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Proper Citation: RRID:MGI:3800941
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal long bone epiphyseal plate proliferative zone, decreased osteoclast cell number, increased width of hypertrophic chondrocyte zone, abnormal chondrocyte differentiation, abnormal pelvic girdle bone morphology, decreased length of long bones, increased long bone epiphyseal plate size, short tibia, abnormal chondrocyte morphology, increased diameter of tibia, failure of tooth eruption, decreased osteoclast cell number, abnormal long bone epiphyseal plate morphology, abnormal spleen marginal zone morphology, abnormal spleen morphology, short vertebral column, abnormal spleen B cell follicle morphology, decreased cranium height, absent cervical lymph nodes, abnormal cervical lymph node morphology, absent peripheral lymph nodes, absent mesenteric lymph nodes, decreased Peyer's patch number, optic canal stenosis, abnormal thymus cell ratio, abnormal splenic cell ratio, abnormal lung morphology, abnormal long bone internal diameter, abnormal bone marrow morphology, decreased bone marrow cell number, decreased bone mineral density, decreased bone trabecula number, decreased circulating calcium level, decreased spleen white pulp amount, extramedullary hematopoiesis, failure of tooth eruption, increased bone mineral density, increased bone mineralization, increased bone volume, increased spleen red pulp amount, increased trabecular bone thickness, osteopetrosis, small thymus medulla, small Peyer's patches, decreased body weight, decreased Langerhans cell number
Affected Gene: Tnfsf11
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI