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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092603
Proper Citation: RRID:RGD_598092603
Description: Rattus norvegicus with name F344-Cybbem1ShmoNox1em1ShmoNox4em1Shmo from RGD.
Species: Rattus norvegicus
Notes: A 7-base deletion in the first exon of the NADPH oxidase 2 (Nox2) gene, a 29-base deletion in the first exon of the NADPH oxidase 1 (Nox1) gene, and a one-base insertion in the first exon of the NADPH oxidase 4 (Nox4) gene were introduced by CRISPR/Cas9 in the F344/DuCrj rats. They were then backcrossed to F344/N (Japan SLC, Inc.). This triple Nox knock rats were created by compound crossbreeding of single knockout rats (RGD:598092598, RGD:598092601, RGD:598092602). National BioResource Project for the Rat in Japan
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
