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Biomolecular Research Core Facility (BRCF) has collection of instrumentation for characterization of biomolecules and their role in variety of processes. Instrumentation is accessible to internal and external customers. Available instrumentation focuses on mass spec, histology, imaging, and protein biochemistry.
Core provides equipment and infrastructure required to conduct advanced genomics research. Provides access to DNA sequencing, traditional Sanger sequencing and genotyping, and additional equipment services for functional genomic assays and mapping. Provides robotics and instrumentation to facilitate the handling of large numbers of samples, as well as many advanced sequencing and sequencing support applications.
NIDA IRP Confocal and Electron Microscopy Core serves NIDA-IRP researchers by providing access to confocal and electron microscopic technologies to characterize cellular and ultrastructural properties of organelles, tissue culture and brain tissue. Provides expertise, consultations and training in adaptation and execution of confocal and electron microscopic techniques and procedures.
Software application for accurate and rapid prediction of IAV subtypes and host source.
Electronic von Frey system for rodents. Used for touch sensitivity in unrestrained animals. The scientist gradually increases the force applied to the animal paw, until the peak detector scores the animal paw withdrawal (or the user scores it manually with the included pedal).
Cogentech's CGT lab is offering its diagnostic services for Hereditary Tumors (Cancer Risk) and for Personalized Medicine (Therapy) to clinicians, laboratories and hospitals.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 8th,2025. Cogentech's DNA Sanger Sequencing (DSS) Core Facility offers standard DNA sequencing and assistance for projects using on Sanger sequencing. We also offer the possibility to use fragment analysis for various applications, providing assistance in the pre-and post-analytical phase. The laboratory is ISO9001 certified.
Cogentech's Integrated Genomics Core Facility (IGU) consists of units: Molecular Biology and Sequencing, Histopathology and Bioinformatics. Molecular Biology group provides expertise in various fields of application: nucleic acid extraction from different matrices, ddPCR and various types of sequencing (customised gene panels, Lowpass WGS, WES, WGS, total RNA-Seq, mRNA Seq, TCR-Seq, 16S Metagenomic Seq, ATAC-Seq, genome-wide methylation profiling). Bioinformatics unit provides pipelines for analysis of data produced by all sequencing workflows. In addition, it provides its expertise for implementation and development of customised pipelines. Histopathology unit offers services for slide preparation and staining, image digitisation and laser-capture microdissection. The laboratory is ISO9001 certified.
Cogentech's Proteomics and Metabolomics Core Facility provides infrastructure for identification, characterization and quantification of proteins, metabolites and lipids.Offers several instrumental platforms for separation of those molecules. Proteomics, metabolomics and lipidomics analysis rely on mass spectrometry coupled with liquid chromatography.
Cogentech's Biological Research Facility (BRF) provides animal facility in which laboratory mice are maintained and bred for different research programs. The laboratory is ISO9001 certified.
Cogentech's Genomic Core Facility (GU) provides professional support for workflow of research projects, from counseling on experimental design to functional interpretation of results. Support includes identification of the most suitable methodology to achieve the experimental aim, quality control of nucleic acid, generation of indexed fragment library, sequencing according to experimental needs and bioinformatic support for selected applications. Customized protocols can be set-up as well. Sequencing data are delivered using a password protected user-friendly web interface. The laboratory is ISO9001 certified.
Cogentech's Histopathology (HP) Core Facility provides services including consultation, tissue trimming and embedding, cutting, staining, photographic documentation for the evaluation and characterization of normal and pathological tissues. Provides Optimization of protocols for new stains or biological specimen.The laboratory is ISO9001 certified.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 8th,2025. ogentech's Quantitative PCR (QPCR) Core Facility provides services including project design, assay selection and development, data analysis for quantitative analysis of any specific target sequence for gene expression, copy number variation or variant analysis, in low and high-throughput mode. Provides analysis using both Real Time PCR and digital PCR. Special protocols for small amounts of starting material have been implemented. The laboratory is ISO9001 certified.
Core supports basic and clinical research by providing histological and molecular expertise, technical support and consultation to research investigators. Provides histological, molecular and consultation services. Services are performed by American Society of Clinical Pathology certified histologists with expertise in routine histology, whole slide scanning, image and digital analysis, pathology services, immunohistochemistry, tissue microarray, bone histomorphometry, Visium preparations and RNAscope single and co-detection assays.
Core provides researchers with genetic tools, including shRNA, ORF and CRISPR for studying and annotating gene functions in cell-based assays. FGC personnel provides research support for investigators who are interested in genetic screens.
Open-source web application created for easy access, collaboration, and sharing of datasets through rich metadata search, filter, sort, and direct viewing in common industry applications or in our web-based 3D Volume Viewer.
Software semiempirical extended tight-binding program package. Provides userfriendly interface for performing geometry optimizations, vibrational frequency calculations, and Molecular Dynamics simulations.
Software application as quantum chemical based program that enables users to calculate mass spectra using Born-Oppenheimer Molecular Dynamics. Quantum mechanic mass spectrometry calculation program.
Software Monte Carlo tool for particle simulation. Used for simulation of medical applications of ionizing radiation with the Monte Carlo method. Allows to assemble and control library of simulation objects (geometry components, particle sources, scorers, etc.) with no need to write C++ code and without knowledge of underlying Geant4 Simulation Toolkit.
Software package provides several functions and parameters for simulating genetic variations. Benchmarking variation simulator mimicking human variation spectrum.