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Proper Citation: RRID:MGI:3610388
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal urine homeostasis, increased hepatocyte proliferation, jaundice, aminoaciduria, hepatic steatosis, enlarged liver, polyphagia, decreased body weight, cachexia, oroticaciduria, premature death, decreased body weight, decreased pancreas weight, decreased insulin secretion, small pancreatic islets, increased circulating glucose level, decreased pancreatic beta cell mass, abnormal urine calcium level, abnormal renal glucose reabsorption, abnormal circulating amino acid level, increased liver weight, abnormal stomach glandular epithelium morphology, increased circulating cholesterol level, absent subcutaneous adipose tissue, increased circulating bilirubin level, increased urine uric acid level, argininuria, decreased liver function, increased circulating aspartate transaminase level, prenatal lethality, incomplete penetrance, increased circulating ammonia level, increased circulating alanine transaminase level, postnatal growth retardation, decreased bone mineral density, increased urine phosphate level, increased urine glucose level, muscular atrophy, polyuria, decreased renal glomerular filtration rate, abnormal energy homeostasis, decreased creatinine clearance
Affected Gene: Hnf1a
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI