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Proper Citation: RRID:MGI:3706343
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased B cell number, premature death, increased urinary system tumor incidence, increased skin tumor incidence, increased incidence of tumors by chemical induction, increased cellular sensitivity to gamma-irradiation, decreased incidence of tumors by ionizing radiation induction, decreased mortality induced by ionizing radiation, increased sebaceous gland adenoma incidence, glomerulonephritis, increased hemangiosarcoma incidence, increased B cell derived lymphoma incidence, abnormal self tolerance, enlarged spleen, glomerulonephritis, increased anti-double stranded DNA antibody level, increased urine protein level, increased Leydig cell tumor incidence, decreased sensitivity to skin irradiation, increased T cell derived lymphoma incidence, increased spleen weight, abnormal CD4-positive, alpha beta T cell morphology, enlarged lymph nodes, increased T cell proliferation, immune system phenotype, premature death, spleen hyperplasia, abnormal thymus physiology, enlarged cervical lymph nodes, increased anti-histone antibody level, increased anti-nuclear antigen antibody level, increased carcinoma incidence, increased memory T cell number, lymph node hyperplasia, increased IgG1 level, increased histiocytic sarcoma incidence, increased tumor incidence, kidney failure, increased lung carcinoma incidence
Affected Gene: Cdkn1a
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
