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Proper Citation: RRID:MGI:4354628
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased B cell number, abnormal lymphocyte morphology, increased double-positive T cell number, increased activated T cell number, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased CD8-positive, alpha-beta T cell number, decreased CD4-positive, alpha beta T cell number, increased T cell number, abnormal Peyer's patch morphology, abnormal choroid plexus morphology, abnormal CD4-positive, alpha-beta T cell physiology, abnormal CD4-positive, alpha beta T cell morphology, decreased IgG3 level, decreased interleukin-12 secretion, increased IgM level, abnormal gut-associated lymphoid tissue morphology, decreased tumor necrosis factor secretion, increased B-1 B cell number, increased susceptibility to viral infection, abnormal Peyer's patch germinal center morphology, abnormal intraepithelial T cell number, decreased IgA level, decreased macrophage cytokine production, abnormal macrophage physiology, abnormal myeloid dendritic cell morphology, decreased macrophage nitric oxide production, abnormal peritoneal macrophage morphology, decreased inflammatory response, decreased interleukin-10 secretion
Affected Gene: Ccr6
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No rating or validation information has been found for Ccr6tm1Lira/Ccr6tm1Lira.
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
