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URL: http://www.wormbase.org/db/get?name=WBStrain00034597
Proper Citation: RRID:WB-STRAIN:WBStrain00034597
Description: Caenorhabditis elegans with name lin-5(n3070)/mnC1 [dpy-10(e128) unc-52(e444)] II. from WB.
Species: Caenorhabditis elegans
Synonyms: lin-5(n3070)/mnC1 [dpy-10(e128) unc-52(e444)] II.
Notes: Heterozygotes are WT and segregate WT, Stu and DpyUncs. n3070 is a strong loss-of-function or null allele. Molecular lesion: P to S at position 24 as well as an amber mutation terminating translation after amino acid 52. DNA replication continues in the absence of mitosis. Mutants enter mitotis at the normal time and form bipolar spindles, but fail chromosome alignment at the metaphase plate, sister chromatid separation and cytokinesis.
Affected Gene: WBGene00001072(dpy-10)|WBGene00002994(lin-5)|WBGene00006787(unc-52)
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Source: Integrated Animals
Source Database: WormBase (WB)