduate students to learn about genetics or for visually-inclined researchers to explore Organelle DB. By revealing the data through a colorful, dimensional model, we believe that different kinds of information will come to light. gene, fly, vertebrate, human, mouse, plant, worm, yeast, protein, k-12, organelle, protein localization, function, subcellular structure, protein complex, sequence, annotation, micrograph, visualization, data analysis service is related to: Gene Ontology
has parent organization: University of Michigan; Ann Arbor; USA
American Cancer Society Research Scholar Grant RSG-06-179-01-MBC;
March of Dimes Basil O'Connor Starter Scholar Research award 5-FY05-1224;
NSF DBI-0543017
PMID:17130152
PMID:15608270
Free, Acknowledgement requested nif-0000-03226 SCR_007837 Organelle DB: A Database of Organelles and Protein Complexes 2026-09-05 06:26:15 7
Protein Mutant Database
 
Resource Report
Resource Website
1+ mentions
Protein Mutant Database (RRID:SCR_007878) PMD data or information resource, data repository, database, service resource, storage service resource It provides information on natural and artificial mutants, including random and site-directed ones, for all proteins except members of the globin and immunoglobulin families. The PMD is based on literature, and each entry in the database corresponds to one article which may describe one, several or a number of protein mutants. Each database entry is identified by a serial number and is defined as either natural or artificial, depending on the type of the mutation. For each entry the following are recorded : JOURNAL, TITLE, CROSS-REFERENCE, PROTEIN, N-TERMINAL, CHANGE, FUNCTION, STRUCTURE, STABILITY, etc. CROSS-REFERENCE indicates the code names of the protein given in other databases such as Protein Identification Resources (2). N-TERMINAL shows the N-terminal sequence of five amino acids which may help to show the unambiguous numbering of th e sequence. CHANGE indicates the position and kind of mutations, such as amino acid substitution, insertion and deletion, denoted with a specific notation. Any functional or structural features (FUNCTION, STRUCTURE, STABILITY,etc) observed in the mutant are described immediately after ''CHANGE''. Relative differences in activity and/or stability, in comparison with the wild-type protein, are indicated with symbols (- -),(-),(=),(+) or (+ +). Complete loss of activity is denoted as (0). Data Submission A data submission system was newly prepared in the PMD. We welcome the authors of articles published in academic journals to submit their own mutant data to the PMD. After checking the contents, we will register the data with a unique accession number. amino acid, artificial, deletion, insertion, mutant, natural, protein, sequence, substitution is related to: PredictSNP
has parent organization: National Institute of Genetics; Shizuoka; Japan
SCR_007878 Protein Mutant Database 2026-09-05 06:26:15 4
REBASE
 
Resource Report
Resource Website
100+ mentions
REBASE (RRID:SCR_007886) REBASE data or information resource, database Database of information about restriction enzymes and related proteins containing published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, methylation sensitivity, crystal, genome, and sequence data. DNA methyltransferases, homing endonucleases, nicking enzymes, specificity subunits and control proteins are also included. Several tools are available including REBsites, BLAST against REBASE, NEBcutter and REBpredictor. Putative DNA methyltransferases and restriction enzymes, as predicted from analysis of genomic sequences, are also listed. REBASE is updated daily and is constantly expanding. Users may submit new enzyme and/or sequence information, recommend references, or send them corrections to existing data. The contents of REBASE may be browsed from the web and selected compilations can be downloaded by ftp (ftp.neb.com). Additionally, monthly updates can be requested via email., endonuclease, enzyme, genome, archaeal, bacterial, cleavage, crystal, dna, individual protein family databases, isochizomer, methylation, methyltransferase, modification, protein, recognition, restriction, restriction enzyme, sensitivity, sequence, site, methylase, cleavage site, restriction-modification, blast, FASEB list has parent organization: New England Biolabs
works with: Webcutter
New England Biolabs Inc ;
NLM LM04971
PMID:19846593
PMID:17202163
r3d100012171, nif-0000-03391 http://rebase.neb.com, https://doi.org/10.17616/R3J930 http://www.neb.com/rebase SCR_007886 The Restriction Enzyme Database, Restriction Enzyme Database 2026-09-05 06:26:15 261
BovMap Database
 
Resource Report
Resource Website
1+ mentions
BovMap Database (RRID:SCR_008145) BovMap data or information resource, data repository, database, service resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. Database containing information on the cattle genome comprising loci list, phenes list, homology query, cattle maps, gene list, and chromosome homology. The objective of BovMap is to develop a set of anchored loci for the cattle genome map. In total, 58 clones were hybridized with chromosomes and identified loci on 22 of the 31 different bovine chromosomes. Three clones contained satellite DNA. Two or more markers were placed on 12 chromosomes. Sequencing of the microsatellites and flanking regions was performed directly from 43 cosmids, as previously reported. Primers were developed for 39 markers and used to describe the polymorphism associated with the corresponding loci. Users are also allowed to summit their own data for Bovmap. An integrated cytogenetic and meiotic map of the bovine genome has also been developed around the Bovmap database. One objective that Bovmap uses as the mapping strategy for the bovine genome uses large insert clones as a tool for physical mapping and as a source of highly polymorphic microsatellites for genetic typing. genetic, bovine, cattle, chromosome, clone, cosmid, cow, cytogenetic, dna, genome, homology, locus, meiotic, phene, polymorphism, sequence, map, gene has parent organization: INRA - French National Institute for Agricultural Research; Paris; France European Union THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-20968 SCR_008145 2026-09-05 06:26:18 2
E. coli Genome project
 
Resource Report
Resource Website
1+ mentions
E. coli Genome project (RRID:SCR_008139) data or information resource, database, portal, topical portal The E. coli Genome Project has the goal of completely sequencing the E. coli and human genomes. They began isolation of an overlapping lambda clonebank of E. coli K-12 strain MG1655. Those clones served as the starting material in our initial efforts to sequence the whole genome. Improvements in sequencing technology have since reached the point where whole-genome sequencing of microbial genomes is routine, and the human genome has in fact been completed. They initiated additional sequencing efforts, concentrating on pathogenic members of the family Enterobacteriaceae -- to which E. coli belongs. They also began a systematic functional characterization of E. coli K-12 genes and their regulation, using the whole genome sequence to address how the over 4000 genes of this organism act together to enable its survival in a wide range of environments. e. coli, enterobcteriaceae, gene, genome, human, journal aricle, knowledgebase, regulation, sequence, job has parent organization: University of Wisconsin-Madison; Wisconsin; USA NHGRI ;
NIAID
nif-0000-20961 SCR_008139 E.Coli genome project 2026-09-05 06:26:18 5
MitoRes
 
Resource Report
Resource Website
1+ mentions
MitoRes (RRID:SCR_008208) MitoRes data acquisition software, data analysis software, data processing software, software application, software resource MitoRes, is a comprehensive and reliable resource for massive extraction of sequences and sub-sequences of nuclear genes and encoded products targeting mitochondria in metazoa. It has been developed for supporting high-throughput in-silico analyses aimed to studies of functional genomics related to mitochondrial biogenesis, metabolism and to their pathological dysfunctions. It integrates information from the most accredited world-wide databases to bring together gene, transcript and encoded protein sequences associated to annotations on species name and taxonomic classification, gene name, functional product, organelle localization, protein tissue specificity, Enzyme Classification (EC), Gene Ontology (GO) classification and links to other related public databases. The section Cluster, has been dedicated to the collection of data on protein clustering of the entire catalogue of MitoRes protein sequences based on all versus all global pair-wise alignments for assessing putative intra- and inter-species functional relationships. The current version of MitoRes is based on the UniProt release 4 and contains 64 different metazoan species. The incredible explosion of knowledge production in Biology in the past two decades has created a critical need for bioinformatic instruments able to manage data and facilitate their retrieval and analysis. Hundreds of biological databases have been produced and the integration of biological data from these different resources is very important when we want to focus our efforts towards the study of a particular layer of biological knowledge. MitoRes is a completely rebuilt edition of MitoNuc database, which has been extensively modified to deal successfully with the challenges of the post genomic era. Its goal is to represent a comprehensive and reliable resource supporting high-quality in-silico analyses aimed to the functional characterization of gene, transcript and amino acid sequences, encoded by the nuclear genome and involved in mitochondrial biogenesis, metabolism and pathological dysfunctions in metazoa. The central features of MitoRes are: # an integrated catalogue of protein, transcript and gene sequences and sub-sequences # a Web-based application composed of a wide spectrum of search/retrieval facilities # a sequence export manager allowing massive extraction of bio-sequences (genes, introns, exons, gene flanking regions, transcripts, UTRs, CDS, proteins and signal peptides) in FASTA, EMBL and GenBank formats. It is an interconnected knowledge management system based on a MySQL relational database, which ensures data consistency and integrity, and on a Web Graphical User Interface (GUI), built in Seagull PHP Framework, offering a wide range of search and sequence extraction facilities. The database is compiled extracting and integrating information from public resources and data generated by the MitoRes team. The MitoRes database consists of comprehensive sequence entries whose core data are protein, transcript and gene sequences and taxonomic information describing the biological source of the protein. Additional information include: bio-sequences structure and location, biological function of protein product and dynamic links to both, external public databases used as data resources and public databases reporting complementary information. The core entity of the MitoRes database is represented by the protein so that each MitoRes entry is generated for each protein reported in the UniProt database as a nuclear encoded protein involved in mitochondrial biogenesis and function. Sponsors: MitoRes has been supported by Ministero Universit e Ricerca Scientifica, Italy (PRIN, Programma Biotecnologie legge 95/95-MURST 5, Proiect MURST Cluster C03/2000, CEGBA). Currently it is supported by operating grants from the Ministero dellIstruzione, dellUniversit e della Ricerca (MIUR), Italy (PNR 2001-2003 (FIRB art.8) D.M. 199, Strategic Program: Post-genome, grant 31-063933 and Project n.2, Cluster C03 L. 488/929). dysfunction, encode, enzyme, exon, extraction, function, functional, gene, alignment, amino acid, biogenesis, bioinformatic, biological, biology, cds, classification, disfunctional, genome, genomic, genomics, intron, localization, location, metabolic process, metabolism, metazoa, mitochondria, mitochondrial, mitochondrial genes and proteins databases, nuclear, nuclear_gene, nuclear_mitochondrial, nuclear_sequence, organelle, organelle localization, pathological, peptide, protein, protein_coding, protein structure classification, region, sequence, signal, signal_peptide, specie, specificity, structure, sub-sequence, taxonomic, tissue, transcript, utr nif-0000-21269 http://www2.ba.itb.cnr.it/MitoNuc/ SCR_008208 2026-09-05 06:26:19 1
MedBlast
 
Resource Report
Resource Website
1+ mentions
MedBlast (RRID:SCR_008202) software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. An algorithm that finds articles most relevant to a genetic sequence. In the genomic era, researchers often want to know more information about a biological sequence by retrieving its related articles. However, there is no available tool yet to achieve conveniently this goal. Here, a new literature-mining tool MedBlast is developed, which uses natural language processing techniques, to retrieve the related articles of a given sequence. An online server of this program is also provided. The genome sequencing projects generate such a large amount of data every day that many molecular biologists often encounter some sequences that they know nothing about. Literature is usually the principal resource of such information. It is relatively easy to mine the articles cited by the sequence annotation; however, it is a difficult task to retrieve those relevant articles without direct citation relationship. The related articles are those described in the given sequence (gene/protein), or its redundant sequences, or the close homologs in various species. They can be divided into two classes: direct references, which include those either cited by the sequence annotation or citing the sequence in its text; indirect references, those which contain gene symbols of the given sequence. A few additional issues make the task even more complicated: (1) symbols may have aliases; and (2) one sequence may have a couple of relatives that we want to take into account too, which include redundant (e.g. protein and gene sequences) and close homologs. Here the issues are addressed by the development of the software MedBlast, which can retrieve the related articles of the given sequence automatically. MedBlast uses BLAST to extend homology relationships, precompiled species-specific thesauruses, a useful semantics technique in natural language processing (NLP), to extend alias relationship, and EUtilities toolset to search and retrieve corresponding articles of each sequence from PubMed. MedBlast take a sequence in FASTA format as input. The program first uses BLAST to search the GenBank nucleic acid and protein non-redundant (nr) databases, to extend to those homologous and corresponding nucleic acid and protein sequences. Users can input the BLAST results directly, but it is recommended to input the result of both protein and nucleic acid nr databases. The hits with low e-values are chosen as the relatives because the low similarity hits often do not contain specific information. Very long sequences, e.g. 100k, which are usually genomic sequences, are discarded too, for they do not contain specific direct references. User can adjust these parameters to meet their own needs. gene, article, biological, data, genome, genomic, homolog, literature, medline interfaces, mining, molecular, protein, sequence, specie National Natural Science Foundation of China 39990600-03;
Knowledge Innovation Program of the Chinese Academy of Sciences KSCX2-2-07;
Knowledge Innovation Program of the Chinese Academy of Sciences KJCX1-08
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-21253 SCR_008202 MedBlast 2026-09-05 06:26:19 1
Parasite genome databases and genome research resources
 
Resource Report
Resource Website
1+ mentions
Parasite genome databases and genome research resources (RRID:SCR_008150) data or information resource, database, portal, topical portal This website contains information about the genomic sequence of parasites. It also contains multiple search engines to search six frame translations of parasite nucleotide databases for motifs, parasite protein databases for motifs, and parasite protein databases for keywords and text terms. * Guide to Internet Access to Parasite Genome Information * Guide to web-based analysis tools * Parasite Genome BLAST Server: Search a range of parasite specific nucleotide sequence databases with your own sequence. * Parasite Proteome Keyword Search Facility: Search parasite protein databases for keywords and text terms * Parasite Proteome Motif Search Facility: Search parasite protein databases for motifs * Parasite Six Frame Translation Motif Search Facility: Search six frame translations of parasite nucleotide databases for motifs * Genome computing resources: A list of ftp and gopher sites where genome computing applications and other resources can be found. genome, genomic, nucleotide, parasite, protein, proteome, sequence, gold standard has parent organization: European Bioinformatics Institute nif-0000-20981 SCR_008150 Parasite Genome Database 2026-09-05 06:26:18 2
Protein Databank Fun
 
Resource Report
Resource Website
1+ mentions
Protein Databank Fun (RRID:SCR_008226) data analysis software, data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. PDBfun is a web server for structural and functional analysis of proteins at the residue level. pdbFun gives fast access to the whole Protein Data Bank (PDB) organized as a database of annotated residues. The available data (features) range from solvent exposure to ligand binding ability, location in a protein cavity, secondary structure, residue type, sequence functional pattern, protein domain and catalytic activity. PDBfun is an integrated web tool for querying the PDB at the residue level and for local structural comparison. It integrates knowledge on single residues in protein structures coming from other databases or calculated with available or in-house developed instruments for structural analysis. Each set of different annotations represents a feature. Features are listed in PDBfun main page in orange. Features can be used for building residues selections. functional, 2d, ability, activity, analysis, binding, catalytic, cavity, chain, cleft, domain, ligand, location, motif, protein, protein structure databases, residue, secondary, sequence, size, solvent, structural, structure, surface THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-21315 SCR_008226 PDBfun 2026-09-05 06:26:19 2
Affymetrix Power Tools
 
Resource Report
Resource Website
10+ mentions
Affymetrix Power Tools (RRID:SCR_008401) software resource Affymetrix Power Tools (APT) are a set of cross-platform command line programs that implement algorithms for analyzing and working with Affymetrix GeneChip arrays. APT programs are intended for power users who prefer programs that can be utilized in scripting environments and are sophisticated enough to handle the complexity of extra features and functionality. APT provides platform for developing and deploying new algorithms without waiting for the GUI implementations. This resource is supported by Affymetrix, Inc. Affymetrix, Inc., Genomics, Clinical, Study, Bioinformatic, Windows, MacOS, Linux, resource, Data, Normalization, Sequence, Annotation, Gene, Expression, Pattern, Motif, Inference, Toolkit, Model, Fitting, Algorithm has parent organization: Affymetrix
has parent organization: Affymetrix
nif-0000-30070 https://www.affymetrix.com/support/developer/powertools/changelog/install.html, https://media.affymetrix.com/support/developer/powertools/changelog/index.html http://www.affymetrix.com/partners_programs/programs/developer/tools/powertools.affx SCR_008401 APT 2026-09-05 06:26:22 32
Joint Center for Structural Genomics
 
Resource Report
Resource Website
50+ mentions
Joint Center for Structural Genomics (RRID:SCR_008251) JCSG institution The JCSG is a multi-institutional consortium that aims to explore the expanding protein universe to find new challenges and opportunities to significantly contribute to new biology, chemistry and medicine through development of HT approaches to structural genomics. The mission of JCSG is to to operate a robust HT protein structure determination pipeline as a large-scale production center for PSI-2. A major goal is to ensure that innovative high-throughput approaches are developed that advance not only structural genomics, but also structural biology in general, via investigation of large numbers of high-value structures that populate protein fold and family space and by increasing the efficiency of structure determination at substantially reduced cost. The JCSG centralizes each core activity into single dedicated sites, each handling distinct, but interconnected objectives. This unique approach allows each specialized group to focus on its own area of expertise and provides well-defined interfaces among the groups. In addition, this approach addresses the requirements for the scalability needed to process large numbers of targets at a greatly reduced cost per target. JCSG production groups are: - Administrative Core - Bioinformatics Core - Crystallomics Core - Structure Determination Core - NMR Core JCSG is deeply committed to the development of new technologies that facilitate high throughput structural genomics. The areas of development include hardware, software, new experimental methods, and adaptation of existing technologies to advance genome research. In the hardware arena, their commitment is to the development of technologies that accelerate structure solution by increasing throughput rates at every stage of the production pipeline. Therefore, one major area of hardware development has been the implementation of robotics. In the software arena, they have developed enterprise resource software that track success, failures, and sample histories from target selection to PDB deposition, annotation and target management tools, and helper applications aimed at facilitating and automating multiple steps in the pipeline. Sponsors: The Joint Center for Structural Genomics is funded by the National Institute of General Medical Sciences (NIGMS), as part of the second phase of the Protein Structure Initiative (PSI) of the National Institutes of Health (U54 GM074898). exclusion chromatography, expression, fine-structure spectroscopy, fold, absorption, affinity, bacterial, baculovirus, bioinformatics, biology, biophysical, cell, chemistry, cloning, crystallization, crystallomics, differential scanning calorimetry, diffraction, domain, genomic, gnfuge, growth, hardware, ief gel electrophoresis, macromoleuclar, medicine, microexpression, mouse, nmr, optical density, physicochemical, protein, purification, recombinatorial, robotics, sds-page, sequence, software, structural, structural biology, structure, technology, thermocycler, topoisomerase, tryptic mass spectrometry, uv/vis absorbance scan, x-ray has parent organization: University of California at San Diego; California; USA
has parent organization: Scripps Research Institute
has parent organization: Sanford Burnham Prebys Medical Discovery Institute
has parent organization: Stanford University; Stanford; California
nif-0000-22295, grid.419677.a https://ror.org/00exr1241 SCR_008251 JCSG 2026-09-05 06:26:19 99
MAFFT
 
Resource Report
Resource Website
10000+ mentions
MAFFT (RRID:SCR_011811) MAFFT alignment software, data processing software, image analysis software, software application, software resource, software toolkit Software package as multiple alignment program for amino acid or nucleotide sequences. Can align up to 500 sequences or maximum file size of 1 MB. First version of MAFFT used algorithm based on progressive alignment, in which sequences were clustered with help of Fast Fourier Transform. Subsequent versions have added other algorithms and modes of operation, including options for faster alignment of large numbers of sequences, higher accuracy alignments, alignment of non-coding RNA sequences, and addition of new sequences to existing alignments. alignment, amino acid, nucleotide, sequence, DNA, sequence alignment, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
EMBL ;
Ministry of Education ;
Culture ;
Sports ;
Science and Technology of Japan
PMID:12136088
PMID:17118958
PMID:16362903
PMID:15661851
PMID:18439255
PMID:23023983
DOI:10.1093/bib/bbn013
biotools:MAFFT, OMICS_00979 https://www.ebi.ac.uk/Tools/msa/mafft/, https://www.genome.jp/tools-bin/mafft, https://myhits.isb-sib.ch/cgi-bin/mafft, https://bio.tools/MAFFT, https://sources.debian.org/src/mafft/ SCR_011811 Multiple Alignment using Fast Fourier Transform, MAFFT version 5, MAFFT version 7 2026-09-05 06:27:13 24687
Wellcome Trust Sanger Institute; Hinxton; United Kingdom
 
Resource Report
Resource Website
500+ mentions
Wellcome Trust Sanger Institute; Hinxton; United Kingdom (RRID:SCR_011784) WTSI, Sanger institution Non profit research organization for genome sequences to advance understanding of biology of humans and pathogens in order to improve human health globally. Provides data which can be translated for diagnostics, treatments or therapies including over 100 finished genomes, which can be downloaded. Data are publicly available on limited basis, and provided more extensively upon request. research, genome, sequence, human, health, project, global, data, treatment, therapy is listed by: re3data.org
is affiliated with: Open Targets
is related to: Clonalframe
is related to: ClonalOrigin
is related to: TraCeR
is parent organization of: ILLUMINUS
is parent organization of: ARNIE
is parent organization of: Sequence Search and Alignment by Hashing Algorithm
is parent organization of: Sequencing of Idd regions in the NOD mouse genome
is parent organization of: CAROL
is parent organization of: DINDEL
is parent organization of: Wellcome Trust Case Control Consortium
is parent organization of: OLORIN
is parent organization of: Exomiser
is parent organization of: COSMIC - Catalogue Of Somatic Mutations In Cancer
is parent organization of: GeneDB
is parent organization of: Breast Cancer Somatic Genetics Study
is parent organization of: Artemis: Genome Browser and Annotation Tool
is parent organization of: ACT: Artemis Comparison Tool
is parent organization of: Alien hunter
is parent organization of: Pfam
is parent organization of: DNAPlotter
is parent organization of: VAGrENT
is parent organization of: SMALT
is parent organization of: LookSeq
is parent organization of: ZMP
is parent organization of: Deciphering Developmental Disorders
is parent organization of: Sanger Mouse Resources Portal
is parent organization of: SpliceDB
is parent organization of: DECIPHER
is parent organization of: 1000 Genomes: A Deep Catalog of Human Genetic Variation
is parent organization of: Genes to Cognition: Neuroscience Research Programme
is parent organization of: MEROPS
is parent organization of: Rfam
is parent organization of: VEGA
is parent organization of: Bacterial Genomes
is parent organization of: Caenorhabditis Genome Sequencing Projects
is parent organization of: D. rerio Blast Server
is parent organization of: Fungi Sequencing Projects
is parent organization of: PEER
is parent organization of: Alfresco - FRont-End for Sequence COmparison
is parent organization of: AutoCSA (Automatic Comparative Sequence Analysis)
is parent organization of: AceDB
is parent organization of: CnD
is parent organization of: Genomics of Drug Sensitivity in Cancer
is parent organization of: Zebrafish Genome Project
is parent organization of: Tree families database
is parent organization of: Ensembl
is parent organization of: BamView
is parent organization of: SVMerge
is parent organization of: RetroSeq
is parent organization of: Consensus CDS
is parent organization of: WormBase
is parent organization of: Belvu
is parent organization of: Bio-tradis
is parent organization of: Blixem
is parent organization of: Dotter
is parent organization of: Exonerate
is parent organization of: Fastaq
is parent organization of: Gubbins
is parent organization of: CellPhoneDB
is parent organization of: Ensembl Metazoa
is parent organization of: Scmap
is parent organization of: Scfind
is parent organization of: Recognition of Errors in Assemblies using Paired Reads
is parent organization of: SAMTOOLS
is parent organization of: Cell Model Passports
Wellcome Trust ISNI: 0000 0004 0606 5382, nlx_91258, grid.10306.34, Wikidata: Q1142544 https://ror.org/05cy4wa09 SCR_011784 Wellcome Trust Sanger Institute, Genome Research Limited, The Wellcome Sanger Institute, Sanger Institute, Wellcome Trust Sanger Institute Genome Research Limited 2026-09-05 06:27:12 543

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