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University of Lyon, located in Lyon and Saint-Étienne, France, is a center for higher education and research comprising 11 members and 24 associated institutions.
The Eicosanoid Core Laboratory facility employs mass spectrometry to quantify lipid oxidation products produced in a variety of vascular (and other) disorders including prostaglandins, leukotrienes, isoprostanes, and their urinary metabolites.
This core has several components. The DNA bank receives specimens from various studies, extracts DNA, and provides storage. Quality control, organization, and efficiency are critical. Genotyping services provide the necessary speed, efficiency, and accuracy to perform genomic screens (with standard markers) in as little time as possible.
BioVU is a research resource providing a View into biology at the level of DNA and other important macromolecules. BioVU has two major components. The first is a repository of DNA samples (extracted from discarded blood samples) that are coded solely by a Research Unique Identifier (RUI) derived from the Medical Record Number (MRN) using a one-way hash function. This is a computer algorithm that creates a transformation of each MRN such that the resulting RUI (which is in this instance is a 512 byte identifier) is unique, and has the property that it is not possible to infer or compute the MRN that generated it. As of early 2009, over 50,000 DNA samples were in the biobank, with new samples being added at the rate of approximately 700 per week.
Core facility that provides the following services: Biospecimen acquisition. The Cooperative Human Tissue Network- Western Division at Vanderbilt University Medical Center is one of six institutions throughout the country funded by the National Cancer Institutes to procure and distribute remnant human tissues to biomedical researchers throughout the United States and Canada. CHTN operates through a shared networking system which allows investigators greater access to available research specimens. CHTN offers a variety of preparation and preservation techniques to ensure investigators are receiving the quality specimens needed for research. Remnant tissues are obtained from surgical resections and autopsies and are procured to the specifications of the investigator.
THIS RESOURCE IS NO LONGER IN SERVCE, documented January 25, 2019. Core provides software and hardware support for computing activities related to genetics and biology, as well as statistical analysis for human genetics data generated from both microsatellite markers and SNPs. Bioinformatics support, resources, and expertise are available in storing and managing demographic, clinical, genotypic, microarray, proteomic and biospecimen data.
The primary mission of the Clinical Trials Shared Resource (CTSR), as identified in the Cancer Center Support Grant (CCSG), is to assist Cancer Center investigators develop, activate and complete scientifically-meritorious clinical trials in an efficient, cost-effective and technically-sound manner.
An Core facility
The purpose of the Vanderbilt Clinical Research Center is to provide the resources needed by clinical and translational investigators to carry out their research in an environment optimized for safety, comfort and convenience of the patient or volunteer, with the facilities and expertise to provide the most advantageous milieu in which to address the investigator''s experimental requirements. This includes outpatient space, inpatient beds, laboratories, equipment and supplies for clinical research by the faculty of Vanderbilt University, Meharry Medical College, and their collaborating investigators. The use of the center is justified on the basis of the quality and significance of the research and the special need for the Center''s facilities.
The Chemical Synthesis Core was established within the Vanderbilt Institute of Chemical Biology with the goal of supporting the organic and medicinal chemistry needs of investigators. The primary focus of the core is to facilitate biology-orientated projects within the medical center and the university by assisting with the chemistry aspect of the project. The core works independently or in collaboration with the VICB High Throughput Screening Center on the synthesis of literature-cited compounds (including patented ones) as well as full scale lead optimization of a compound.
Scientific agency of the United States government. The scientists of the USGS study the landscape of the United States, its natural resources, and the natural hazards that threaten it. The organization's work spans the disciplines of biology, geography, geology, and hydrology.
Ontology that represents the structure that BioPortal uses to represent all of its metadata (ontology details, mappings, notes, reviews, views)
The Center for Molecular Neuroscience (CMN) at the Vanderbilt University School of Medicine supports interdisciplinary research and training in cellular and molecular neurobiology. Internationally recognized faculty approach the intricacies of neurogenesis, neural signaling and synaptic plasticity using leading-edge techniques in state-of-the-art research facilities.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides any Vanderbilt researcher with access to imaging equipment and expert technical support for microscopy and analysis of tissue and cellular physiology.
The primary focus of the Core Lab is to build and properly maintain biospecimen collections in the repository.
The Biostatistics Collaboration Center at Vanderbilt (BCC) is a university sponsored core resource whose goal is to provide for, enhance, and/or facilitate statistical collaborations involving the design, conduct, analysis or publication of biomedical research at the university.
Core facility that provides the following services: Biospecimen processing and analysis, DNA/RNA extraction and banking, Genotyping. The Molecular Epidemiology Laboratory provides genotyping and other lab services for large-scale studies to Vanderbilt investigators related to biological specimen collection and storage, as well as biomarker and genetic marker assays.
The CSB maintains a variety of instruments for studying the conformation and stability of macromolecules and for measuring the affinity and thermodynamics of biomolecular interactions.
Core facility that provides the following services: Experiment design assistance. The principal mission of the Biomolecular NMR Center is to provide instrumentation for, and aid in obtaining data on the structure and dynamics of biological macromolecules. The Facility offers state-of-the-art instrumentation, training, software and assistance in designing experiments
The Automation and Informatics Core is responsible for integrating automation and instrumentation with downstream data handling and reporting. Duties of the group include: a) maintaining the laboratory computer network and technology infrastructure, including maintaining network security, performing data backups, managing data access, and trouble-shooting b) database management and information processing, including management of the Laboratory Information Management System (LIMS) c) performing systems analysis and programming as needed for instrument interfaces and integration, as well as extracting, reformatting, uploading, aggregating and/or analyzing data gathered in the course of HTS experiments d) maintaining the automation and robotics, including configuration, calibration, implementation, and trouble-shooting, to ensure maximum uptime/availability and utmost precision and accuracy e) assisting laboratory and scientific personnel with all their informatics needs, including overseeing data exchanges with our collaborators.