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Proper Citation: RRID:MGI:3582921
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased susceptibility to bacterial infection, small Peyer's patches, decreased follicular dendritic cell number, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased susceptibility to experimental autoimmune encephalomyelitis, abnormal spleen primary B follicle morphology, abnormal Peyer's patch morphology, abnormal metallophilic macrophage morphology, abnormal immune system physiology, abnormal spleen white pulp morphology, absent spleen germinal center, decreased susceptibility to endotoxin shock, abnormal lymph node primary follicle morphology, abnormal Peyer's patch follicle morphology, abnormal Peyer's patch morphology, abnormal spleen primary B follicle morphology, abnormal spleen marginal sinus morphology, abnormal spleen white pulp morphology, increased leukocyte cell number, decreased Peyer's patch number, increased susceptibility to bacterial infection
Affected Gene: Tnf
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
