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CBS houses a core facility with a transmission electron microscope (TEM) and several scanning electron microscopes. The SEMs are part of ongoing research that will lead to a three-dimensional electron microscopy facility, to image neural circuits with the highest possible resolution.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Complex protein mixture analysis service, Project consultation service, Data analysis service, Protein identification service, Posttranslational modification site determination service, N-terminal Edman Sequence Analysis Service, C-terminal sequence analysis service, De novo sequence analysis service, Quantitative proteomics service, Labeled quantitative proteomics - SILAC, Labeled quantitative proteomics - ICAT service, Labeled quantitative proteomics - iTRAQ service, Labeled quantitative proteomics - AQUA service, Intact molecular weight determination service, Low resolution GC/MS service, Low resolution GC/MS/MS service, Exact mass MS & MS/MS electrospray for structural elucidation service. The FAS Center for Systems Biology Mass Spectrometry and Proteomics Resource Laboratory provides mass spectrometry and strategic consulting in Proteomics and Small Molecule analysis for Life Science and Chemistry researchers as well as others worldwide. This resource brings together the state-of-the-art expertise and instrumentation of the Microchemistry and Proteomics, CCB Mass Spectrometry, and Bauer Center Core laboratories, leveraging our breadth of experience to provide the best possible support for your research.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides service for paraffin embedding, sectioning, staining, and frozen sectioning; shared equipment and service for confocal, widefield, photodocumentation, electron microscopy, and digital image processing; and an immunostaining service.

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• SciCrunch
• 13 years ago - by Anonymous

Self-training Algorithm for Splice Junction Detection using RNA-seq.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Use of instruments service, Training service. The Harvard Center for Biological Imaging (HCBI) has been created to foster collaborative research in the most state-of-the-art facility available. To do this, we have set up a unique partnership with Carl Zeiss International in which our microscopy systems are continually replaced every 2-3 years ensuring we always have the most up-to-date equipment possible. The facility is open 24 hours/day, 7 days/week and access to the facility is open to all Harvard investigators as well as to affiliates and investigators from collaborating institutions.

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• SciCrunch
• 13 years ago - by Anonymous

Center for Nanoscale Systems facility dealing with FIB, XPS, AFM, Optical Microscopy and Spectroscopy, Biomaterials, Soft Lithography, Microfluidics, Nano Particles, Chemical Nanotechnology, etc.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Nanofabrication cleanroom and instrumentation access, instrument training, staff assistance. The Center for Nanoscale Systems'' Nanofabrication Facility (CNS-NF), offers resource and staff support for fabricating and characterizing nanoscale devices and structures. The facility currently operates the 10,000 sq.ft. LISE Cleanroom with leading-edge equipment capable of electron-beam and optical lithography, physical and chemical vapor deposition, dry and wet processing, metrology, and device characterization.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Access/training service. <BR/> <BR/>Lab performs services related to paleontology, paleopathology, and paleohistology. This core houses significant expertise in processing and analysis of mineralized tissues.

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• SciCrunch
• 13 years ago - by Anonymous

The National Nanotechnology Infrastructure Network?s computational activity (NNIN/C) is the computational counterpart of the NNIN experimental initiative. Like the NNIN experimental program, NNIN/C is a multi-university initiative, funded by the National Science Foundation (NSF). Harvard University serves as the coordinating hub of NNIN/C, the object of which is to establish a national computing resource that provides hardware resources and simulation tools dedicated to nanoscience research for the academic and industrial research communities. Strong technical and scientific support is provided by staff experts so that the tools and resources can benefit interdisciplinary research. The software tools include commercial software packages for design, characterization and analysis of nanometer scale devices as well as some of the latest academic advances in nanoscale modeling and simulation software. The goals and strategies of NNIN/C are: * Assemble and create a wide suite of robust software that addresses critical issues related to the physical, chemical, and biological properties of artificial and natural nanoscale structures. * Maintain and, where necessary, modify these simulations to address a broad range of research problems. * Provide strong technical support and thorough instruction on the software tools so that even novice users can rapidly develop solutions to their own unique research problems. * Provide web-based graphical user interfaces (GUIs) for user-friendly access to simulation tools as well as web-based resources for instruction and feedback to the community of researchers employing the same tools

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• SciCrunch
• 13 years ago - by Anonymous

Center for Nanoscale Systems facility dealing with SEM, TEM, ESEM, sample prep etc.

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• SciCrunch
• 13 years ago - by Anonymous

Provided core services include Sanger DNA Sequencing, Next Generation DNA Sequencing (Four Illumina MiSeqs, four Illumina NextSeq 500s and one Illumina NovaSeq 6000),Next Generation Automated Library Sample Prep (Perkin Elmer Sciclone Genomic, ChIP, RNAseq and other methods), Single Cell DNA and RNA-Seq (10X Genomics Chromium), Bioanalyzer Analysis DNA and RNA (Two Agilent 2100 BioAnalyzers and two Agilent 2200 TapeStations), Qiagen Qiacube Automated DNA / RNA Prep (single to multiple samples), Oligonucleotide Ordering (IDT Portal), Reagents and Supplies Ordering (multiple vendors / products). Facility web based Laboratory Information Management System (LIMS) provides users with access to order services and supplies as well as retrieve data and review and pay invoices all online.

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• SciCrunch
• 13 years ago - by Anonymous

Core for data driven projects related to basic, clinical and translational research, with a particular emphasis on diabetes. Aims to ensure that researchers take advantage of the most modern and robust methods available in the field of Bioinformatics and Biostatistics.

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• SciCrunch
• 13 years ago - by Anonymous

An application for discovering potential splice junctions in high throughput sequencing (HTS) data.

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• SciCrunch
• 13 years ago - by Anonymous

Flow cytometry access facility. All new users must be trained by the facility manager over two orientation sessions and be approved to use the equipment in the facility. All users must obtain the financial approval from their PI and financial manager. Please submit a PO number or the Harvard billing code prior to the first use of the facility.

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• SciCrunch
• 13 years ago - by Anonymous

The Exposure and Environmental Analyzes Service provides exposure assessment equipment, design of experimental apparatus, laboratory analyzes of environmental and biological samples, support for methods development and pilot data, as well as training for researchers and students. The service maintains facilities such as clean rooms and exposure chambers. Specific services are provided by the four affiliated laboratories.

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• SciCrunch
• 13 years ago - by Anonymous

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• SciCrunch
• 17 years ago - submitted by Stephen Larson

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core provides intellectual guidance for quantitative aspects of the design and analysis of center studies and expertise in biostatistical methods, environmental risk assessment, Geographic Information System (GIS) , spatial statistics, molecular biology, bioinformatics and statistical genetics. Core runs a regular seminar series and often sponsors short courses on specialized topics of interest to the community.

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• SciCrunch
• 13 years ago - by Anonymous

The EM Lab supports study relating to aerobiology. The laboratory has the capability to generate, sample, and analyze fungal, bacterial, and viral microbes.

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• SciCrunch
• 13 years ago - by Anonymous

The aims of the EGS are: to assist Center investigators in preparing genomic DNA from blood/buccal swabs collected in their human population studies. This activity involves assistance in the proper collection, extraction, concentration, quality testing and hand or robotic plating for candidate gene and even Genome-Wide studies of gene-environment interaction; to assist Center investigators in creating a genomic DNA biorepository for DNA for genotyping and for epigenetics studies; to assist investigators in obtaining efficient genotyping and epigenetic services either in-house or through partner organizations in the Harvard system; and to assist Center investigators in selection of SNP''s, haplotypes, genotyping platforms and for environmental genetic and epigenetic studies of human populations.

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• SciCrunch
• 13 years ago - by Anonymous

Electron microscope access facility. All new users must be trained and approved by the facility manager to use the equipment in the facility and obtain the financial approval from their PI and financial manager. Please submit a PO number or the Harvard billing code prior to the first use of the facility. Approved users can sign up with the facility manager.

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• SciCrunch
• 13 years ago - by Anonymous