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Proper Citation: RRID:MGI:3714016
Description: Allele Detail: Transgenic, Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Transgenic, Targeted This is a legacy resource.
Phenotype: decreased hippocampus pyramidal cell number, increased brain size, megacephaly, abnormal spike wave discharge, abnormal Purkinje cell morphology, abnormal cerebellum morphology, abnormal cerebellar molecular layer, abnormal cerebellum external granule cell layer morphology, ataxia, hippocampal neuron degeneration, hydrocephaly, increased brain size, lethargy, abnormal dentate gyrus morphology, abnormal hippocampus morphology, abnormal cerebellar granule cell morphology, abnormal cerebellar foliation, decreased Purkinje cell number, increased hamartoma incidence, seizures, neuron hypertrophy, ataxia, premature death, gliosis, premature death, abnormal hippocampus pyramidal cell layer, tonic-clonic seizures, megacephaly
Affected Gene: Pten
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No rating or validation information has been found for Tg(Gfap-cre)1Sbk; Ptentm2Mak/Ptentm2Mak.
No alerts have been found for Tg(Gfap-cre)1Sbk; Ptentm2Mak/Ptentm2Mak.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI