Curator Dashboard

The YUI Library is a set of utilities and controls, written with JavaScript and CSS, for building richly interactive web applications using techniques such as DOM scripting, DHTML and AJAX. YUI is available under a BSD license and is free for all uses. YUI is proven, scalable, fast, and robust. Built by frontend engineers at Yahoo! and contributors from around the world, it''s an industrial-strength JavaScript library for professionals who love JavaScript.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Provides equipment for TEER measurement, nitric oxide testing, and electro-physiology applications.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

An organization that promotes the highest possible standards of medical ethics. The WMA provides ethical guidance to physicians through its Declarations, Resolutions and Statements. These also help to guide National Medical Associations, governments and international organizations throughout the world. The Declarations, Resolutions and Statements cover a wide range of subjects, including an International Code of Medical Ethics, the rights of patients, research on human subjects, care of the sick and wounded in times of armed conflict, torture of prisoners, the use and abuse of drugs, family planning and pollution.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

A substantial biological challenge is to understand the regulation and execution of developmental decisions that lead from multipotential, undifferentiated precursor cells to their specialized differential products. In the World lab at the California Institute of Technology, we are interested in several interrelated aspects of this problem, and we also work to develop new methods for studying it. The particular cell lineage problem we study begins with the specification of mesoderm in early development and continues to the final differentiation of skeletal muscle or cardiac muscle in the fully developed animal. To study this process we use the mouse as our experimental system. Molecular-level analyses use cell culture model systems and transgenic mice. These projects include studies of in vitro and in vivo protein-DNA interactions and of factors that amplify or suppress expression activity. Computational approaches involve the development of algorithms for use in large-scale gene expression analysis and the construction of a simulator framework for regulation in muscle development.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on Jan 16th 2025. WinLTP is a stimulation, data acquisition and on-line analysis electrophysiological software for studying Long-Term Potentiation (LTP), Long-term Depression (LTD), and related phenomena. WinLTP is multitasking and simultaneously runs 1) LTP stimulus/acquisition/analyzing sweeps with protocol scripting, and 2) continuous acquisition saving Axon Binary Files (abf). WinLTP runs on Windows PCI bus computers and uses National Instruments PCI M-Series boards and Axon Instruments'' Digidata 1320A and 1322A data acquisition boards. Other software that can use the M-Series boards includes Axograph Scientific''s AxoGraph X, WaveMetrics'' IGOR, National Instruments'' LabView, John Dempster''s Strathclyde Electrophysiology Suite (WinWCP and WinEDR), Silver lab''s Nclamp, and QUB data acquisition., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Bioinformatics, statistical genetics, functional genomics, databases and scientific computing support and services for The Wellcome Trust Centre for Human Genetics to support the disease gene cloning projects within the centre and to maintain independent research in development of methods, algorithms and software for mapping multifactorial trait loci. The group has current research foci in the areas of sequence alignment statistics, comparative genomics, ancestral haplotype construction, LIMS database development, QTL linkage and association methods, variability in patterns of linkage disequilibrium and multivariate modelling of quantitative traits.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Provides support for the Apache community of open-source software projects. The Apache projects are characterized by a collaborative, consensus based development process, open and pragmatic software license, and a desire to create high quality software that leads the way in its field.

• Resource
• SciCrunch
• 14 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. Following completion of the acquisition of Rosetta Biosoftware assets from Merck & Co., Inc. by Microsoft Corp. on June 26, 2009, Merck & Co., Inc. selected Ceiba Solutions, Inc (http://www.ceibasolutions.com) as the provider of product support for Rosetta Resolver, Elucidator and Syllego customers. Ceiba Solutions is a software and IT services company helping customers streamline and extend business processes through composite software development, application integration, and managed application services. Ceiba currently serves Life Science industry customers with outsourced managed services for R&D applications, as well as business software and integrated business processes. Ceiba Solutions is an active member of the Massachusetts Biotechnology Council and the BayBio Council. Ceiba Solutions has assumed complete responsibility for software maintenance and support associated with Rosetta Biosoftware product Licensees who are eligible for continued Technical Support and Software Upgrade Protection, and will retain that responsibility throughout the remainder of the 24 month Desupport Period.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

INB is a technological plattform of Genoma Espaa. A National Network for coordination, integration and development of Spanish Bioinformatics Resources in genomics and proteomics projects. The INB (Instituto Nacional de Bioinformtica) is a community-driven technology platform of Genoma Espana founded in 2003 with the mission to consolidate Bioinformatics as a scientific discipline and to generate and apply solutions for the development and execution of projects related to genomics and proteomics, providing technical support in Bioinformatics to laboratories, institutions and companies throughout the Spanish territory.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

This collection of Free Statistics Calculators offers a wide range of descriptive and explorative types of statistical measures and analysis: Central Tendency, Average, Mean, Median, Variability, Interquartile Range, Concentration, Lorenz Curve, Gini Coefficient, Skewness, Kurtosis, Quartiles, Percentiles, Notched Boxplot, Histogram, Correlation, Partial Correlation, Rank Correlation (Spearman and Kendall), Simple Regression, Kernel Density Estimation, Harrell-Davis Quantiles, Bivariate KDE, Correlation Matrix, Stem-and-leaf plot, Explorative Data Analysis

• Resource
• SciCrunch
• 17 years ago - by Anonymous

A method to assess the outcome of nonsynonymous SNVs using a consensus deleteriousness score that combines various tools (e.g. SIFT, Polyphen2, MutationAssessor).

• Resource
• SciCrunch
• 13 years ago - by Anonymous

WDIN is a collaborative project working to develop a Web-based monitoring and reporting system to provide state and federal resource managers, animal disease specialists, veterinary diagnostic laboratories, physicians, public health workers, educators, and the general public with access to data on wildlife diseases, mortality events, and other critical related information. Data are contributed voluntarily, with partners deciding which data they choose to share.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Our principal research interest is the organization and the dynamics of the large-scale neuronal networks of the brain that characterize mental functions, and the understanding of disturbances of these networks in patients with brain dysfunctions. Electromagnetic imaging based on high-resolution EEG is our principal instrument to study these questions. It is combined with Transcranial Magnetic Stimulation (TMS), Functional Magnetic Resonance Imaging (fMRI), and multichannel intracranial recordings in patients. Sponsors: Swiss National Science Foundation Fondation Louis Jeantet de Mdecine Fondation Leenards

• Resource
• SciCrunch
• 17 years ago - by Anonymous

The DeRisi Lab focuses on genomic approaches to the study of infectious disease. Specifically, we are studying Plasmodium falciparum, the causative agent of the most deadly form of human malaria. We are also involved in a major effort for the discovery of new viral pathogens associated with diseases of unknown etiology. Software tools developed in the lab include: HMMSplicer discovers splice sites in high throughput sequencing datasets without using gene models. HMMSplicer can also be used to find non-canonical junctions as well. HMMSplicer was benchmarked on publickly available A. thaliana, H. sapiens, and P. falciparum datasets and performs well on all genomes. Information about the datasets tested, including the exact command parameters and the final results, is provided. HMMSplicer is implemented in Python and is freely available for all. VersaCount is a simple application to assist with the counting of cells by microscopy. When used with a numeric keypad, it can significantly increase counting efficiency when compared with a traditional clicker. Although it was designed for malaria work, it can be customized for a wide variety of cell counting applications. VersaCount was written by Charlie Kim. ExpressionNet is a program written by Jingchun Zhu that uses Bayesian network learning algorithms to explore relationships among random variables to generate network models. The software has been used to study the transcriptional response to environmental perturbations in budding yeast. Details of the program and the study of yeast transcription using Bayesian Networks was published in PLoS ONE. DNA microarrays may be used to identify microbial species present in environmental and clinical samples. However, automated tools for reliable species identification based on observed microarray hybridization patterns are lacking. We present an algorithm, E-Predict, for microarray-based species identification. ArrayOligoSelector (AOS) is an open source program developed by Jingchun Zhu for the purpose of systematically designing gene-specific long oligonucleotide probes for entire genomes. For each open reading frame, the program optimizes oligo selection based upon several parameters, including uniqueness, complexity, secondary structure, GC content, and 3'' end proximity. AOS also is hosted at SourceForge. This site contains documentation and a user-friendly how-to. ArrayMaker 2 provides high performance robotic control of microarrayer robots with an incredibly intuitive, easy to use interface. ArrayMaker 2 is optimized for use with the new generation of ultra fast linear servo driven arrayers, yet it is backwards compatible with the original MGuide style of ball-screw driven arrayers.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Retroelements constitute important evolutionary forces for the genome of higher organisms, yet their uncontrolled spread, whether from endogenous loci or within the context of viral infections, can cause diseases such as cancer, hepatitis and AIDS. Correspondingly, a variety of host-encoded activities limit this process, belonging to a line of defense commonly called intrinsic or innate immunity, which notably contributes to taming endogenous retroelements and to restricting the cross-species transmission of retroviruses. Our work aims at characterizing the relationship between retroelements and their hosts, which has recently led us to become more generally interested in epigenetic mechanisms regulating the expression of mammalian genomes.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

A large collection of tools for basic and advanced analyses of nucleotide and protein sequences. The tools are wrapped into a common user interface making handling, storage, retrieval and viewing the results easy and logical. A seqtools project can accommodate many thousand sequences making unattended batch analyses like database searching at NCBI painless with the robust search engine included in seqtools.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

SABiosciences, as part of QIAGEN, offers nucleic acid (DNA, RNA, miRNA) and protein isolation, preparation and purification services, as well as assay,array, sequencing, NGS and biomarker services and lab essentials.Offers PCR services, assays, array systems, and expression vectors. Acquired by QIAGEN in 2009.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

The SABC is the collaborative university Centre for R&D in agricultural and veterinary biotechnology in Western Australia. It provides platform technologies and world class equipment and facilities for R&D in agricultural biotechnology to researchers from universities, state government and industry. More than 20 research groups and companies rent space and use the SABC facilities. It is based at Murdoch University in Perth. Our Vision To be an eminent, internationally recognized centre for research and development in agriculture and veterinary biotechnology Our Mission To provide state-of-the-art facilities and equipment enabling multi disciplinary research in biotechnology which under pins the agricultural and veterinary industry, for the benefit of the community. This will be achieved by being recognised as the centre for agricultural biotechnology in WA providing national and international research links and collaborations fostering establishment of national centres in leading edge technologies Characteristics of the SABC * The SABC is a multi-user centre with a research spend of about $9 million pa * There is a critical mass of more than 225 researchers * The SABC combines university, state government and industry researchers in one cost-effective centre * The SABC operates as a ''Research Hotel'' in which different groups rent common laboratory space and access to platform technologies * The SABC supports incubation and co-location of new ag biotech companies in WA * The SABC promotes collaborative research, undertakes contract research, and provides many local, national and international linkages * SABC researchers are members of eight agricultural Cooperative Centres (CRCs) Research Focus The research focus is on molecular activities that involve or promote primary production of commercial livestock, crop plants or microbes, or their subsequent processing for added value. The SABC also supports research in biomedical sciences, and environmental biotechnology. Deliverables and Outcomes SABC researchers have an outstanding track record of outputs and outcomes. These include the provision of co-located, state-of-the art, well run platform technologies for all WA researchers plant breeding support leading to improved crop varieties (molecular markers, yield, resistance to diseases and pests, better quality, variety ID, diagnostics), improved productivity and health of livestock, and biomedical diagnostics. Facilities and platform technologies The SABC provides the most comprehensive set of equipment and facilities for biotechnology R&D in WA, with full facilities for: cell and molecular biology, robotics, high throughput agricultural genetic analyses and diagnostics, structural, comparative and functional genomics, microarray technologies, proteomics and mass spectroscopy and bioinformatics support via the (CBBC). Training and Mentoring The SABC plays a major role in advanced training in ag biotech. There are about 100 Honours and PhD students in the research complement. The SABC also runs a series of hands on short courses in molecular biology, gene mapping, diagnostics, proteomics and bioinformatics. In 2005 new postgraduate certificate and diploma courses on Application of Molecular Technologies was established at Murdoch University, run by internationally qualified SABC researchers. These provide advanced education at the Postgraduate Certificate, Diploma and MSc levels, for local and international participants. click here for details The SABC runs the following hands-on training workshops: * Introduction to Molecular Biology * Molecular Mapping Techniques in Diagnostic Biotechnology * High Throughput Genetic Analysis * Introduction to Proteomics * Advanced Proteomics * Bioinformatics (with the CBBC) Competitive Advantages The SABC: * combines crop, veterinary and biomedical research in biotechnology in one centre * is multidisciplinary and inclusive * provides enabling facilities, platform technologies and common laboratories * is highly cost effective Researcher Groups Using the SABC * Division of Health Sciences (Murdoch)/Veterinary Sciences * Division of Science and Engineering (Murdoch)/Biological Sciences and Biotechnology * UWA (Natural Resources and Agriculture, Biochemistry) * Curtin University (Molecular Biotechnology, Horticulture) * Edith Cowan University (Human Genetics) * WA Dept of Agriculture (animal, plant, microbial) * Fisheries * Perth Zoo * Plant Biotechnology Research Group * Australian Centre for Necrotrophic Fungal Pathogens (ACNFP) * Rumen Biotechnology * Centre for High Throughput Agricultural Genetic Analysis (CHAGA) * Veterinary Virology, Parasitology, Microbiology * Saturn Biotech Pty Ltd * Grain Biotech Australia Pty Ltd * Proteomics International * Lighthouse Laboratories Pty Ltd * ID PLUS Pty Ltd * Royal Perth Hospital * Fremantle Hospital * Australian Neuromuscular Research Institute (ANRI) Partnering Opportunities The SABC can provide full facilities for contract R&D, start up companies or co-location of existing companies in agricultural, veterinary and biomedical sciences via its incubation program. Contact the Director for further information. Partnering Needs Investors interested in commercializing outputs of SABC researchers.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Software products and services for behavioral and physiological research, including control software for experiments on primates and rodents, analysis of electrophysiological data, display of visual and auditory stimuli, and synchronization of experimental data from other measurement devices. The company offers a range of consulting services and provides product support services that assist customers in developing, deploying, and managing custom behavioral testing programs.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Rules-Based Medicine (RBM) uses proprietary Multi-Analyte Profiling (MAP) technology to make life science research and drug and diagnostic development programs more efficient and effective. Whether measuring hundreds of biomarkers or simply a few, our approach provides reproducible, quantitative immunoassay data from a small sample volume at a cost-effective price. RBM is CLIA certified and supports GLP studies. * Quality: All immunoassays are validated to clinical laboratory standards. This means complete validation for the clinic, not fit for purpose validation which at RBM means inferior validation. Learn More * Content: We have the most comprehensive menu of biomarker immunoassays available. * Small Sample Volumes: Multiplexing provides you with more data using a smaller sample volume. * Cost Effective: Multiplexing and automation combine to deliver high quality data at reasonable prices. * Ease of use: Ship us your samples and get results within 2 weeks. Rules-Based Medicine (RBM), the worlds leading multiplexed biomarker testing laboratory, provides comprehensive protein biomarker products and services based on its Multi-Analyte Profiling (MAP) technology platform. RBMs biomarker testing service provides pre-clinical and clinical researchers with reproducible, quantitative, multiplexed immunoassay data for hundreds of proteins in a cost-effective manner, from a small sample volume and from multiple species. Our biomarker testing laboratory is CLIA certified and supports GLP studies. Most diseases and drug effects manifest themselves in abnormal levels of specific biomarkers found in the peripheral blood. By providing multiplexed, quantitative, and reproducible tests for hundreds of biomarkers, RBM enables research that historically was not available due to sample volume requirements and associated costs. Use of our testing services can identify the sources of both the positive and negative effects of drugs during pre-clinical research and clinical trials. Biomarker testing results identify patients most likely to respond to a given therapy and the biochemical reason for that response, making clinical trials more successful and effective. Through its wholly owned subsidiary EDI GmbH, RBM provides Human Organo-Typic (HOT) cell culture systems. These co-culture systems consist of multiple primary cell types grown in a 3-D architecture that closely mimic particular human organs and are an ideal platform for ex vivo studies of drug safety and efficacy. RBM combines EDIs cell culture systems with its HumanMAP biomarker testing services to provide researchers with an unprecedented view of the physiological and biochemical impact of a new drug compound or consumer product prior to testing in a human subject. RBM also performs custom assay development, participates in co-sponsored research programs, and pursues in-licensing of novel high-value assays.

• Resource
• SciCrunch
• 17 years ago - by Anonymous