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Proper Citation: RRID:MGI:3717151
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased IgM level, abnormal marginal zone B cell physiology, abnormal CD4-positive T cell differentiation, abnormal CD8-positive, alpha-beta T cell differentiation, decreased tumor necrosis factor secretion, abnormal humoral immune response, abnormal immune system organ morphology, decreased interleukin-10 secretion, decreased interleukin-2 secretion, abnormal B cell morphology, decreased marginal zone B cell number, lymphoid hypoplasia, abnormal T cell morphology, decreased IgG2a level, decreased IgG1 level, decreased interleukin-4 secretion, decreased double-positive T cell number, decreased IgG level, decreased T cell proliferation, decreased interferon-gamma secretion, increased length of allograft survival, abnormal inflammatory response, abnormal B cell physiology, decreased Peyer's patch number
Affected Gene: Sash3
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No rating or validation information has been found for Sash3tm1Hlz/Sash3tm1Hlz.
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
