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Core facility that provides the following services: DNA extraction from blood and cell lines. <BR/> <BR/>This facility provides processing of cell lines, human blood and tissue samples for DNA, plasma and buffy coat storage and for initiation of lymphoblast and fibroblast cell lines in furtherance of the CHGR mission to promote the use of genetic strategies in basic and clinical research.

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• SciCrunch
• 13 years ago - by Anonymous

The Clinical Genetic Research Facility (CGRF) offers clinical investigators a convenient, modern research-dedicated facility for outpatient studies involving genetics. Our outpatient exam rooms and phlebotomy rooms are fully equipped and offer investigators an experienced medical assistant to facilitate the visit. Since the CGRF?s primary mission is to support and promote genetic clinical research, the facility?s investigators performing genetic studies supported by non-commercial sponsors are given priority. The CGRF also considers genetic studies sponsored by industry, as well as studies without a genetic component, on a space-available basis.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Breeding pair service, Mouse Phenotyping Services. <BR/> <BR/>This resource provides to MGH investigators a local source of breeding pairs of the 22 chromosome substitution strains (CSS)* of mice and access to basic phenotyping equipment for mapping of simple or complex traits, to promote the use of genetic mouse-based strategies in basic and clinical research. The CSS Resource comprises 22 mouse lines, each homozygous for a single A/J chromosome (Chr 1-19, X or Y and mitochondria) on a genetic background that is otherwise C57BL/J that were generated by Dr. Joseph Nadeau (Case Western Reserve University) and his colleagues. The CSS mice are available from The Jackson Laboratories. However, to save time and money, the MGH CSS Resource maintains CSS breeding colonies that are housed in the Simches-8 barrier facility, adjacent to a procedure room that will have equipment for basic standardized phenotyping, including behavioral and metabolic measurements.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: DNA sequencing service, High volume DNA sequencing, Plasmid verification and primer walking service, PCR purification service, Microsatellite analysis. <BR/> <BR/>The DNA Sequencing Core at the Massachusetts General Hospital functions both as a small-scale sequencing facility and a high-throughput center for large-scale sequencing projects.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: 96-well plasmid preparation service. <BR/> <BR/>The Center for Computational and Integrative Biology (CCIB) Automation Core provides the greater Partners research community with high-throughput automation services as well as special automation project design and implementation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 13 years ago - by Anonymous

The Biostatistics Center provides support to MGH investigators, as well as serving as a Coordinating Center for several NIH-supported projects. The Center''s staff includes biostatisticians, physicians, research nurses, data managers, project managers, research assistants, and computing staff.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6th,2022. The Oregon Alzheimer?s Disease Center?s (OADC) Clinical Core program, directed by Dr. Jeffrey Kaye, performs longitudinal studies of the natural history of brain aging and Alzheimer''s disease in patients and healthy control volunteers. These studies which are performed through standardized neurological, neuro-psychological, and brain-imaging assessments are carried out in the Alzheimer''s Disease and Memory Assessment Clinics as well as through community-based assessments conducted in the homes of study volunteers. The Layton Center Neuroimaging Lab conducts brain-imaging MRI brain scans to assist in diagnosis of brain disease. Typically, MRI images are taken from three different planes. These planes are known as the coronal plane, sagittal plane and the axial plane. Each series of MRI images is named after the plane from which they were obtained. The Clinical Core?s research is focused on preclinical and early Alzheimer?s disease (AD) yet is also poised to participate in other relevant new research as it arises. The OADC Clinical Core recruits, assesses and follows individuals from population groups at high risk for dementia such as: the healthy ?oldest old?, subjects with family history of AD, and subjects with Mild Cognitive Impairment (MCI). Research with underserved populations The Oregon Alzheimer?s Disease Center also maintains two Satellite programs to enhance understanding of underserved populations: The Klamath Exceptional Aging Project (KEAP) is a community-based study of brain aging being conducted in Klamath Falls. The African American Dementia and Aging Project (AADAPt) s a Portland-based cohort of 100 African American seniors.

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• SciCrunch
• 13 years ago - by Anonymous

In cooperation with the Data and Clinical Cores at the Layton Center, the Biomarkers and Genetics Core generates and maintains biomarker data for select biomarkers which have established roles in the characterization of subjects with or at risk of dementia. Biological markers of brain aging, dementia risk, and neurodegeneration have the potential to accelerate the identification of disease mechanisms and treatment strategies. Biomarkers may include genes, proteins, or other metabolites, and may be identified in DNA, cerebrospinal fluid (CSF), or plasma. Apolipoprotein E (APOE) genotype is generated for all research subjects. Sub-groups of subjects have other types of biomarker data. Many subjects have had genome-wide SNP data generated. In order to foster collaborative research as well as expand resources and expertise, samples (DNA, CSF, and plasma) and data are distributed to qualified investigators worldwide. Most of these researchers are pursuing the causes and modifiers of dementia. Data and samples are collected from well characterized research subjects including the healthy elderly and dementia patients.

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• SciCrunch
• 13 years ago - by Anonymous

Software tool that calculates features of meta-stable RNA secondary structure target sites.

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• SciCrunch
• 13 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 5th,2022. The Education and Information Core of the Layton Aging & Alzheimer?s Disease Center develops and carries out a wide range of educational programs to: * Increase public awareness and understanding of Alzheimer''s Disease research, * Aid in the recruitment of subjects for research studies, and * Improve care and quality of life for persons with dementia and support their family caregivers. Our educational activities include: * Training for health care professionals which include seminars and lectures and we also provide ?hands-on? experiences for medical students, * Community education on Alzheimer''s disease and related dementia disorders, * Workshops on doctor ? patient communication for families and caregivers, * Collaboration with community organizations and groups to promote awareness of the disease and publicize research activities, a particular focus is underserved populations including rural communities and minority groups, * Collaboration with other organizations that serve patients and families, e.g., the Alzheimer?s Association and other state and local agencies that serve the elderly and the loved ones who care for them, and * Distribution of printed material that provides topical information on a variety of subjects related to Alzheimer?s disease and dementia and how best to provide quality of life to those with the disease. * A newsletter, Aging & Alzheimer''s Update, which is published twice per year. The Education Core administers the Oregon Income Tax Check-off Alzheimer''s Research Fund in collaboration with The Oregon Partnership for Alzheimer''s Research, a community advisory committee.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Microscopy, Imaging, and Analysis, Routine Histopathology, Specialized Histopathology. The purpose of this core laboratory is to assist investigators requiring detection, imaging, and morphometric analysis of gene and protein expression in any type of cell and tissue. Services, expertise and state-of -the-art biomedical imaging services will be provided with the hope of broadening and streamlining all morphological research.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Probe hybridization, Microarray data analysis. In December 2000, the LSUHSC Program in Gene Therapy in conjunction with the Louisiana Gene Therapy Research Consortium created the Microarray Core to cater to the growing needs of investigators who wanted to perform expression studies. Since that time, our core has helped researchers from around the world process over 3000 samples, resulting in numerous peer-reviewed scientific publications.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Automated DNA sequencing, Quantitative real-time PCR, Genotyping service, Liquid handling service. The Genomics Core Facility is a core resource of LSU Health Science Center, sponsored jointly by the Cancer Center and Genetics Center. The Facility is committed to providing quality service by fulfilling the needs of the research community in a consistently rapid, dependable, and economical fashion. Services include automated DNA sequencing, using state-of-the-art instrumentation (ABI PRISM 3130XL Genetic Analyzers) and the latest protocols to ensure high quality results at reseasonable prices. The Facility also houses an ABI Prism 7900 HT (a high through-put real-time PCR system) and a Biomek2000 liquid handling robot.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: FACS service, Flow cytometry analysis service, Data archival. The Cell Analysis & Immunology Core Facility is a customer oriented service dedicated to supporting the research needs of the investigators of the Louisiana Cancer Research Consortium (LCRC). It provides state-of-art instrumentation and expertise for addressing experimental issues related to single cells, nuclei and chromosomes. In addition to instrumentation, the Facility intends to collaborate with the investigators and contribute to all aspects of the research process. This includes consultation in experimental design, technical assistance in the operation of instruments, trouble shooting, data analysis and storage, interpretation of results and preparation and production of presentation graphics. The Facility is also communicating with investigators in other institutions and is devoted to introducing and developing new applications on our flow cytometers. In this way, investigators are provided with unlimited possibilities to answer questions regarding nature and function of cells by flow cytometry.

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• SciCrunch
• 13 years ago - by Anonymous

A software application for inferring expression levels of individual transcripts from sequencing (RNA-Seq) data and estimating differential expression (DE) between conditions.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Colony Forming Unit (CFU) Assay, Differentiation assays. Core purpose: To propagate, expand and supply high quality samples of normal mesenchymal stem cells (MSCs) from in vitro cultures with appropriate quality control assurances for use by LCRC investigators who are studying any aspect of MSCs in relationship to cancer.

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• SciCrunch
• 13 years ago - by Anonymous

The JHS is the largest single-site longitudinal, population-based, cohort study of 5,302 persons initiated in the fall of 2000 to prospectively investigate the determinants of CVD among African Americans in the Jackson, MS metropolitan statistical area. The JHS investigates the various genotype and phenotype factors that affect high blood pressure, heart disease, strokes, diabetes and other important diseases in African Americans. The primary objective of the Jackson Heart Study is to investigate the causes of cardiovascular disease (CVD) in African Americans to learn how to best prevent this group of diseases in the future. More specific objectives include: 1. Identification of factors, which influence the development, and worsening of CVD in African Americans, with an emphasis on manifestations related to high blood pressure (such as remodeling of the left ventricle of the heart, coronary artery disease, heart failure, stroke and disorders affecting the blood vessels of the kidney). 2. Building research capabilities in minority institutions at the undergraduate and graduate level by developing partnerships between minority and majority institutions and enhancing participation of minority investigators in large-scale epidemiologic studies. 3. Attracting minority students to and preparing them for careers in health sciences.

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• SciCrunch
• 13 years ago - by Anonymous

Research university that is located in Rome, Italy.

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• SciCrunch
• 16 years ago - submitted by Stephen Larson

Core facility that provides the following services: DNA Synthesis Service. <BR/> <BR/>The DNA Synthesis Lab serves the research community with custom oligonucleotides. The lab is capable of high-throughput standard, degenerate and modified oligo synthesis.

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• SciCrunch
• 13 years ago - by Anonymous

Core facility that provides the following services: Equipment access. Jackson State University Visualization Laboratory is part of the Trent Lott Geospatial and Visualization Research Center (TLGVRC). It is a research laboratory specializing in virtual reality and real-time interactive computer graphics. The mission of the visualization laboratory is to ensure highly advanced technical and theoretical visualization support to scientific research. Our goal is to provide a well-integrated and diverse scientific visualization knowledge and tools to the students, staff, and faculty.

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• SciCrunch
• 13 years ago - by Anonymous