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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Ruby NIfTI
 
Resource Report
Resource Website
Ruby NIfTI (RRID:SCR_014164) software library, software toolkit, software resource A library for handling NIfTI data in the Ruby programming language. Ruby NIfTI supports basic read and write access to NIfTI files, including basic and extended header information and image information. It doesn't attempt to touch the image data but it does provide access to qform and sform orientation matrices. It also provides a nice interface to get at NIfTI info from within Ruby. nifti library, ruby, nifti is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Harvard University; Cambridge; United States
https://github.com/brainmap/nifti SCR_014164 2026-07-28 09:43:22 0
SCORE
 
Resource Report
Resource Website
100+ mentions
SCORE (RRID:SCR_014165) data or information resource, narrative resource, experimental protocol A collection of methods for comparing the performance of different image algorithms. These methods generate quantitative scores that measure divergences to a standard. experiment protocol, method, different image algorithm, quantitative score is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Utah; Utah; USA
NLM HHSN276201000584P;
NIBIB 1R41 EB011796
SCR_014165 2026-07-28 09:43:25 458
Principal Components Analysis of Scalar, Vector, and Mesh Vertex Data
 
Resource Report
Resource Website
Principal Components Analysis of Scalar, Vector, and Mesh Vertex Data (RRID:SCR_014163) software application, data analysis software, software resource, data processing software, image analysis software An implementation of standard PCA algorithms for use on scalar or vector data sets. Kernel PCA is implemented in this class, where the data sets are scalar or vector valued functions assigned at each of the points in a PointSet. A Gaussian Distance Kernel class is provided with the PCA class. pca algorithm, shape analysis, data analysis software, scalar data set, vector data set is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Johns Hopkins University; Maryland; USA
Available to the research community SCR_014163 2026-07-28 09:43:44 0
Advanced Connectivity Analysis (ACA)
 
Resource Report
Resource Website
1+ mentions
Advanced Connectivity Analysis (ACA) (RRID:SCR_014195) ACA software application, software resource, data processing software, data acquisition software A large scale functional connectivity data mining software package which enables large-scale seed-based analysis and brain-behavior analysis. It can examine a large number of seed regions with minimal user input. ACA has a brain-behavior analysis component to delineate associations among imaging biomarkers and one or more behavioral variables. data mining, data acquisition software, seed based analysis, brain behavior analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Available to the research community SCR_014195 Advanced Connectivity Analysis (ACA): a large scale functional connectivity data mining environment, Advanced Connectivity Analysis 2026-07-28 09:43:45 1
Optseq
 
Resource Report
Resource Website
100+ mentions
Optseq (RRID:SCR_014363) software application, data processing software, software resource, standalone software, data acquisition software Software tool for automatically scheduling events for rapid-presentation event-related (RPER) fMRI experiments (the schedule is the order and timing of events). Events in RPER are presented closely enough in time that their hemodynamic responses will overlap. This requires that the onset times of the events be jittered in order to remove the overlap from the estimate of the hemodynamic response. RPER is highly resistant to habituation, expectation, and set because the subject does not know when the next stimulus will appear or which stimulus type it will be. fmri, scheduling event, event, rper, hemodynamic response, stimulus, stochastic design is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Available for download SCR_005976, nlx_151349 http://www.nitrc.org/projects/optseq SCR_014363 Optseq2, Optseq - fMRI Event Scheduler 2026-07-28 09:43:25 332
Wisconsin Cortical Thickness Analysis (CTA) Toolbox
 
Resource Report
Resource Website
Wisconsin Cortical Thickness Analysis (CTA) Toolbox (RRID:SCR_014180) software application, data analysis software, software resource, data processing software, software toolkit A Matlab tool to perform statistical analysis on cortical thickness signals on brain surfaces obtained from Freesurfer. It is used for multi-resolutional analysis of such cortical thickness signals and detecting group differences. It is based on the Spectral Graph Wavelet Transform (SGWT) toolbox and provides plug and play methods for deriving Wavelet Multiscale Descriptor (WMD), cortical thickness smoothing using SGWT, Multivariate General Linear Model (MGLM), and False Discovery Rate (FDR). matlab, software toolkit, cortical thickness signal, data analysis software uses: FreeSurfer
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
Wisconsin Partnership Program ;
NIA R01AG040396;
NIA R01AG021155;
NSF RI 1116584;
NSF CAREER 1252725;
UW ADRC NIA P50 AG033514;
UW ICTR NCRR 1UL1RR025011;
NIA P30 AG010129;
NIA K01 AG030514
http://pages.cs.wisc.edu/~wonhwa/code/CTA_toolbox.html, http://pages.cs.wisc.edu/~wonhwa/project/ctdiscrim.html SCR_014180 2026-07-28 09:43:25 0
BraTumIA (Brain Tumor Image Analysis)
 
Resource Report
Resource Website
10+ mentions
BraTumIA (Brain Tumor Image Analysis) (RRID:SCR_014184) software application, software resource, data processing software, segmentation software, image analysis software Segmentation software for multimodal image analysis of brain tumor studies. It performs volumetric segmentation of healthy and tumor tissues by employing multispectral MRI sequences. Segmented tissues include Gray Matter, White Matter, Cerebrospinal Fluid, necrotic core, edema, non-enhancing tumor and enhancing tumor. segmentation software, image analysis, brain tumor, volumetric segmentation, mri is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is affiliated with: Cancer Imaging Archive (TCIA)
Free for non-commercial use only SCR_014184 BraTumIA 2026-07-28 09:43:22 13
Group Sparse Canonical Correlation Analysis
 
Resource Report
Resource Website
Group Sparse Canonical Correlation Analysis (RRID:SCR_014977) GSCCA software application, software resource, data analysis software, data processing software Group Sparse Canonical Correlation Analysis is a method designed to study the mutual relationship between two different types of data. group analysis, correlation analysis has parent organization: NeuroImaging Tools and Resources Collaboratory (NITRC) NSF ;
NIH
Available for download SCR_014977 2026-07-28 09:43:36 0
vIST/e
 
Resource Report
Resource Website
1+ mentions
vIST/e (RRID:SCR_001627) vIST/e software application, software toolkit, software resource, data processing software, image processing software, image analysis software Open source, platform-independent application for the visualization and analysis of complex, high-dimensional imaging data such as Diffusion Tensor Imaging (DTI) and High Angular Resolution Diffusion Imaging (HARDI). It has a plugin-based architecture which allows third parties to develop new plugins to extend the tool. Overview of the many features: * vIST/e is programmed in C++. It uses the Visualization Toolkit for visualization and pipelined data processing, as well as the cross-platform toolkit Qt Framework for an easy-to-use Graphical User Interface. * vIST/e introduces a powerful new plugin system, which allows for modular development with increased extensibility and stability. * Powerful GPU-based visualization techniques allow for smooth, real-time visualization of large data sets. Using custom ray tracing algorithms created with OpenGL, vIST/e can render DTI ellipsoids and HARDI spherical harmonics glyphs up to 4th order. The high frame rates offered by modern GPU technology allows for interactive exploration of this complex data. * Diffusion Tensor Imaging data can be visualized and interactively explored in a number of ways, including multiple cross-sections, volume rendering, and tensor glyphs. Derived scalar volumes, including various different anisotropy measures, can be computed and visualized. Data from other modalities, such as structural MRI, can be shown alongside the DTI data. * Various fiber tracking methods allow for fast and accurate reconstruction of fiber pathways. Interactively defined Regions of Interest (ROIs) can be used for seeding and filtering of fibers. Fibers are visualized either as lines, optionally using a powerful, GPU-based lighting engine, or as 3D structures such as tubes. * Scalar volumes, glyphs, and fibers can be colored using a wide array of coloring option. Customizable color loop-up tables allow for highly flexible visualization of scalar data. * Visualization and processing of various different HARDI formats is supported. HARDI data is interactively visualized using highly detailed glyphs rendered on the GPU. HARDI glyphs can be visualized in combination with DTI glyphs, for a better overview of complex diffusion data. * vIST/e includes support for NVIDIA's Compute Unified Device Architecture (CUDA), which enables highly parallel, GPU-based data processing, allowing for significant speed-up of computationally expensive algorithms. diffusion tensor imaging, high angular resolution diffusion imaging, visualization, cross-section, volume rendering, tensor glyph, mri, fiber tracking is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Diffusion MRI of Traumatic Brain Injury
has parent organization: Eindhoven University of Technology; North Brabant; Netherlands
Free, Available for download, Freely available nlx_153923 http://www.nitrc.org/projects/viste SCR_001627 DTITool 2026-07-28 09:40:14 4
Mind Research Network - COINS
 
Resource Report
Resource Website
10+ mentions
Mind Research Network - COINS (RRID:SCR_000805) COINS service resource, data set, data or information resource, data repository, storage service resource A web-based neuroimaging and neuropsychology software suite that offers versatile, automatable data upload/import/entry options, rapid and secure sharing of data among PIs, querying and export all data, real-time reporting, and HIPAA and IRB compliant study-management tools suitable to large institutions as well as smaller scale neuroscience and neuropsychology researchers. COINS manages over over 400 studies, more than 265,000 clinical neuropsychological assessments, and 26,000 MRI, EEG, and MEG scan sessions collected from 18,000 participants at over ten institutions on topics related to the brain and behavior. As neuroimaging research continues to grow, dynamic neuroinformatics systems are necessary to store, retrieve, mine and share the massive amounts of data. The Collaborative Informatics and Neuroimaging Suite (COINS) has been created to facilitate communication and cultivate a data community. This tool suite offers versatile data upload/import/entry options, rapid and secure sharing of data among PIs, querying of data types and assessments, real-time reporting, and study-management tools suitable to large institutions as well as smaller scale researchers. It manages studies and their data at the Mind Research Network, the Nathan Kline Institute, University of Colorado Boulder, the Olin Neuropsychiatry Research Center (at) Hartford Hospital, and others. COINS is dynamic and evolves as the neuroimaging field grows. COINS consists of the following collaboration-centric tools: * Subject and Study Management: MICIS (Medical Imaging Computer Information System) is a centralized PostgreSQL-based web application that implements best practices for participant enrollment and management. Research site administrators can easily create and manage studies, as well as generate reports useful for reporting to funding agencies. * Scan Data Collection: An automated DICOM receiver collects, archives, and imports imaging data into the file system and COINS, requiring no user intervention. The database also offers scan annotation and behavioral data management, radiology review event reports, and scan time billing. * Assessment Data Collection: Clinical data gathered from interviews, questionnaires, and neuropsychological tests are entered into COINS through the web application called Assessment Manager (ASMT). ASMT's intuitive design allows users to start data collection with little or no training. ASMT offers several options for data collection/entry: dual data entry, for paper assessments, the Participant Portal, an online tool that allows subjects to fill out questionnaires, and Tablet entry, an offline data entry tool. * Data Sharing: De-identified neuroimaging datasets with associated clinical-data, cognitive-data, and associated meta-data are available through the COINS Data Exchange tool. The Data Exchange is an interface that allows investigators to request and share data. It also tracks data requests and keeps an inventory of data that has already been shared between users. Once requests for data have been approved, investigators can download the data directly from COINS. mri, fmri, neuropsychological assessment, neuroimaging, diffusion tensor imaging assay, magnetic resonance imaging assay, functional mri assay, diffusion magnetic resonance imaging, magnetoencephalography, electroencephalography, brain, behavior, data sharing, data management, clinical, computed tomography, magnetic resonance, single photon emission computed tomography, positron emission tomography, clinical assessment clinical neuroinformatics, image collection, mri 2d image, database application is used by: Consortium for Reliability and Reproducibility
is used by: DataLad
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: NKI-RS Enhanced Sample
has parent organization: Mind Research Network
is parent organization of: MCIC
Aging NIBIB 1 R01 EB 000840;
NIBIB 1 R01 EB 006841;
NIBIB 1 R01 EB 005846
PMID:22275896 THIS RESOURCE IS NO LONGER IN SERVICE nlx_144067 http://www.nitrc.org/projects/coins SCR_000805 Mind Research Network - Collaborative Informatics and Neuroimaging Suite, Collaborative Informatics Neuroimaging Suite, Collaborative Informatics and Neuroimaging Suite 2026-07-28 09:40:04 20
TORTOISE
 
Resource Report
Resource Website
100+ mentions
TORTOISE (RRID:SCR_001645) TORTOISE software application, software resource, data processing software, image processing software, image analysis software An integrated and flexible software package for processing of DTI data, and in general for the correction of diffusion weighted images to be used for DTI and potentially for high angular resolution diffusion imaging (HARDI) analysis. It can be run on both Linux and Mac platforms. It is composed of two modules named DIFF PREP and DIFF CALC. * DIFF_PREP - software for image resampling, motion, eddy current distortion and susceptibility induced EPI distortion corrections, and for re-orientation of data to a common space * DIFF_CALC - software for tensor fitting, error analysis, color map visualization and ROI analysis In addition, TORTOISE contains additional Utilities, such as a tool for the analysis of multi-center phantom data. diffusion mri, dti, image motion correction, distortion correction, tensor computation, visualization, analysis, tensor fitting, modeling, magnetic resonance, tensor metric is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Diffusion MRI of Traumatic Brain Injury
has parent organization: National Institute of Child Health and Human Development
NICHD Free, Available for download, Freely available nlx_153921 http://www.nitrc.org/projects/tortoise SCR_001645 Tolerably Obsessive Registration and Tensor Optimization Indolent Software Ensemble 2026-07-28 09:40:14 101
Neurolucida
 
Resource Report
Resource Website
1000+ mentions
Neurolucida (RRID:SCR_001775) software application, data analysis software, software resource, data processing software, data visualization software Neurolucida is advanced scientific software for brain mapping, neuron reconstruction, anatomical mapping, and morphometry. Since its debut more than 20 years ago, Neurolucida has continued to evolve and has become the worldwide gold-standard for neuron reconstruction and 3D mapping. Neurolucida has the flexibility to handle data in many formats: using live images from digital or video cameras; stored image sets from confocal microscopes, electron microscopes, and scanning tomographic sources, or through the microscope oculars using the patented LucividTM. Neurolucida controls a motorized XYZ stage for integrated navigation through tissue sections, allowing for sophisticated analysis from many fields-of-view. Neurolucidas Serial Section Manager integrates unlimited sections into a single data file, maintaining each section in aligned 3D space for full quantitative analysis. Neurolucidas neuron tracing capabilities include 3D measurement and reconstruction of branching processes. Neurolucida also features sophisticated tools for mapping delineate and map anatomical regions for detailed morphometric analyses. Neurolucida uses advanced computer-controlled microscopy techniques to obtain accurate results and speed your work. Plug-in modules are available for confocal and MRI analysis, 3D solid modeling, and virtual slide creation. The user-friendly interface gives you rapid results, allowing you to acquire data and capture the full 3D extent of neurons and brain regions. You can reconstruct neurons or create 3D serial reconstructions directly from slides or acquired images, and Neurolucida offers full microscope control for brightfield, fluorescent, and confocal microscopes. Its added compatibility with 64-bit Microsoft Vista enables reconstructions with even larger images, image stacks, and virtual slides. Adding the Solid Modeling Module allows you to rotate and view your reconstructions in real time. Neurolucida is available in two separate versions Standard and Workstation. The Standard version enables control of microscope hardware, whereas the Workstation version is used for offline analysis away from the microscope. Neurolucida provides quantitative analysis with results presented in graphical or spreadsheet format exportable to Microsoft Excel. Overall, features include: - Tracing Neurons - Anatomical Mapping - Image Processing and Analysis Features - Editing - Morphometric Analysis - Hardware Integration - Cell Analysis - Visualization Features Sponsors: Neurolucida is supported by MBF Bioscience. electron microscope, fluorescent, 3d mapping, anatomical, brian, brightfield, camera, confocal, digital, hardware, mapping, microscope, morphometry, neuron, reconstruction, scanning tomographic, software, tissue, virtual, video, image is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) PMID:2224829 Restricted nif-0000-10294 http://www.nitrc.org/projects/neurolucida http://www.mbfbioscience.com/neurolucida/neurolucida SCR_001775 MBF Neurolucida 2026-07-28 09:40:16 3319
MEGSIM
 
Resource Report
Resource Website
MEGSIM (RRID:SCR_002420) MEGSIM software application, data set, data or information resource, software resource, simulation software Realistic simulated MEG datasets ranging from basic sensory to oscillatory sets that mimic functional connectivity; as well as basic visual, auditory, and somatosensory empirical sets. The simulated sets were created for the purpose of testing analysis algorithms across the different MEG systems when the truth is known. MEG baseline recordings were obtained from 5 healthy participants, using three MEG systems: VSM/CTF Omega, Elekta Neuromag Vectorview, 4-D Magnes 3600. Simulated signals were embedded within the CTF and Neuromag 306 baseline recordings (4-D to be added). Participant MRIs are available. Averaged simulation files are available as netcdf files. Neuromag 306 averaged simulations are also available in fif format. Also available: single trials of data where the simulated signal is jittered about a mean value, continuous fif files where the simulated signal is marked by a trigger, and simulations with oscillations added to mimic functional connectivity. eeg, meg, electrocorticography, forward - inverse, mri, meg modeling, model, simulation, os independent, test data, image collection is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Mind Research Network
NIMH R21MH080141 PMID:22068921 Free, Freely available nlx_155793 http://www.nitrc.org/projects/megsim SCR_002420 2026-07-28 09:40:26 0
Inter-Group Registration Toolbox
 
Resource Report
Resource Website
Inter-Group Registration Toolbox (RRID:SCR_002404) InterGroupReg software application, software resource, data processing software, registration software, image analysis software Software package that provides solutions for registering two groups of images, which are the necessary steps for many brain-related applications. magnetic resonance is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of North Carolina at Chapel Hill School of Medicine; North Carolina; USA
Free, Available for download, Freely available nlx_155777 http://www.nitrc.org/projects/intergroupreg SCR_002404 2026-07-28 09:40:25 0
Seg3D
 
Resource Report
Resource Website
100+ mentions
Seg3D (RRID:SCR_002552) Seg3D software application, rendering software, software resource, data processing software, data visualization software, image processing software, segmentation software, image analysis software A free volume processing segmenting tool that combines a flexible manual interface with powerful image processing and segmentation algorithms. Users can explore and label image volumes using slice windows and 3D volume rendering. analyze, c++, dicom, image display, linux, macos, microsoft, magnetic resonance, nrrd, posix/unix-like, rendering, segmentation, three dimensional display, visualization, volume rendering, win32 (ms windows), windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Utah; Utah; USA
NIGMS 8 P41 GM103545-15 PMID:29083867 Free, Available for download, Freely available nlx_155959 http://www.nitrc.org/projects/seg3d SCR_002552 2026-07-28 09:40:38 101
MindSeer
 
Resource Report
Resource Website
MindSeer (RRID:SCR_003019) MindSeer data visualization software, software resource, software application, data processing software A cross-platform application for 3D brain visualization for multi-modality neuroimaging data written in Java/Java3D, that runs in both standalone and client-server mode. It supports basic data management capabilities, visualization of 3D surfaces (SPM's output or OFF files), volumes (Analyze, NIFTI or Minc) and label sets. MindSeer has 2 different modes: # Client/Server is designed to allow users to visualize data that is stored centrally and enhance collaboration. # Standalone mode is available to view local data and is built for more performance than Client/Server Both modes have the same interface and support the same features. It has a modular architecture and is designed to be extensible. Requirements: # Java 5.0 or above. # Java Web Start. # Java3D (installed automatically by Web Start). 3d surface, visualization, multimodal, volume, neuroimaging, 3-d volume, surface, java, java3d, brain, brain structure, magnetic resonance is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
has parent organization: University of Washington; Seattle; USA
Human Brain Project ;
NIDCD DC02310
PMID:17937818 GNU General Public License, With some, GNU Lesser General Public License, Components (MatFile and NIFTI jar files). nif-0000-00525 http://www.nitrc.org/projects/mindseer SCR_003019 2026-07-28 09:40:34 0
SpineSegmentation module for 3DSlicer
 
Resource Report
Resource Website
1+ mentions
SpineSegmentation module for 3DSlicer (RRID:SCR_002593) Spine Segmentation Module in Slicer3 software application, software resource, data processing software, segmentation software, image analysis software 3D Slicer module for automated segmentation of the spine. This is an implementation of a novel model-based segmentation algorithm. This work was presented at the NA-MIC Week in Salt Lake City, Jan 2010. magnetic resonance, spine is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: 3D Slicer
has parent organization: National Alliance for Medical Image Computing
Free, Freely available nlx_155997 http://www.nitrc.org/projects/sylvainproject SCR_002593 Spine Segmentation module for 3D Slicer 2026-07-28 09:40:27 3
Nitime
 
Resource Report
Resource Website
10+ mentions
Nitime (RRID:SCR_002504) NiTime software application, data analysis software, software resource, data processing software, software library, software toolkit Software library for time-series analysis of data from neuroscience experiments. It contains a core of numerical algorithms for time-series analysis both in the time and spectral domains, a set of container objects to represent time-series, and auxiliary objects that expose a high level interface to the numerical machinery and make common analysis tasks easy to express with compact and semantically clear code. eeg, meg, electrocorticography, magnetic resonance, time-series, analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Neuroimaging in Python
Free, Available for download, Freely available nlx_155903 http://www.nitrc.org/projects/nitime SCR_002504 Nitime: time-series analysis for neuroscience 2026-07-28 09:40:37 22
brainGraph
 
Resource Report
Resource Website
10+ mentions
brainGraph (RRID:SCR_017260) software application, software resource, data analysis software, data processing software Software R package for performing graph theory analyses of brain MRI data. graph, theory, analysis, brain, MRI, data is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: CRAN
Free, Available for download, Freely available https://www.nitrc.org/projects/braingraph/, https://rdrr.io/cran/brainGraph/, https://www.r-pkg.org/pkg/brainGraph SCR_017260 brainGraph - Graph Theory Analysis of Brain MRI Data in R, brainGraph 2026-07-28 09:44:32 11
ReproNim/containers
 
Resource Report
Resource Website
1+ mentions
ReproNim/containers (RRID:SCR_018467) narrative resource, knowledge environment resource, data or information resource, software resource, workflow, software toolkit, portal, training material Software containerized environments for reproducible neuroimaging. Part of ReproNim - Center for Reproducible Neuroimaging Computation. DataLad dataset with collection of popular computational tools provided within ready to use containerized environments. Containerized environment, reproducible neuroimaging, ReproNim, neuroimaging, dataset, DataLad, imaging, data is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) NIBIB P41 EB019936;
NSF 1429999;
German Federal Ministry of Education and Research
Free, Freely available https://github.com/ReproNim/containers SCR_018467 2026-07-28 09:44:57 1

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