Curator Dashboard

An Antibody supplier.

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• SciCrunch
• 14 years ago - by Anonymous

Archive of medical images of cancer accessible for public download. All images are stored in DICOM file format and organized as Collections, typically patients related by common disease (e.g. lung cancer), image modality (MRI, CT, etc) or research focus. Neuroimaging data sets include clinical outcomes, pathology, and genomics in addition to DICOM images. Submitting Data Proposals are welcomed.

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• SciCrunch
• 14 years ago - by Anonymous

An online science magazine with short science articles about everyday life and popular science book reviews. We like science. Thus, we have created this popular science online magazine to describe and explain scientific topics that confront us in our everyday life. These topics can be about natural phenomena, physics of sports, biology and life science, or the physics behind standard devices or common technologies. Additionally, we present and review popular science books. We address the general public in our science articles. Thus, our articles are short and explanations are easy to understand. We use a simple language to explain the science behind everyday topics so that it is fun to read. The texts are suitable for all age groups and also for non native English speakers and ESL classes. Submissions are welcome and after a review process, we would be happy to publish your contribution under your name. We also included a section in which readers can post questions. These posts inspire future articles. Science articles can be used as authentic sources in content-based instruction to teach English Language Learners (ELLs). For this purpose, I have created materials for teaching English in a scientific context. Select Science Niblets articles have been supplemented with relevant activities and additional authentic materials that encourage intercultural discussion and the use of the four receptive and productive language skills: reading, listening, writing and speaking. The theoretical and pedagogical framework that underlie the materials are explained in the teachers'' guide. The materials themselves consist of a lesson plan for the teacher and a learner worksheet that are printable pdf files.

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• SciCrunch
• 14 years ago - by Anonymous

Standards for communications between medical imaging devices, including handling, storing and transmitting information in medical imaging. It includes a file format definition and a network communication protocol.

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 11, 2022. Project for human epigenomic data from experimental pipelines built around next-generation sequencing technologies to map DNA methylation, histone modifications, chromatin accessibility and small RNA transcripts in stem cells and primary ex vivo tissues selected to represent normal counterparts of tissues and organ systems frequently involved in human disease. Consortium expects to deliver collection of normal epigenomes that will provide framework or reference for comparison and integration within broad array of future studies. Consortium is also committed to development, standardization and dissemination of protocols, reagents and analytical tools to enable research community to utilize, integrate and expand upon this body of data.

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• SciCrunch
• 15 years ago - by Anonymous

A dataset of a panel study of a representative sample of all neighborhoods and households in Los Angeles County, with poor neighborhoods and families with children oversampled, for investigating the social and economic determinants of health and race and ethnic disparities. The study follows neighborhoods over time, as well as children and families. Two waves have been conducted to date, in 2000-2001 (L.A.FANS 1) and again beginning in 2006 through early 2009 (L.A. FANS 2). L.A.FANS-2 will significantly enhance the utility of the L.A.FANS data for studies of adult health disparities by: 1) Replicating self-reported health measures from L.A.FANS-1 and collecting new self-reports on treatment, health behaviors, functional limitations, quality and quantity of sleep, anxiety, health status vignettes, and changes in health status since the first interview; 2) Collecting physiological markers of disease and health status, including diabetes, hypertension, obesity, lung function, immune function, and cardiovascular disease; and 3) Expanding the data collected on adults'' work conditions, stressful experiences, and social ties. Wherever possible, L.A.FANS uses well-tested questions or sections from national surveys, such as the Health and Retirement Study (HRS), Panel Study of Income Dynamics (PSID), National Longitudinal Surveys (NLS), and National Health Interview Survey (NHIS), and other urban surveys, such as the Project on Human Development in Chicago Neighborhoods, to facilitate comparisons. Data Availability: Public use data, study design, and questionnaire content from L.A.FANS are available for downloading. Researchers can also apply for a restricted use version of the L.A.FANS-1 data that contain considerable contextual and geographically-referenced information. Application procedures are described at the project Website. L.A.FANS-2 fieldwork was completed at the end of 2008. The PIs anticipate L.A.FANS-2 public use data will be released in summer 2009. * Dates of Study: 2000-2008 * Study Features: Longitudinal, Minority Oversamples, Anthropometric Measures, Biospecimens * Sample Size: ** 2000-1: 2,548 (L.A.FANS 1) ** 2006-8: ~3,600 (L.A.FANS 2) Link: * ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/00172

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• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 2, 2025. Database of chemicals and reactions inside of US patents (2001 - 2011). SCRIPDB provides the full original patent text, reactions and relationships described within any individual patent, in addition to the molecular files common to structural databases. The patent literature is a rich catalog of biologically relevant chemicals; many public and commercial molecular databases contain the structures disclosed in patent claims. However, patents are an equally rich source of metadata about bioactive molecules, including mechanism of action, disease class, homologous experimental series, structural alternatives, or the synthetic pathways used to produce molecules of interest. Unfortunately, this metadata is discarded when chemical structures are deposited separately in databases. SCRIPDB is a chemical structure database designed to make this metadata accessible. The SCRIPDB information is valuable in medical text mining, chemical image analysis, reaction extraction and in silico pharmaceutical lead optimization. SCRIPDB may be searched by exact chemical structure, substructure or molecular similarity and the results may be restricted to patents describing synthetic routes.

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• SciCrunch
• 15 years ago - by Anonymous

A dataset to advance the study of life-cycle interactions of biomedical and socioeconomic factors in the aging process. The EI project has assembled a variety of large datasets covering the life histories of approximately 39,616 white male volunteers (drawn from a random sample of 331 companies) who served in the Union Army (UA), and of about 6,000 African-American veterans from 51 randomly selected United States Colored Troops companies (USCT). Their military records were linked to pension and medical records that detailed the soldiers������?? health status and socioeconomic and family characteristics. Each soldier was searched for in the US decennial census for the years in which they were most likely to be found alive (1850, 1860, 1880, 1900, 1910). In addition, a sample consisting of 70,000 men examined for service in the Union Army between September 1864 and April 1865 has been assembled and linked only to census records. These records will be useful for life-cycle comparisons of those accepted and rejected for service. Military Data: The military service and wartime medical histories of the UA and USCT men were collected from the Union Army and United States Colored Troops military service records, carded medical records, and other wartime documents. Pension Data: Wherever possible, the UA and USCT samples have been linked to pension records, including surgeon''''s certificates. About 70% of men in the Union Army sample have a pension. These records provide the bulk of the socioeconomic and demographic information on these men from the late 1800s through the early 1900s, including family structure and employment information. In addition, the surgeon''''s certificates provide rich medical histories, with an average of 5 examinations per linked recruit for the UA, and about 2.5 exams per USCT recruit. Census Data: Both early and late-age familial and socioeconomic information is collected from the manuscript schedules of the federal censuses of 1850, 1860, 1870 (incomplete), 1880, 1900, and 1910. Data Availability: All of the datasets (Military Union Army; linked Census; Surgeon''''s Certificates; Examination Records, and supporting ecological and environmental variables) are publicly available from ICPSR. In addition, copies on CD-ROM may be obtained from the CPE, which also maintains an interactive Internet Data Archive and Documentation Library, which can be accessed on the Project Website. * Dates of Study: 1850-1910 * Study Features: Longitudinal, Minority Oversamples * Sample Size: ** Union Army: 35,747 ** Colored Troops: 6,187 ** Examination Sample: 70,800 ICPSR Link: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06836

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• SciCrunch
• 14 years ago - by Anonymous

A database of all mouse strains developed and/or housed in the Alexander Fleming Biomedical Sciences Research Center (BSRC), Greece, available to both internal and external researchers. The animal house unit provides its services to the various research groups of the BSCR as well as to external contractors in Europe and U.S.A. (pharmaceutical and biotechnology companies, leading hospitals, and academic institutions). The information provided includes: general information (i.e. internal Fleming contact, original mouse creator, allelic composition and MTA details), availability (i.e. available genetic background and strain state), allele & mutations (i.e. allele name and symbol and mutation type), publications and handling & genotyping instructions.

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• SciCrunch
• 15 years ago - by Anonymous

Database of helpful set of CreERT2 driver lines expressing in various regions of the developing and adult zebrafish. The lines have been generated via the insertion of a mCherry-T2A-CreERT2 in a gene trap approach or by using promoter fragments driving CreERT2. You can search the list of all transgenic lines or single entries by insertions (gene) or expression patterns (anatomy/region). In most cases the CreERT2 expression profile using in situ hybridization at 24 hpf and 48 hpf is shown, but also additional information (e.g. mCherry or CreERT2 expression at adult stages, transactivation of a Cre-dependent reporter line) is displayed. Currently, not all insertions have been mapped to a genomic location but the database will be regularly updated adding newly generated insertions and mapping information. Your help in improving and broadening the database by giving your opinion or knowledge of expression patterns is highly appreciated.

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• SciCrunch
• 15 years ago - by Anonymous

An integrated knowledgebase focused on protein termini, their formation by proteases and functional implications. It contains information about the processing and the processing state of proteins and functional implications thereof derived from research literature, contributions by the scientific community and biological databases. It lists more than 120,000 N- and C-termini and almost 10,000 cleavages. TopFIND is a resource for comprehensive coverage of protein N- and C-termini discovered by all available in silico, in vitro as well as in vivo methodologies. It makes use of existing knowledge by seamless integration of data from UniProt and MEROPS and provides access to new data from community submission and manual literature curating. It renders modifications of protein termini, such as acetylation and citrulination, easily accessible and searchable and provides the means to identify and analyse extend and distribution of terminal modifications across a protein. The data is presented to the user with a strong emphasis on the relation to curated background information and underlying evidence that led to the observation of a terminus, its modification or proteolytic cleavage. In brief the protein information, its domain structure, protein termini, terminus modifications and proteolytic processing of and by other proteins is listed. All information is accompanied by metadata like its original source, method of identification, confidence measurement or related publication. A positional cross correlation evaluation matches termini and cleavage sites with protein features (such as amino acid variants) and domains to highlight potential effects and dependencies in a unique way. Also, a network view of all proteins showing their functional dependency as protease, substrate or protease inhibitor tied in with protein interactions is provided for the easy evaluation of network wide effects. A powerful yet user friendly filtering mechanism allows the presented data to be filtered based on parameters like methodology used, in vivo relevance, confidence or data source (e.g. limited to a single laboratory or publication). This provides means to assess physiological relevant data and to deduce functional information and hypotheses relevant to the bench scientist. TopFIND PROVIDES: * Integration of protein termini with proteolytic processing and protein features * Displays proteases and substrates within their protease web including detailed evidence information * Fully supports the Human Proteome Project through search by chromosome location CONTRIBUTE * Submit your N- or C-termini datasets * Contribute information on protein cleavages * Provide detailed experimental description, sample information and raw data

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• SciCrunch
• 15 years ago - by Anonymous

STAP refinement of NMR Database is based the Statistical Torsion Angles Potentials to refine the NMR structure. It stored original solution NMR structures from the Protein Data Banks and our refined structures. Currently we carried out 2,405 refined NMR structure (until Sept 20, 2011). According to several studies, some nuclear magnetic resonance (NMR) structures are of lower quality, less reliable and less suitable for structural analysis than high-resolution X-ray crystallographic structures. STAP of NMR Refinement Database is a public database of 2405 refined NMR solution structures from the Protein Data Bank (PDB). A simulated annealing protocol was employed to obtain refined structures with target potentials, including the newly developed STAP. The refined database was extensively analyzed using various quality indicators from several assessment programs to determine the nuclear Overhauser effect (NOE) completeness, Ramachandran appearance, (1)-(2) rotamer normality, various parameters for protein stability and other indicators. Most quality indicators are improved in our protocol mainly due to the inclusion of the newly developed knowledge-based potentials. This database can be used by the NMR structure community for further development of research and validation tools, structure-related studies and modelling in many fields of research.

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• SciCrunch
• 15 years ago - by Anonymous

A dataset that provides researchers and policy makers information about issues affecting the elderly population in Puerto Rico: health status, housing arrangements, functional status, transfers, labor history, migration, income, childhood characteristics, health insurance, use of health services, marital history, mistreat, sexuality, etc. It investigates the characteristics of older adults (aged 60+) through an island-wide cross-sectional sample survey of target individuals and their surviving spouses. The sampling frame was constructed on the basis of an advance release of the 2000 US Census. The population for the study consists of the elderly population (60+) in households in Puerto Rico. The sample design used a multistage probabilistic sample by cluster. All elderly adults who lived in the selected households were eligible. If more than one person was in the target population, one 60+ adult was the target and one was the spouse. Respondents 80+ and males in couples who were both 80+ were oversampled. There were 4,293 targets aged 60+ and 1,444 spouses (all ages) in the first wave. Types of data include demographic; household composition; marital history; Cantrill Scale; mini-mental (designed to measure cognitive capacity of Spanish-speaking Latinos with low levels of education and to provide early indications of dementia); self-reported health status; diagnosed health conditions; childhood conditions; transfers; labor history; migration; housing; assets; Activities of Daily Living; Instrumental Activities of Daily Living; medicines; health insurance and use of health services; family structure; sexuality; anthropometric measures. Project innovations include: (1) the design and test of a new tool for assessing cognition among Spanish speaking elderly of low levels of education, (2) a symptoms section to assess the validity of selected self reported conditions, (3) a modification of the Cantrill''s Ladder Scale, (4) protocols for physical measurements to assess current, as well as past, conditions, and (5) the use of GIS and GPS in the fieldwork supervision and to geocoding the survey data. At this moment PREHCO has completed a second wave to become a longitudinal study. The questionnaire included questions regarding the changing conditions (health, residential, social and economic) of those individuals who responded the first questionnaire. The new questionnaire included novel components: vignettes for health status self-report, a new improved section on disability and dependency, and on labor force participation. We also expanded the section of anthropometry by adding a few measurements and physical efficiency tests. Those participants deceased or institutionalized were interviewed using a proxy. Data Availability: First and second wave data are available for public use through BADGIR, the online data archive at the University of Wisconsin-Madison, at: http://nesstar.ssc.wisc.edu/ * Dates of Study: 2002-2003, 2004-2006 * Study Features: Longitudinal, International, Minority Oversampling, Anthropometric measures * Sample Size: 5,336

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• SciCrunch
• 14 years ago - by Anonymous

Web portal that allows free access to supercomputing resources for large scale modeling and data processing. Portal facilitates access and use of National Science Foundation (NSF) High Performance Computing (HPC) resources by neuroscientists.

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• SciCrunch
• 15 years ago - by Anonymous

An MRI data set that demonstrates the utility of a mega-analytic approach by identifying the effects of age and gender on the resting-state networks (RSNs) of 603 healthy adolescents and adults (mean age: 23.4 years, range: 12-71 years). Data were collected on the same scanner, preprocessed using an automated analysis pipeline based in SPM, and studied using group independent component analysis. RSNs were identified and evaluated in terms of three primary outcome measures: time course spectral power, spatial map intensity, and functional network connectivity. Results revealed robust effects of age on all three outcome measures, largely indicating decreases in network coherence and connectivity with increasing age. Gender effects were of smaller magnitude but suggested stronger intra-network connectivity in females and more inter-network connectivity in males, particularly with regard to sensorimotor networks. These findings, along with the analysis approach and statistical framework described, provide a useful baseline for future investigations of brain networks in health and disease.

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• SciCrunch
• 15 years ago - by Anonymous

ELK is an ontology reasoner with the goal of supporting the OWL 2 EL profile. ELK is a specialized reasoner for the lightweight ontology language OWL EL. The practical utility of ELK is in its combination of high performance and comprehensive support for language features. At its core, ELK employs a consequence-based reasoning engine that can take advantage of multi-core and multi-processor systems. A modular architecture allows ELK to be used as a stand-alone application, Protege plug-in, or programming library (either with or without the OWL API).

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• SciCrunch
• 15 years ago - by Anonymous

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU.

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• SciCrunch
• 15 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2025. Human protein knowledge platform. Knowledge platform for human proteins selects and filters high throughput data pertinent to human proteins from UniProtKB. Extends UniProtKB/Swiss-Prot annotations for human proteins to include several new data types.

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• SciCrunch
• 15 years ago - by Anonymous

A Java-based, Microarray or Genechip data analysis system.

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• SciCrunch
• 13 years ago - by Anonymous

A collection of data that describes and identifies predictors of mortality, hospitalization, and placement in long-term care facilities and investigates risk factors for chronic diseases and loss of functioning. The EPESE project consisted of baseline and annual follow-up surveys on approximately 14,000 noninstitutionalized persons aged 65 and older in four geographically-defined communities: East Boston, Massachusetts; Iowa and Washington counties, Iowa; New Haven, Connecticut (started in 1982-1983); and a five-county-wide region in north-central North Carolina (started in 1986). Half of the participants in the North Carolina EPESE are African-American. The baseline data cover demographic characteristics (age, sex, race, height, weight, income, education, marital status, number of children, employment, and religion); social and physical functioning; chronic conditions; related health problems; health habits; self-reported use of dental, hospital, and nursing home services. More detailed descriptions of the Iowa and North Carolina surveys follow in this document (Iowa 65+ Rural Health Study and PHSE Ten-Year Follow-up of North Carolina EPESE). Data Availability: Data from the baseline and the first 6 years of follow-up are available as ICPSR Study No. 9915. Information from death certificates obtained for deaths occurring in the first 6 years of follow-up is also available. * Dates of Study: 1981-1993 * Study Features: Longitudinal, Minority Oversamples, Anthropometric Measures * Sample Size: ** 1981: 14,458 (Baseline) ** 1982: 14,070 (First follow-up) ** 1983: 13,382 (Second follow-up) ** 1984: 12,381 (Third follow-up) ** 1985: 11,657 (Fourth follow-up) ** 1986: 10,998 (Fifth follow-up) ** 1987: 9,998 (Sixth follow-up) Link * ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/09915

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• SciCrunch
• 14 years ago - by Anonymous