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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430169
Proper Citation: RRID:RGD_156430169
Description: Rattus norvegicus with name SD-Mecp2em1Sage/Hsd from RGD.
Species: Rattus norvegicus
Notes: The MeCP2 KO rat model was originally created at SAGE Labs, Inc. in St. Louis, MO and distributed out of the Boyertown, PA facility. The line continues to be maintained through the original SAGE Labs animal inventory acquired by Envigo. The ZFN mutant rat strain was produced by injecting zinc finger nuclease targeting rat Mecp2 into Sprague Dawley embryos. This mutant rat has a knockout of the methyl CpG binding protein 2 (Mecp2). ENVIGO
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No rating or validation information has been found for SD-Mecp2em1Sage/Hsd.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)