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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
casper
 
Resource Report
Resource Website
100+ mentions
casper (RRID:SCR_006613) casper software resource Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or greater biotools:casper, OMICS_01270 https://bio.tools/casper SCR_006613 casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads 2026-08-01 12:03:13 149
NIMH Repository and Genomics Resources
 
Resource Report
Resource Website
50+ mentions
NIMH Repository and Genomics Resources (RRID:SCR_006698) NRGR, RGR institution Collaborative venture between the National Institute of Mental Health (NIMH) and several academic institutions. Repository facilitates psychiatric genetic research by providing patient and control samples and phenotypic data for wide-range of mental disorders and Stem Cells.Stores biosamples, genetic, pedigree and clinical data collected in designated NIMH-funded human subject studies. RGR database likewise links to other repositories holding data from same subjects, including dbGAP, GEO and NDAR. Allows to access these data and biospecimens (e.g., lymphoblastoid cell lines, induced pluripotent cell lines, fibroblasts) and further expand genetic and molecular characterization of patient populations with severe mental illness. biosamples, genetic, pedigree, clinical, data is listed by: One Mind Biospecimen Bank Listing
is related to: NIMH Stem Cell Center
is related to: Rutgers Cell and DNA Repository
is related to: Sequenced Treatment Alternatives to Relieve Depression Study
is related to: CATIE - Clinical Antipsychotic Trials in Intervention Effectiveness
is related to: Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
is related to: NKI-RS Enhanced Sample
has parent organization: Rutgers University; New Jersey; USA
has parent organization: Washington University in St. Louis; Missouri; USA
has parent organization: University of Southern California; Los Angeles; USA
Bipolar Disorder, Schizophrenia, Alzheimer's disease, Autism, Attention deficit-hyperactivity disorder, Depression, Control, Obsessive-Compulsive Disorder, Anorexia Nervosa, Relative, Mental disorder, Brain disorder, Relative NIH Blueprint for Neuroscience Research ;
National Institute for Mental Health
Restricted grid.482687.7, nif-0000-00186, SCR_016318 https://ror.org/026dax180 SCR_006698 NIMH: Center for Collaborative Genetic Studies, NIMH Human Genetics Initiative, NIMH Center for Genetic Studies, NIMH Genetics, Center for Collaborative Genomic Studies on Mental Disorders, NIMH Repository and Genomics Resources (NRGR) 2026-08-01 12:03:15 66
ProSci
 
Resource Report
Resource Website
500+ mentions
ProSci (RRID:SCR_006609) commercial organization An Antibody supplier nlx_152435 SCR_006609 ProSci Incorporated, ProSci Inc 2026-08-01 12:03:10 808
Progen
 
Resource Report
Resource Website
1000+ mentions
Progen (RRID:SCR_006726) commercial organization Antibody and density gradient media supplier. nlx_152433 https://www.progen.de/ SCR_006726 2026-08-01 12:03:12 2056
SpliceTrap
 
Resource Report
Resource Website
10+ mentions
SpliceTrap (RRID:SCR_006728) SpliceTrap software resource A statistic tool for quantifying exon inclusion ratios in paired-end RNA-seq data, with broad applications for the study of alternative splicing. SpliceTrap approaches to exon inclusion level estimation as a Bayesian inference problem. For every exon it quantifies the extent to which it is included, skipped or subjected to size variations due to alternative 3?/5? splice sites or Intron Retention. In addition, SpliceTrap can quantify alternative splicing within a single cellular condition, with no need of a background set of reads. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
has parent organization: Cold Spring Harbor Laboratory
PMID:21896509 biotools:splicetrap, OMICS_01292 https://bio.tools/splicetrap SCR_006728 2026-08-01 12:03:18 16
BEDTools
 
Resource Report
Resource Website
10000+ mentions
BEDTools (RRID:SCR_006646) BEDTools software resource A powerful toolset for genome arithmetic allowing one to address common genomics tasks such as finding feature overlaps and computing coverage. Bedtools allows one to intersect, merge, count, complement, and shuffle genomic intervals from multiple files in widely-used genomic file formats such as BAM, BED, GFF/GTF, VCF. While each individual tool is designed to do a relatively simple task (e.g., intersect two interval files), quite sophisticated analyses can be conducted by combining multiple bedtools operations on the UNIX command line. genomics, bed, sam, bam, overlap, sequencing, intersect, coverage, gff, vcf, bedgraph, interval, genome arithmetic, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Hydra
is related to: pybedtools
is required by: SL-quant
PMID:20110278
DOI:10.1093/bioinformatics/btq033
GNU General Public License, v2, Acknowledgement requested OMICS_01159, biotools:bedtools https://code.google.com/p/bedtools/, https://bio.tools/bedtools, https://sources.debian.org/src/bedtools/ SCR_006646 bedtools - a swiss army knife for genome arithmetic, bedtools: a flexible suite of utilities for comparing genomic features 2026-08-01 12:03:11 10394
Down Syndrome Research and Treatment Foundation
 
Resource Report
Resource Website
Down Syndrome Research and Treatment Foundation (RRID:SCR_006637) DSRTF institution The Down Syndrome Research and Treatment Foundation is dedicated to finding a treatment to improve cognition including learning, memory and speech for individuals with Down syndrome. Since our founding in 2004 we have become the leading private source of funding in the United States for Down syndrome cognition research. The mission of DSRTF is to stimulate biomedical research that will accelerate the development of treatments to significantly improve cognition, including memory, learning and speech, for individuals with Down syndrome in order that they: * participate more successfully in school; * lead more active and independent lives; * and avoid the early onset of Alzheimer''s Disease. DSRTF is funding research that applies the information, tools and techniques resulting from the genome project along with recent advances in brain research to the study of cognition in Down syndrome. Our goal is the development of treatments that will improve learning, memory, and speech, and therefore enhance the lives of those with Down syndrome and their families. The majority of individuals with Down syndrome fall into the mild to moderate range of cognitive impairment. For many of these individuals, a 10%-20% improvement in cognitive ability would provide them with the ability to live independently, hold a job and be fully integrated within their communities. grid.478821.0, ISNI: 0000 0004 5902 2167, nlx_143653, Crossref funder ID: 100006836 https://ror.org/02m0a5h24 SCR_006637 2026-08-01 12:03:16 0
NiftySim
 
Resource Report
Resource Website
1+ mentions
NiftySim (RRID:SCR_006591) NiftySim software resource A high-performance nonlinear finite element solver. A key feature is the option of GPU-based execution, which allows the solver to significantly out-perform equivalent commercial packages. pet, spect is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University College London; London; United Kingdom
BSD License nlx_155900 http://www.nitrc.org/projects/niftysim SCR_006591 Nifty Sim 2026-08-01 12:03:15 3
LexGrid
 
Resource Report
Resource Website
1+ mentions
LexGrid (RRID:SCR_006627) LexGrid software resource LexGrid (Lexical Grid) provides support for a distributed network of lexical resources such as terminologies and ontologies via standards-based tools, storage formats, and access/update mechanisms. The Lexical Grid Vision is for a distributed network of terminological resources. It is the foundation of the National Center for Biomedical Ontology BioPortal interface and web-services, and can parse OBO format, as well as other formats such as OWL. Currently, there are many terminologies and ontologies in existence. Just about every terminology has its own format, its own set of tools, and its own update mechanisms. The only thing that most of these pieces have in common with each other is their incompatibility. This makes it very hard to use these resources to their full potential. We have designed the Lexical Grid as a way to bridge terminologies and ontologies with a common set of tools, formats and update mechanisms. The Lexical Grid is: * accessible through a set of common APIs * joined through shared indices * online accessible * downloadable * loosely coupled * locally extendable * globally revised * available in web-space on web-time * cross-linked The realization of this vision requires three interlocking components, which are: * Standards - access methods and formats need to be published and openly available * Tools - standards based tools must be readily available * Content - commonly used terminologies have to be available for access and download Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible software library, parse, ontology is listed by: BioPortal
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: OBO
has parent organization: European Bioinformatics Institute
has parent organization: National Cancer Institute
NIH ;
Cancer Biomedical Informatics Grid ;
NLM LM07319
PMID:19261933 Free for academic use nlx_149194 http://www.lexgrid.org/ SCR_006627 Lexical Grid 2026-08-01 12:03:16 1
ALEXA-Seq
 
Resource Report
Resource Website
1+ mentions
ALEXA-Seq (RRID:SCR_006700) ALEXA-Seq software resource A method for using massively parallel paired-end transcriptome sequencing for ''alternative expression analysis''. is listed by: OMICtools OMICS_01328 SCR_006700 2026-08-01 12:03:18 6
SpliceGrapher
 
Resource Report
Resource Website
10+ mentions
SpliceGrapher (RRID:SCR_006657) SpliceGrapher software resource Software that predicts alternative splicing patterns and produces splice graphs that capture in a single structure the ways a gene''s exons may be assembled. It enhances gene models using evidence from next-generation sequencing and EST alignments. is listed by: OMICtools
has parent organization: SourceForge
PMID:22293517 OMICS_01266 SCR_006657 2026-08-01 12:03:14 22
ChIPXpress
 
Resource Report
Resource Website
1+ mentions
ChIPXpress (RRID:SCR_006653) ChIPXpress software resource A R package designed to improve ChIP-seq and ChIP-chip target gene ranking using publicly available gene expression data. It takes as input predicted transcription factor (TF) bound genes from ChIPx data and uses a corresponding database of gene expression profiles downloaded from NCBI GEO to rank the TF bound targets in order of which gene is most likely to be functional TF target. gene expression, chip-seq, chip-chip, transcription factor, target gene, gene, gene expression profile is listed by: OMICtools
is related to: Gene Expression Omnibus
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00516 SCR_006653 ChIPXpress: enhanced transcription factor target gene identification from ChIP-seq and ChIP-chip data using publicly available gene expression profiles 2026-08-01 12:03:17 2
Promega
 
Resource Report
Resource Website
10000+ mentions
Promega (RRID:SCR_006724) commercial organization An Antibody supplier nlx_152434 SCR_006724 2026-08-01 12:03:18 93334
Web Game for Collaborative Labeling
 
Resource Report
Resource Website
1+ mentions
Web Game for Collaborative Labeling (RRID:SCR_006685) Web Game for Collaborative Labeling software resource Web game that provides an innovative infrastructure for labeling to enable an alternative to expert raters for medical image labeling through statistical analysis of the collaborative efforts of many, minimally-trained raters. Statistical atlases of regional brain anatomy have proven to be extremely useful in characterizing the relationship between the structure and function of the human nervous system. Typically, an expert human rater manually examines each slice of a three-dimensional volume. This approach can be exceptionally time and resource intensive, so cost severely limits the clinical studies where subject-specific labeling is feasible. Methods for improved efficiency and reliability of manual labeling would be of immense benefit for clinical investigation into morphological correlates of brain function. magnetic resonance, labeling, crowdsourcing is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) GNU Lesser General Public License nlx_156019 http://www.nitrc.org/projects/webmill SCR_006685 2026-08-01 12:03:14 2
SoftSearch
 
Resource Report
Resource Website
1+ mentions
SoftSearch (RRID:SCR_006683) SoftSearch software resource A sensitive structural variant (SV) detection software tool for Illumina paired-end next-generation sequencing data. It simultaneously utilizes soft-clipping and read-pair strategies for detecting SVs to increase sensitivity. Soft clips are proxies for split-reads that indicate part of the read maps to the reference genome, but the other part is not localized at the same place (e.g. breakpoint spanning reads). Discordant read-pairs refer to a read and its mate, where the insert size is greater (or less than) the expected distribution of the dataset ? or ? where the mapping orientation of the reads is unexpected (e.g. both on the same strand). SoftSearch looks for areas with soft-clipping in the genome that have discordant read pairs supporting the anomaly. Once areas with both these conditions are identified, the read and mate information is extracted directly from the BAM file containing the discordant reads, obviating the need for time-consuming and error-prone complex alignment strategies. Only a small number of soft-masked bases discordant read-pairs are necessary to identify an SV, which on their own would not be sufficient to make an SV call, thus highlighting SoftSearch?s improved sensitivity. SoftSearch is well suited to be ?plugged in? to most sequence analysis workflows, since it requires standard file inputs, such as a BAM file using almost any aligner and a reference genome FASTA file. Because SoftSearch requires soft-masked bases, the only requirement is that the aligner must have this functionality, which is usually turned on by default by many standard aligners (e.g. BWA, Novoalign, etc). illumina, structural variant, next-generation sequencing, perl, academic is listed by: OMICtools
has parent organization: Google Code
GNU General Public License, v2 OMICS_00322 SCR_006683 SoftSearch - Detecting Structural Variations Using Split Reads and Discordant Read Pairs 2026-08-01 12:03:17 5
GREC Corpus
 
Resource Report
Resource Website
1+ mentions
GREC Corpus (RRID:SCR_006719) GREC training set A semantically annotated corpus of 240 MEDLINE abstracts (167 on the subject of E. coli species and 73 on the subject of the Human species) intended for training information extraction (IE) systems and/or resources which are used to extract events from biomedical literature. The corpus has been manually annotated with events relating to gene regulation by biologists. Each event is centered on either a verb (e.g. transcribe) or nominalized verb (e.g. transcription) and annotation consists of identifying, as exhaustively as possible, the structurally-related arguments of the verb or nominalized verb within the same sentence. Each event argument is then assigned the following information: * A semantic role from a fixed set of 13 roles which are tailored to the biomedical domain. * A biomedical concept type (where appropriate). The corpus in available for download in 2 formats: * A standoff format, based on the BioNLP'09 Shared Task format * An XML format, based on the GENIA event annotation format annotation, information extraction, text mining, semantic role, semantic search, gene, computational linguistics, gene regulation is listed by: FORCE11
is related to: MEDLINE
has parent organization: National Centre for Text Mining
JISC PMID:19852798 Creative Commons Attribution-NonCommercial-ShareAlike License, v3 Unported, For Copyright of abstracts refer to PubMed. nif-0000-06688 SCR_006719 Gene Event Regulation Corpus 2026-08-01 12:03:18 3
Med Associates: Deluxe Behavioral Test Package with Rat Modular Chamber
 
Resource Report
Resource Website
1+ mentions
Med Associates: Deluxe Behavioral Test Package with Rat Modular Chamber (RRID:SCR_021938) instrument resource Operant behavior test package for rat built to meet needs of research studies requiring additional reward and stimulus flexibility. One of Med Associates, Inc. operant conditioning and general behavior product. Med Associates, Inc., operant behavior test package, stimulus flexibility, additional reward Commercially available SCR_021938 Deluxe Behavioral Test Package w/Rat Modular Chamber 2026-08-01 12:07:19 3
University of Southern Denmark; Denmark
 
Resource Report
Resource Website
1+ mentions
University of Southern Denmark; Denmark (RRID:SCR_021943) SDU university University has campuses located in Southern Denmark and on Zealand with main campus in Odense and regional campuses in Slagelse, Kolding, Esbjerg and Sønderborg. University offers joint programes in co-operation with University of Flensburg and University of Kiel. is parent organization of: PolySTest SCR_021943 2026-08-01 12:07:20 1
Alveole Leonardo
 
Resource Report
Resource Website
1+ mentions
Alveole Leonardo (RRID:SCR_021940) software resource Photopatterning software to control PRIMO system including UV illumination module, microscope, camera and stage, and to precisely define experimental conditions.Used to design your own micropatterning manipulations. Alvéole, control PRIMO system, micropatterning manipulations design is related to: Alveole: PRIMO photopatterning module Restricted SCR_021940 Alvéole Leonardo software, Leonardo software 2026-08-01 12:07:20 1
Alveole: PRIMO photopatterning module
 
Resource Report
Resource Website
1+ mentions
Alveole: PRIMO photopatterning module (RRID:SCR_021941) PRIMO instrument resource Photopatterning device for performing micropatterning, microfabrication and hydrogel polymerization.Part of PRIMO system. Alvéole, photopatterning module, micropatterning, microfabrication, hydrogel polymerization, instrument, equipment is related to: Alveole Leonardo Restricted https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_021941.pdf SCR_021941 Alvéole PRIMO, Alveole PRIMO 2026-08-01 12:07:27 1

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