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THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Oligonucleotide synthesis service, Automated DNA sequencing, Genotyping analysis service, Analysis of DNA, RNA or proteins, Microarray service. The long-term goal of the Center for Genomics in Health Disparities and Rare Diseases (CGHDRD) is to provide the critical environment that will enable high quality translational and biomedical research in pharmacogenomics, human genetics and genomics, molecular biology. We aim to develop and strengthen a collaborative research environment by providing research infrastructure that supports the focal areas of research at the University of Puerto Rico Medical Sciences Campus (UPR-MSC), which encompass common diseases such as cancer, neurological and cardiovascular disorders as well as rare disorders, by improving the human and physical resources. The Center focuses these initiatives on externally funded, interdisciplinary, collaborative projects which enhance the quality of translational, biomedical and clinical research at the Medical Sciences Campus linked to health disparities and rare disorders in Puerto Rico and nationally. Collaborations with researchers at institutions outside of Puerto Rico or other RCMI institutions, as well as other academic units in the island and in the UPR system are encouraged. The Center provides the necessary expertise to apply high throughput genotyping, expression profiling and sequencing technologies at the UPR-MSC. Specialized technical staff trains researchers at different levels of their scientific careers in supported technologies. Novel DNA and RNA isolation methodologies are applied to a diverse group of organisms and biological samples for nucleic acids sequence analysis in general.
The CDIR serves as the focal point for drug information, research, education, and service within the University of Puerto Rico - School of Pharmacy. The CDIR is the first academic-based research center in Puerto Rico solely dedicated to provide answers to drug related information inquires, health service research support consultations, and the development, implementation and evaluation of pharmacy educational programs. The mission of the CDIR is to improve drug therapy in Puerto Rico through drug information services, and educational, clinical and novel research initiatives.
Cayo Santiago is one of the world''s most renowned field sites for short term and longitudinal non-human primate studies. Its unique research value consists of:a stable and minimally disrupted long-term population management policy which allows investigators to plan and conduct longitudinal studies, an extensive and detailed computerized demographic database on the colony that provides information on individuals dating back to 1957, and DNA fingerprinting which is applied to confirm maternal and paternal relatedness of individuals.
THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core aims to enhance biomedical research in Puerto Rico by providing resources for research, education and training. These resources will work to advance these specific aims: 1. enhance biomedical research in PR by providing researchers with the bioinformatics tools and technical support they require to perform cutting-edge biomedical research; 2. enhance the computational biology research environment in Puerto Rico by establishing research collaborations with biomedical, computational and mathematics researchers; 3. enhance multidisciplinary research by developing new courses and educational materials in computational biology, statistics and bioinformatics in collaboration with research faculty and the Science and Technology Competency Enhancement (STCE) Core; 4. enhance research by promoting advanced networking between PRAABRE member institutions, to enable collaborative research on and off the island; 5. enhance biomedical research by promoting effective access to scientific literature and databases for the biomedical researchers in PRAABRE; and 6. enhance biomedical research by enabling effective management of bibliographic information by fostering the use of bibliographic software and applying it to literature searches, articles and references management and manuscript writing.
Core facility that provides the following services: Sequencing service, Genotyping service. We are a low cost, fee-for-service facility designed to provide students and researchers in Puerto Rico with access to state-of-the-art equipment for collecting sequence and genotype data. We offer full service sequencing (reaction set-up, clean up, run and delivery) and fragment analysis data generation and offer personalized support to our users.
Core facility that provides the following services: Training opportunities for protein analysis. The lab consists of materials and equipment for the identification and/or analysis of protein samples by electrospray LC/MS/MS.
Core facility that provides the following services: Genotyping analysis service, Microarray service. The lab has the following general goals: 1. To strengthen the scientific interactions between basic scientists and clinicians from the MSC and to enhance collaborations with international scientists working in molecular biology, human genetics, and infectious diseases; 2. To provide training, education, and support for the development of young scientists as well as established basic and clinical researchers with participation of internationally recognized leaders in the field; 3. To establish a centralized DNA, plasma and cell banking facility for storage of clinical samples from human blood or skin biopsies; 4. To provide basic services in molecular biology and human genetics; and 5. To initiate webcasting of training sessions in specialized areas in collaboration with the Center for Information Architecture in Research.
Core facility that provides the following services: Molecular biology services. The FGRc of the UPR is the only facility of its kind in Puerto Rico and the Caribbean. The unique infrastructure of the FGRc positions it to be the provider of expertise and services related to functional genomics research to academia, government and industry in Puerto Rico and abroad, all within one unique center.
Core facility that provides the following services: Construction and validation of random-sheared DNA fragment libraries, DNA sequencing (Sanger) service, 96-well plasmid preparation service, Genotyping/fragment analysis, BAC end sequencing, Plasmid library construction service, Genome sequencing project. The ASGPB genome infrastructure currently consists of several state-of-the-art capillary-based DNA sequencers and accessory equipment to deal with large sample volumes. The facility can process up to 9000 samples per day with a projected sequence output of 6.75 Million bases. Several prokaryotic and one eukaryotic genome project are currently in progress. The facility offers DNA sequencing services for a wide range of templates including plasmid DNA, PCR fragments, cosmid DNA, and Bacterial Artificial Chromosomes (BACs). Sequencing reactions are performed using Applied Biosystems BigDye terminator chemistry and are run on ABI 3730XL capillary-based DNA sequencers.
Core facility that provides the following services: Cell cycle analysis with live or dead cells, Cell cycle analysis service, Fluorescent cell (particle) analysis, Fluorescent cell (particle) sorting service. The Flow Cytometry Facility, operated out of the School for Ocean, Earth Sciences and Technology at the University of Hawaii, provides state of the art instrumentation for analyzing and sorting particles. Flow cytometers detect particles based on their size (scatter) and fluorescence (auto or imparted by a dye). These particles can be enumerated or simply characterized as to their scatter and fluorescence characteristics. Multiple populations can be separated visually and if desired, physically, based on these properties.
ESF project support comes under four categories: # New Funded Grants: The ESF supports researchers in planning proposals that will utilize ESF capabilities. For funded grants, the support should ideally begin at the early proposal stage. In consultation with the researcher, ESF can suggest practical and creative ways of obtaining and recording the desired data. # Support for Ongoing Funded Programs: The Engineering Support Facility has personnel and experience to repair and maintain laboratory instruments and equipment. In some cases, the existing laboratory instruments need some custom enhancements or adaptations for the particular science in view. ESF has experience going back over 35 years in custom modifications and enhancements to existing instruments. # Machine Shop: The ESF has a well-equipped machine shop and an expert instrument maker. # Pressure Test Facilities: The ESF operates a hydraulic pressure test vessel that can test pressure cases from 15 to 10,000 psia, with electronic feed-thru capability. The test vessel can accommodate objects up to 30 inches in outside diameter by 13 feet length.
Core facility that provides the following services: Necropsy and tissue collection, Blood chemistries service, Bronchoalveolar lavage service, Cerebro-spinal tap service. The Animal Resources Center (ARC) is a part of the Unit of Comparative Medicine at the Medical Sciences Campus (MSC) of the University of Puerto Rico (UPR), committed to offer quality services to the university community and private entities, which through an accredited and properly regulated facility, and highly qualified personnel, provides care and maintenance of animals to be used in research.
Our core provides a standardized library of pathogens and reagent materials.
Core facility that provides the following services: Training and advice for general imaging techniques, Histology processing service, Hematoxylin and eosin staining service, Training and advice for general histology techniques. This lab provides routine histology processing, specialized histochemical and immunohistological techniques, and access to several microscopic platforms. The core also provides technical assistance, training, and consultation in histological and imaging techniques to investigators throughout the University on a cost-recovery basis.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 17,2026. Core facility provides the following services: DNA sequencing service, DNA fragment sizing and genotyping service, Real-time PCR analysis, DNA microarray analysis service, Protein sequencing service. The Greenwood Molecular Biology Facility is a primary research infrastructure operated by the Biotechnology Program of the Pacific Biosciences Research Center. Core serves the biomedical and molecular biology research and educational programs of the University and its associated institutions.
The Biostatistics and Data Management Facility (BDMF) was established with a primary mission to provide a range of customized statistical and database management services for RCMI researchers. Realizing a need for a consolidated and integrated statistical resources for biomedical researchers and clinicians at the John A. Burns School of Medicine, the BDMF has rapidly extended services to other programs and groups, including the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases (APITMID), Pacific Biosciences Research Center (PBRC), Excellence in Partnerships for Community Outreach, Research on Health Disparities, and Training (EXPORT), Specialized Neuroscience Research Program (SNRP-I/II), Center of Biomedical Research Excellence (COBRE), Centers of Clinical Research Excellence (CCRE), Clinical Research Education and Career Development (CRECD), RCMI clinical Research Infrastructure Initiative (RCRII), and IDeA Networks of Biomedical Research Excellence (INBRE). The overall mission of the BDMF is to provide quantitative resources essential for investigators to conduct methodologically rigorous medical research in a timely, cost-effective manner. (http://www5.pbrc.hawaii.edu/bdmf/index.html)
Core facility that provides the following services: Tissue embedding service, Tissue sectioning service, Immunohistochemistry service, In situ hybridization service, DNA extraction service, Tissue microarray slides service, Tissue microarrays service, Genotyping service. The Pathology Shared resource capitalizes on the existing infrastructure of the Center''s tissue repository. The Repository currently consists of fixed, paraffin-embedded tissue specimens from hospitals and laboratories statewide. The purpose of the repository is to provide tissue specimens to Center members and other investigators for research purposes. A priority is placed on the provision of specimens for population-based research and peer-reviewed, extramurally funded projects. The repository is a part of the Residual Tissue Repository Program of the NCI SEER program (http://seer.cancer.gov/biospecimen/).
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 17,2026. The Computer Network Support Facility delivers services, information and tools to enhance the scientific productivity of biomedical and bioscience investigators at the University of Hawaii at Manoa; Hawaii; USA. Our clients include researchers, administrators and staff in the Pacific Biosciences Research Center and those associated with NIH center grants in the John A. Burns School of Medicine and other departments. Because the majority of our funding comes from the University of Hawaii Research Centers in Minority Institutions Program, we emphasize the development of computer and network tools that are useful to RCMI investigators.(http://www5.pbrc.hawaii.edu/cnsf/index.html)
Ontology of the international standard diagnostic classification for all general epidemiological, many health management purposes and clinical use.
Nutrition Support Staff at CRCH provides dietary assessment information that will support diet-related cancer research studies. The staff of the resource perform several services: * Maintain a food composition table with information on up to 174 nutrients and food components for over 2300 foods. * Maintain a supplement composition table for up to 217 nutrients and food components in over 3300 dietary supplements. * Develop quantitative scannable food frequency questionnaires for use in epidemiologic studies and provide the nutrient composition data needed for the analysis of questionnaire responses. * Review the accuracy of food records, dietary recalls, and dietary supplement questionnaires, and assist with data entry procedures. * Provide training for project staff in appropriate dietary data collection methods. * Assist with the design, analysis, and interpretation of dietary data for studies of diet and cancer.