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http://www.med.upenn.edu/idom/drc/cores/transmouse.html

Mouse core which generates transgenic and gene-targeted mouse lines for diabetes research.

Proper citation: Penn Diabetes Research Center Transgenic and Chimeric Mouse Core Facility (RRID:SCR_010036) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/community/profile/id/1133

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides training and expertise in nutrition/diet methodology to obtain valid and reliable assessment and analyses of dietary intakes, nutritional status, body composition and metabolism.

Proper citation: Vanderbilt Diabetes Research and Training Center Vanderbilt Diet Body Composition and Metabolism Core Facility (RRID:SCR_010191) Copy   

•   Source: SciCrunch Registry

https://einsteinmed.edu/research/shared-facilities/barc/

Core provides information and tools for Einstein and Montefiore investigators from initial study planning stage through analysis and data output. Facility services include: mass spectrometry analysis, including stable isotopes, as well as research-grade determination of lipids, and metabolic markers for human subjects and animal model projects; High-throughput robotics for semi-automated high-quality sample preparation and analysis by immunoassay and liquid chromatography–mass spectrometry (LC/MS); Support for novel developmental projects featuring applications of LC/MS and two-site bead-based assays; Research quality analysis of metabolites for human and animal samples using Olympus AU400 autoanalyzer; Advanced training in analytical chemistry.

Proper citation: Einstein-Mount Sinai Diabetes Research Center Biomarker Analytic Research Core Facility (RRID:SCR_015067) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/diabetes-research/diabetes.aspx?id=1566&ekmensel=15074e5e_4046_4048_28715_1

Core which uses stable isotope flux and metabolite profiling to help formulate and test hypotheses about the metabolic consequences of various changes in gene expression and protein function, in order to guide further integrative systems biology analyses of the underlying mechanisms in diabetes, insulin resistance, obesity, and diabetic complications.

Proper citation: Einstein-Mount Sinai Diabetes Research Center Stable Isotope and Metabolomics Core Facility (RRID:SCR_015071) Copy   

•   Source: SciCrunch Registry

http://clinicaltrials.gov/show/NCT00143949

Randomized, multicenter, double-blind study to determine if renin angiotensin medications, either losartan (angiotensin II blocker) or enalapril (converting enzyme inhibitor), can prevent or delay the onset of diabetic kidney disease in patients with type 1 diabetic patients who do not have hypertension, diabetic nephropathy, or predictive levels of microalbuminuria. Two hundred eight five patients ages 16-61 with 2-20 yrs of Type 1 Diabetes Mellitus and no renal functional abnormalities were randomized into a parallel, double-blind, placebo-controlled study involving 3 groups (95 patients/group). Each group received an angiotensin-converting enzyme inhibitor (ACEI) (enalapril), or an angiotensin II receptor blocker (Losartan), or placebo. All patients had their usual Diabetes Mellitus (DM) management. Baseline studies included measures of glomerular filtration rate (GFR), urinary albumin excretion rate (UAE), blood pressure (BP), and a percutaneous renal biopsy. Patients were followed by quarterly measures of BP, HbA1C, UAE, and drug compliance. There were annual measures of GFR and a repeat renal biopsy after 5 yrs in the study. The main endpoint is kidney structural changes over time, especially mesangial fractional volume (v(Mes/glom)). Secondary endpoints will be other DN structural measures and measures of kidney function (UAE, GFR). These studies will determine whether rennin angiotensin system blockage in the early stages of DN can prevent the early kidney structural changes in this important disorder. Ancillary studies will evaluate the effects of treatment group on the development and progression of diabetic retinopathy and will develop predictors of study participants'''' compliance. Baseline, 2.5 and 5 year retinal fundus photographs in the RASS patients were obtained.

Proper citation: Renin Angiotensin System Study (RRID:SCR_013385) Copy   

•   Source: SciCrunch Registry

http://www.ukbiobank.ac.uk/

Biobank provides data collected at Assessment Center and via online questionnaires on participants aged 40-69 years recruited throughout United Kingdom and provides summary information to improve prevention, diagnosis and treatment of serious and life threatening illnesses.

Proper citation: UK Biobank (RRID:SCR_012815) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/diabetes-translational-research/latino-network/

Research network dedicated to supporting translation research in diabetes prevention and control. The core has a strong emphasis on sociocultural adaption for Latinos in the U.S and can provide expertise in Latino biopsychosocial research.

Proper citation: New York Regional Center for Diabetes Translation Research Latino Network for Diabetes Translational Research (RRID:SCR_015189) Copy   

•   Source: SciCrunch Registry

http://diabetesresearch.med.umich.edu/Core_MCDTR_Methods.php

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Research core that works to assist investigators in designing studies, collecting data, and analyzing data to examine questions related to the causes, prevention, and control of diabetes, its complications, and comorbidities.

Proper citation: Michigan Center for Diabetes Translational Research Methods and Measurements Core (RRID:SCR_015188) Copy   

•   Source: SciCrunch Registry

http://www.einstein.yu.edu/centers/diabetes-translational-research/timc/

Core facility that supports research that addresses the prevention and control of diabetes using a social-ecological approach to address the dynamic interrelations of biological, psychological and social factor at a personal and environmental level.

Proper citation: New York Regional Center for Diabetes Translation Research Translational Intervention Methodology Core (RRID:SCR_015180) Copy   

•   Source: SciCrunch Registry

http://drc.ucsf.edu/mouse-genetics-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 5,2024. Core that provides a shared resource for the establishment of mutant mouse models for DRC research. It coordinates DRC members with contacts to a number of UCSF-wide facilities for knock-out/knock-in and transgenic mouse generation.

Proper citation: University of California San Francisco Diabetes Research Center Mouse Genetics Core Facility (RRID:SCR_015109) Copy   

•   Source: SciCrunch Registry

http://www.uab.edu/shp/drc/administrative-core-links

Core responsible for the scientific, education/enrichment, and fiscal operations of the DRC. Their goal is to assure the growing vitality of an intellectual community and a highly productive research program in diabetes by effective deployment of DRC resources for the benefit of our investigators, patients, and trainees.

Proper citation: University of Alabama at Birmingham Diabetes Research Center Administrative Core Facility (RRID:SCR_015108) Copy   

•   Source: SciCrunch Registry

http://www.uab.edu/shp/drc/bioanalytical-redox-biology-core-barb-links

Core which promotes redox biology in diabetes-related research. It promotes research in areas common to the metabolic and vascular aspects of diabetes and cardiovascular disease. The core provides services in mitochondrial damage, function, proteomics, and oxidative stress assessment support for investigators carrying out diabetes mellitus (DM) and cardiometabolic disease (CMD) research at UAB.

Proper citation: University of Alabama at Birmingham Diabetes Research Center Bioanalytical REDOX Biology Core Facility (RRID:SCR_015113) Copy   

•   Source: SciCrunch Registry

https://www.derc.cuimc.columbia.edu/services/translational-biomarker-analytical-core

Core makes available to Diabetes Research Center investigators variety of high quality radio-immunoassay, ELISA, and other analytical methods, and facilitates access of DRC investigators to measurement of small molecules by targeted and untargeted metabolomics/lipidomics with the Irving Institute Biomarkers Core. TBAC also provides consultations and services for in vivo methods to measure insulin secretion and sensitivity.

Proper citation: Columbia Diabetes Research Center Translational Biomarker Analytical Core Facility (RRID:SCR_015077) Copy   

•   Source: SciCrunch Registry

https://cdtr.wustl.edu/our-cores/communication-and-literacy/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 15,2026. Core facility whose services include assisting with outreach and recruitment to various populations, developing strategic community partnerships, and developing materials and methods for effective health education within the community.

Proper citation: Washington University Center for Diabetes Translation Research Health Communication and Health Literacy Core Facility (RRID:SCR_015198) Copy   

•   Source: SciCrunch Registry

http://www.uab.edu/shp/drc/human-physiology-core-links

Core which incorporates and combines expertise and technology for assessment of hormones and other analytes in both humans and animal models; body composition and fat distribution; insulin sensitivity and substrate metabolism; energy expenditure; and cardiovascular function.

Proper citation: University of Alabama at Birmingham Diabetes Research Center Human Physiology Core Facility (RRID:SCR_015111) Copy   

•   Source: SciCrunch Registry

http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/genomics.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Core that provides services in genotyping, sequencing, biobanks, and genetic epidemiology. It also offers access to the Amish exome variant database, basic molecular services, and viral vector construction and development.

Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Molecular and Translational Genomics Core (RRID:SCR_015116) Copy   

•   Source: SciCrunch Registry

http://diabetesresearch.med.umich.edu/Core_MDRC_OMICS.php

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Core that supports the use of the OMICS technologies by MDRC members (specifically on projects relevant to diabetes and related endocrine and metabolic disorders, including their complications) by supporting pilot studies that utilize these technologies.

Proper citation: Michigan Diabetes Research Center OMICS Core (RRID:SCR_015117) Copy   

•   Source: SciCrunch Registry

https://einsteinmed.edu/centers/diabetes-research/biomedical-cores/animal-physiology/

Core which assists with the in vivo assessment of glucose and fatty acid metabolism, insulin sensitivity and energy homeostasis in mice and rats. It provides tools to understand the behavior and physiology mediating the relationships among diabetes, nutrient sensing, obesity and diabetic cardiovascular complications in rodents.

Proper citation: Einstein-Mount Sinai Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015076) Copy   

•   Source: SciCrunch Registry

https://diabetes.med.umich.edu/partners/michigan-center-diabetes-translational-research-mcdtr/cores-and-programs/administration

Administrative core for the Michigan Center for Diabetes Translational Research. It works to raise awareness of and interest in type 2 diabetes research, manage its grant program, and support investigators working on both clinical and implementationl diabetes research.

Proper citation: Michigan Center for Diabetes Translational Research Administrative Core Facility (RRID:SCR_015194) Copy   

•   Source: SciCrunch Registry

http://www.baderc.org/cores/transgenicCore.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 23,2024.Transgenic core which generates transgenic and gene knockout mouse models relevant to obesity, diabetes and nutrition research. It also provides consultation on all aspects of making transgenic and gene knockout mice.

Proper citation: Boston Area Diabetes Endocrinology Research Center Transgenic (RRID:SCR_015074) Copy   

•   Source: SciCrunch Registry