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Proper Citation: RRID:MGI:3618247
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased interleukin-12 secretion, decreased circulating interleukin-6 level, increased susceptibility to bacterial infection, increased marginal zone B cell number, abnormal T cell subpopulation ratio, increased CD8-positive, alpha-beta T cell number, decreased interleukin-10 secretion, abnormal B cell number, decreased interleukin-6 secretion, decreased tumor necrosis factor secretion, decreased follicular B cell number, decreased circulating tumor necrosis factor level, impaired macrophage phagocytosis, decreased IgM level
Affected Gene: Siglec1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
